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FINAL PROGR AM - American Society of Gene & Cell Therapy

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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 89<br />

ABSTRACTS<br />

FRIDAY, JUNE 3<br />

717<br />

Cancer <strong>Gene</strong> Therapeutic Approaches Using an AAV-<br />

Mediated <strong>Gene</strong> Delivery System Containing Antisense<br />

VEGF-A cDNA<br />

Keerang Park, Mee-Young Ahn, Seock-Yeon Hwang, Young-<br />

Hwa Cho, Bong-Su Kang, Youn-Ju Kim, Sung-Ha Cho,<br />

Young-Min Kim, So-Yong Yi, Sun-Kyung Kim Eun-Jung<br />

Park, Kang-Eun Lee<br />

718<br />

Development <strong>of</strong> AAV and Adenovirus Cocktail Vector<br />

System for Efficient Cancer <strong>Gene</strong> <strong>Therapy</strong> by Human<br />

TERTC27 Polypeptide<br />

Yi Gao, Samuel S. Ng, Chen Yang, David Chau, JunJian<br />

Huang, Cui-fen Huang, Hsiang-fu Kung, Marie C. Lin<br />

719<br />

Neutralization <strong>of</strong> Free but Not <strong>Cell</strong> Associated Oncolytic<br />

Measles Vurses by Antibody and Complement<br />

Ianko Iankov, Stephen J. Russell<br />

720<br />

EGFRvIII Retargeted Oncolytic Measles Virus Strains<br />

Have Significant Antitumor Activity Against Gliomas<br />

Cory Allen, Sompong Vongpunsawad, Takafumi Nakamura, C.<br />

David James, Mark Schroeder, Roberto Cattaneo, Stephen J.<br />

Russell, Evanthia Galanis<br />

721<br />

Measles Virus for Cancer <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Primary Liver<br />

Tumors<br />

Boris R. A. Blechacz, Patrick Splinter, Greiner Suzanne, Mark<br />

J. Federspiel, Kah-Whye Peng, Nicholas F. LaRusso, Stephen J.<br />

Russell<br />

722<br />

Antitumor Effect <strong>of</strong> IL-24 Mediated by Tumor Targeting<br />

Vector ZD55 Is Much Better Than That Mediated by<br />

Replication Deficient Adenovirus<br />

Li-li Zhao, Jin-fa Gu, Ai-wen Dong, Yan-hong Zhang, Lingfeng<br />

He, Jin-he Zhang, Yi-gang Wang, Zi-lai Zhang, Qi-jun<br />

Qian, Cheng Qian Xin-yuan Liu<br />

723<br />

VSV-G Pseudotyped, Semi-Replication Competent MLV<br />

Retroviruses for Cancer <strong>Gene</strong> <strong>Therapy</strong><br />

Jian Qiao, Jesus Moreno, Timothy Kottke, Michael Forshaw,<br />

Rosa Maria Diaz, Richard Vile<br />

724<br />

Herpes Simplex Virus 1 Amplicon Vector-Mediated<br />

siRNA Targeting Epidermal Growth Factor Receptor<br />

Inhibits Growth <strong>of</strong> Human Glioma <strong>Cell</strong>s in Culture and<br />

In Vivo<br />

Okay Saydam, Daniel Glauser, Irma Heid, Gulen Turkeri,<br />

Andreas Jacobs, Mathias Ackermann, Cornel Fraefel<br />

725<br />

Seneca Valley Virus, a Novel Systemically Deliverable<br />

Oncolytic Virus for the Treatment <strong>of</strong> Small <strong>Cell</strong> Lung<br />

Cancer and Other Neuroendocrine Cancers<br />

Paul L. Hallenbeck, Seshidhar P. Reddy, Shanthi Ganesh<br />

726<br />

Effect <strong>of</strong> G-CSF-Mediated Mobilization on Tumor<br />

Homing <strong>of</strong> <strong>Gene</strong>tically Modified, Bone Marrow Derived<br />

<strong>Cell</strong>s<br />

Zong-Yi Li, Shaoheng Ni, Hans-Peter Kiem, Andre Lieber<br />

727<br />

<strong>Gene</strong>-Modified Mesenchymal Stem <strong>Cell</strong>s Selectively<br />

Engraft in Stroma <strong>of</strong> Ovarian Carcinomas and Control<br />

Tumor Growth<br />

Jennifer Dembinski, Matus Studeny, Claudia Zompetta,<br />

Michael Andreeff, Frank Marini<br />

728<br />

Anti-TAG-72 Immunoliposomes for Efficient Tumor-<br />

Targeted <strong>Gene</strong> <strong>Therapy</strong><br />

Keun-Sik Kim, Hong Sung Kim, Eun Jung Kim, Jong Chul<br />

Kim, In-Ho Song, Hyo Jeong Hong, Yong Serk Park<br />

729<br />

C-Met Antisense Plasmid Liposome Complex Increases<br />

Radiation Sensitivity <strong>of</strong> Lung Tumor <strong>Cell</strong>s In Vivo or In<br />

Vitro<br />

Yunyun Niu, Laura Stabile, Michael W. Epperly, Jill Siegfried,<br />

Joel S. Greenberger<br />

730<br />

Cancer Specific Promoters for <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Small<br />

<strong>Cell</strong> Lung Cancer<br />

Nina Pedersen, Mikkel W. Pedersen, Michael S. Lan, Thomas<br />

T. Poulsen, Hans S. Poulsen<br />

731<br />

Completely Elimination <strong>of</strong> Xenograft SW620 Cancer by<br />

Combined Tumor Targeting MnSOD and Trail <strong>Gene</strong>s<br />

Yan-hong Zhang, Jin-fa Gu, Li-li Zhao, Yi-gang Wang, Jinhui<br />

Wang, Ling-feng He, Wei-guo Zou, Qi-Jun Qian, Cheng<br />

Qian, Xin-yuan Liu<br />

732<br />

Defining Tropism <strong>of</strong> Oncolytic Vectors by Protease<br />

Availability: Measles Viruses Selectively Fusing Matrix-<br />

Metalloproteinase Expressing <strong>Cell</strong>s<br />

Christoph Springfeld, Veronika von Messling, Christian<br />

Buchholz, Roberto Cattaneo<br />

<strong>Gene</strong> Regulation: Overcoming Obstacles to <strong>Gene</strong><br />

Transfer and Expression<br />

733<br />

The Human XIST <strong>Gene</strong> Promoter Prevents Silencing <strong>of</strong><br />

an Integrated Reporter <strong>Gene</strong><br />

Michael R. Greene, Christopher H. Lowrey

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