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FINAL PROGR AM - American Society of Gene & Cell Therapy

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86<br />

8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />

ABSTRACTS<br />

FRIDAY, JUNE 3<br />

668<br />

Non-Viral <strong>Gene</strong> Delivery for Ocular Diseases with<br />

Compacted DNA Nanoparticles<br />

Rafal Farjo, Jeff Skaggs, Alexander B. Quiambao, Mark J.<br />

Cooper, Muna I. Naash<br />

669<br />

Sonic Hedgehog (SHH) Is Required for Retinal Angiogenesis<br />

and Its Inhibition Prevents Retinal<br />

Neovascularization<br />

Enrico M. Surace, Alessandra Tessitore, Gabriella Cotugno,<br />

Aniello Vitale, Alberto Auricchio<br />

670<br />

Mutation Independent Silencing <strong>of</strong> <strong>Gene</strong>s Involved in<br />

Retinal Degeneration by RNA Interference (RNAi) and<br />

Trans Complementation by a Codon Exchanged RNAi-<br />

Resistant Transgene<br />

Siobhan Cashman, Erin Binkley, Rajendra Kumar-Singh<br />

671<br />

Nerve Growth Factor and Neurotrophin-3 Delivered by<br />

HSV <strong>Gene</strong> Transfer Reverses Diabetic Neuropathy<br />

James R. Goss, Munmun Chattopadhyay, William F. Goins,<br />

Darren Wolfe, Marina Mata, Joseph C. Glorioso, David J. Fink<br />

<strong>Gene</strong> <strong>Therapy</strong> for Connective Tissue<br />

672<br />

The Effect <strong>of</strong> Serine Protease Inhibitor 6 (SPI-6) <strong>Gene</strong><br />

Transfer on a Mouse Model <strong>of</strong> Sjögren’s Syndrome<br />

Fumi Mineshiba, Beatrijs M. Lodde, Jianghua Wang, Livia A.<br />

Casciola-Rosen, Antony Rosen, Bruce J. Baum<br />

673<br />

Plasmid-Based GHRH Supplementation Delivered by<br />

Electroporation as a Treatment <strong>of</strong> Arthritis/Laminitis in<br />

Horses<br />

Patricia A. Brown, David M. Hood, Ruxandra Draghia-Akli<br />

674<br />

Molecular, Biochemical and Biomechanical Analysis <strong>of</strong><br />

Articular Cartilage Repaired with <strong>Gene</strong>tically Modified<br />

Chondrocytes Expressing Insulin-Like Growth Factor-I<br />

Laurie R. Goodrich, Eric Strauss, Chris T. Chen, Chisa<br />

Hidaka, Paul D. Robbins, Chris H. Evans, Alan J. Nixon<br />

675<br />

Enhanced Survival <strong>of</strong> Chondrocytes over Expressing<br />

Insulin like Growth Factor I in Equine Cartilage Repair<br />

Laurie R. Goodrich, Chisa Hidaka, Mary L. Strassheim, Paul<br />

D. Robbins, Chris H. Evans, Alan J. Nixon<br />

676<br />

Local Stimulation <strong>of</strong> Articular Cartilage Repair by<br />

Transplantation <strong>of</strong> Encapsulated Chondrocytes<br />

Overexpressing Human FGF-2 In Vivo<br />

Gunter Kaul, Magali Cucchiarini, David Zurakowski, Stephen<br />

B. Trippel, Dieter Kohn, Henning Madry<br />

677<br />

<strong>Gene</strong> Delivery <strong>of</strong> TNFR:Fc by Adeno-Associated Virus<br />

Vector Blocks Progression <strong>of</strong> Periodontitis<br />

Mario Taba Jr, Heather H. Huffer, Charles E. Shelburne,<br />

Jaclynn M. Kriegl, Steven A. Goldstein, Kurt H. Lustig, Haim<br />

Burstein, William V. Giannobile<br />

678<br />

Inflammatory Cytokines Regulate Transgene Expression<br />

from Rheumatoid Synoviocytes Infected with Double<br />

Stranded Adeno-Associated Virus Vectors<br />

Russell S. Traister, Sylvie Fabre, Xiao Xiao, Raphael Hirsch<br />

679<br />

Establishment <strong>of</strong> New IL-6 Receptor Inhibitor Applicable<br />

to the <strong>Gene</strong> <strong>Therapy</strong><br />

Yasuo Adachi, Naoko Yoshio, Chieko Aoki, Alexander Pereboev,<br />

David T. Curiel, Masato Yamamoto, Norihiro Nishimoto<br />

680<br />

Application <strong>of</strong> <strong>Gene</strong> <strong>Therapy</strong> to Tendon Healing:<br />

Modification <strong>of</strong> Tenocytes with Exogenous PDGF and<br />

VEGF <strong>Gene</strong>s to Promote Collagen Production<br />

Jin Bo Tang, Xiao Tian Wang, Paul Y. Liu<br />

681<br />

Hydrogel Encapsulation <strong>of</strong> Adenovirus-Transduced <strong>Cell</strong>s<br />

Expressing BMP2 for Local Osteoinduction<br />

Malavosklish Bikram, Christine Fouletier-Dilling, Andre M.<br />

Gobin, Alan R. Davis, Elizabeth A. Olmsted-Davis, Jennifer L.<br />

West<br />

682<br />

Over-Expression <strong>of</strong> Follistatin-Like Protein Exacerbates<br />

Collagen Induced Arthritis<br />

Takako Miyamae, Anthony D. Marinov, David C. Wilson,<br />

Raphael Hirsch<br />

683<br />

Adenoviral Vector-Mediated Expression <strong>of</strong> Bone Morphogenetic<br />

Protein-4 in Mesenchymal Stem <strong>Cell</strong>s<br />

Induces Differentiation into the Osteoblastic Lineage and<br />

Bone Production In Vivo<br />

Barbara Lombardo, Rosa Di Noto, Maria Teresa Esposito,<br />

Sabrina Battista, Gabriela Ciapetti, Ombretta Capitani, Luigi<br />

Nicolais, Paolo Netti, Francesco Salvatore, Lucio Pastore<br />

684<br />

Viral <strong>Gene</strong> <strong>Therapy</strong> in Tendon Healing: Adeno-Associated<br />

Virus-2 but Not Other Serotypes Effectively<br />

Transduces Intrasynovial Tenocytes with Persistent<br />

Expression <strong>of</strong> the Transgene<br />

Xiao Tian Wang, Paul Y. Liu, Jin Bo Tang

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