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FINAL PROGR AM - American Society of Gene & Cell Therapy

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78<br />

8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />

ABSTRACTS<br />

FRIDAY, JUNE 3<br />

531<br />

Balloon Catheter-Mediated Hepatic Vein Delivery <strong>of</strong> a<br />

Viral Vector Mitigates Neutralization by Anti-Viral<br />

Antibodies and Results in Efficient Transduction <strong>of</strong><br />

Rabbit Liver<br />

Bradley L. Hodges, Kristin M. Taylor, Qiuming Chu,<br />

Samantha E. Scull, Rebecca G. Serriello, Scott C. Anderson,<br />

Ronald K. Scheule<br />

532<br />

Effects <strong>of</strong> a New YB-1 Dependent Adenovirus (XVir) in<br />

Human Prostate Cancer <strong>Cell</strong> Lines and in a Xenograft<br />

Mouse Model<br />

Klaus Mantwill, Nadia Koehler-Vargas, Alexandra<br />

Bernshausen, Uwe Treiber, Rudolf Hartung, Bernd Gansbacher,<br />

Per Sonne Holm<br />

533<br />

Enhanced Transduction <strong>of</strong> Dendritic <strong>Cell</strong>s by FCgRI-<br />

Targeted Adenovirus Vectorsgð<br />

Ramil E. Sapinoro, Angela P. H. Burgess, Stephen Dewhurst<br />

534<br />

Optimising Expression Cassettes for Vascular <strong>Gene</strong><br />

Expression<br />

Stephen J. White, Melanie A. Roberts, Jeremy R. Sanford, Javier<br />

F. Cáceres, Andrew C. Newby<br />

535<br />

Long-Term Correction <strong>of</strong> Hyperbilirubinemia in a Rat<br />

Model <strong>of</strong> Crigler-Najjar Syndrome Type 1<br />

Viraj P. Mane, Gabriele Toietta, Wilma Norona, Milton<br />

Finegold, Phil Ng, Arthur L. Beaudet, Anthony F. McDonagh,<br />

Brendan Lee<br />

536<br />

Adenoviral Vector-Mediated <strong>Gene</strong> <strong>Therapy</strong> for<br />

Adenocortical Carcinoma: Therapeutic Strategies and<br />

Safety Considerations<br />

Luisa Barzon, Urska Trost, Monia Pacenti, Anna-Lisa Stefani,<br />

Marta Trevisan, Giulia Masi, Karina Fincati, Giorgio Palù<br />

537<br />

Transcriptionally Targeting the Survivin Promoter to<br />

Human Gliomas<br />

Zeng B. Zhu, Winan J. Houdt, Yosef S. Haviv, Baogen Lu,<br />

Minghui Wang, Angel A. Rivera, Ilya V. Ulasov, Maciej S.<br />

Lesniak, <strong>Gene</strong> P. Siegal, Clemens M. F. Dirven David T.<br />

Curiel<br />

538<br />

Fiber Chimeric Oncolytic Adenoviral Vectors Mediate<br />

Efficient <strong>Gene</strong> Transfer and Oncolysis <strong>of</strong> Head and Neck<br />

Cancer and Melanoma <strong>Cell</strong>s In Vitro and In Vivo<br />

Shanthi Ganesh, Yuanhao Li, Peter Working, P. Seshidhar<br />

Reddy, De-Chao Yu<br />

539<br />

Antitumor Activity <strong>of</strong> an hTERT-Specific, GFP Expressing<br />

Oncolytic Adenovirus<br />

John J. Davis, Li Wang, Lidong Zhang, Wei Guo, Fuminori<br />

Teraishi, Kai Xu, Lin Ji, Bingliang Fang<br />

540<br />

Re-Targeting <strong>of</strong> Adenoviral Vector-Mediated Interferongð<br />

<strong>Gene</strong> Transfer to Colon Cancer <strong>Cell</strong>s That Express the<br />

Human Carcinoembryonic Antigen<br />

Maaike Everts, Jing Li, Krishnakant Pondugula, Angel A.<br />

Rivera, David T. Curiel, J. Michael Mathis<br />

541<br />

Oncolytic Effects <strong>of</strong> Conditionally Replicating<br />

Adenoviruses (CRAds) with Mutations in E1A and E1B<br />

Regions<br />

Hyunhee Kim, Jaesung Kim, Kyung-Ju Choi, Pyung Hwan<br />

Kim, Tae Young Koo, Ahmed M. Al-Abd, Hye Jin Choi, Joo-<br />

Hang Kim, Chae-Ok Yun<br />

542<br />

Targeting EGFR with Metabolically Biotinylated Fiber-<br />

Mosaic Adenovirus<br />

Larisa Pereboeva, Svetlana Komarova, Selvarangan<br />

Ponnazhagan, David T. Curiel<br />

543<br />

Enhanced Glia-Specific Expression Using GFAP-<br />

’Super’Promoters in an Adenoviral Context In Vitro and<br />

In Vivo<br />

Bertie de Leeuw, Maarten ter Horst, Mark Rodijk, Rob C.<br />

Hoeben, Michael Brenner, Peter A. E. Sillevis Smitt<br />

544<br />

Interferon alpha-2b <strong>Gene</strong> Delivery for Bladder Cancer<br />

Demonstrates Feasibility <strong>of</strong> Repeated Intravesical Dosing<br />

with an Adenovirus Vector<br />

Heidrun Engler, Robert J. Connor, Jennifer M. Anderson, Drake<br />

LaFace, Daniel C. Maneval<br />

545<br />

Adenovirus Mediated <strong>Gene</strong> Transfer and Oncolysis In<br />

Vitro in Head and Neck Cancer and Melanoma <strong>Cell</strong>s<br />

Enhanced by Polycations<br />

Lian Mo, Gary Lee, Shanthi Ganesh, Yuanhao Li, Peter<br />

Working, P. Seshidhar Reddy, De-Chao Yu<br />

546<br />

<strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Ovarian Cancer by IAI.3B Promoter<br />

Driven Oncolytic Adenovirus<br />

Katsuyuki Hamada, Toshiro Shirakawa, Akinobu Gotoh<br />

547<br />

Improvement <strong>of</strong> Liver <strong>Gene</strong> Transfer by First and Third<br />

<strong>Gene</strong>ration Adenoviral Vectors<br />

Julien S. Crettaz, Pedro Berraondo, Itsaso Mauleon, Laura<br />

Ochoa, Veijay Shankar, Miguel Barajas, Maider Zabala, Nico<br />

van Rooijen, Stefan Kochanek, Cheng Qian Jesus Prieto, Ruben<br />

Hernandez-Alcoceba, Gloria Gonzalez-Aseguinolaza

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