FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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86<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
FRIDAY, JUNE 3<br />
668<br />
Non-Viral <strong>Gene</strong> Delivery for Ocular Diseases with<br />
Compacted DNA Nanoparticles<br />
Rafal Farjo, Jeff Skaggs, Alexander B. Quiambao, Mark J.<br />
Cooper, Muna I. Naash<br />
669<br />
Sonic Hedgehog (SHH) Is Required for Retinal Angiogenesis<br />
and Its Inhibition Prevents Retinal<br />
Neovascularization<br />
Enrico M. Surace, Alessandra Tessitore, Gabriella Cotugno,<br />
Aniello Vitale, Alberto Auricchio<br />
670<br />
Mutation Independent Silencing <strong>of</strong> <strong>Gene</strong>s Involved in<br />
Retinal Degeneration by RNA Interference (RNAi) and<br />
Trans Complementation by a Codon Exchanged RNAi-<br />
Resistant Transgene<br />
Siobhan Cashman, Erin Binkley, Rajendra Kumar-Singh<br />
671<br />
Nerve Growth Factor and Neurotrophin-3 Delivered by<br />
HSV <strong>Gene</strong> Transfer Reverses Diabetic Neuropathy<br />
James R. Goss, Munmun Chattopadhyay, William F. Goins,<br />
Darren Wolfe, Marina Mata, Joseph C. Glorioso, David J. Fink<br />
<strong>Gene</strong> <strong>Therapy</strong> for Connective Tissue<br />
672<br />
The Effect <strong>of</strong> Serine Protease Inhibitor 6 (SPI-6) <strong>Gene</strong><br />
Transfer on a Mouse Model <strong>of</strong> Sjögren’s Syndrome<br />
Fumi Mineshiba, Beatrijs M. Lodde, Jianghua Wang, Livia A.<br />
Casciola-Rosen, Antony Rosen, Bruce J. Baum<br />
673<br />
Plasmid-Based GHRH Supplementation Delivered by<br />
Electroporation as a Treatment <strong>of</strong> Arthritis/Laminitis in<br />
Horses<br />
Patricia A. Brown, David M. Hood, Ruxandra Draghia-Akli<br />
674<br />
Molecular, Biochemical and Biomechanical Analysis <strong>of</strong><br />
Articular Cartilage Repaired with <strong>Gene</strong>tically Modified<br />
Chondrocytes Expressing Insulin-Like Growth Factor-I<br />
Laurie R. Goodrich, Eric Strauss, Chris T. Chen, Chisa<br />
Hidaka, Paul D. Robbins, Chris H. Evans, Alan J. Nixon<br />
675<br />
Enhanced Survival <strong>of</strong> Chondrocytes over Expressing<br />
Insulin like Growth Factor I in Equine Cartilage Repair<br />
Laurie R. Goodrich, Chisa Hidaka, Mary L. Strassheim, Paul<br />
D. Robbins, Chris H. Evans, Alan J. Nixon<br />
676<br />
Local Stimulation <strong>of</strong> Articular Cartilage Repair by<br />
Transplantation <strong>of</strong> Encapsulated Chondrocytes<br />
Overexpressing Human FGF-2 In Vivo<br />
Gunter Kaul, Magali Cucchiarini, David Zurakowski, Stephen<br />
B. Trippel, Dieter Kohn, Henning Madry<br />
677<br />
<strong>Gene</strong> Delivery <strong>of</strong> TNFR:Fc by Adeno-Associated Virus<br />
Vector Blocks Progression <strong>of</strong> Periodontitis<br />
Mario Taba Jr, Heather H. Huffer, Charles E. Shelburne,<br />
Jaclynn M. Kriegl, Steven A. Goldstein, Kurt H. Lustig, Haim<br />
Burstein, William V. Giannobile<br />
678<br />
Inflammatory Cytokines Regulate Transgene Expression<br />
from Rheumatoid Synoviocytes Infected with Double<br />
Stranded Adeno-Associated Virus Vectors<br />
Russell S. Traister, Sylvie Fabre, Xiao Xiao, Raphael Hirsch<br />
679<br />
Establishment <strong>of</strong> New IL-6 Receptor Inhibitor Applicable<br />
to the <strong>Gene</strong> <strong>Therapy</strong><br />
Yasuo Adachi, Naoko Yoshio, Chieko Aoki, Alexander Pereboev,<br />
David T. Curiel, Masato Yamamoto, Norihiro Nishimoto<br />
680<br />
Application <strong>of</strong> <strong>Gene</strong> <strong>Therapy</strong> to Tendon Healing:<br />
Modification <strong>of</strong> Tenocytes with Exogenous PDGF and<br />
VEGF <strong>Gene</strong>s to Promote Collagen Production<br />
Jin Bo Tang, Xiao Tian Wang, Paul Y. Liu<br />
681<br />
Hydrogel Encapsulation <strong>of</strong> Adenovirus-Transduced <strong>Cell</strong>s<br />
Expressing BMP2 for Local Osteoinduction<br />
Malavosklish Bikram, Christine Fouletier-Dilling, Andre M.<br />
Gobin, Alan R. Davis, Elizabeth A. Olmsted-Davis, Jennifer L.<br />
West<br />
682<br />
Over-Expression <strong>of</strong> Follistatin-Like Protein Exacerbates<br />
Collagen Induced Arthritis<br />
Takako Miyamae, Anthony D. Marinov, David C. Wilson,<br />
Raphael Hirsch<br />
683<br />
Adenoviral Vector-Mediated Expression <strong>of</strong> Bone Morphogenetic<br />
Protein-4 in Mesenchymal Stem <strong>Cell</strong>s<br />
Induces Differentiation into the Osteoblastic Lineage and<br />
Bone Production In Vivo<br />
Barbara Lombardo, Rosa Di Noto, Maria Teresa Esposito,<br />
Sabrina Battista, Gabriela Ciapetti, Ombretta Capitani, Luigi<br />
Nicolais, Paolo Netti, Francesco Salvatore, Lucio Pastore<br />
684<br />
Viral <strong>Gene</strong> <strong>Therapy</strong> in Tendon Healing: Adeno-Associated<br />
Virus-2 but Not Other Serotypes Effectively<br />
Transduces Intrasynovial Tenocytes with Persistent<br />
Expression <strong>of</strong> the Transgene<br />
Xiao Tian Wang, Paul Y. Liu, Jin Bo Tang