FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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78<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
FRIDAY, JUNE 3<br />
531<br />
Balloon Catheter-Mediated Hepatic Vein Delivery <strong>of</strong> a<br />
Viral Vector Mitigates Neutralization by Anti-Viral<br />
Antibodies and Results in Efficient Transduction <strong>of</strong><br />
Rabbit Liver<br />
Bradley L. Hodges, Kristin M. Taylor, Qiuming Chu,<br />
Samantha E. Scull, Rebecca G. Serriello, Scott C. Anderson,<br />
Ronald K. Scheule<br />
532<br />
Effects <strong>of</strong> a New YB-1 Dependent Adenovirus (XVir) in<br />
Human Prostate Cancer <strong>Cell</strong> Lines and in a Xenograft<br />
Mouse Model<br />
Klaus Mantwill, Nadia Koehler-Vargas, Alexandra<br />
Bernshausen, Uwe Treiber, Rudolf Hartung, Bernd Gansbacher,<br />
Per Sonne Holm<br />
533<br />
Enhanced Transduction <strong>of</strong> Dendritic <strong>Cell</strong>s by FCgRI-<br />
Targeted Adenovirus Vectorsgð<br />
Ramil E. Sapinoro, Angela P. H. Burgess, Stephen Dewhurst<br />
534<br />
Optimising Expression Cassettes for Vascular <strong>Gene</strong><br />
Expression<br />
Stephen J. White, Melanie A. Roberts, Jeremy R. Sanford, Javier<br />
F. Cáceres, Andrew C. Newby<br />
535<br />
Long-Term Correction <strong>of</strong> Hyperbilirubinemia in a Rat<br />
Model <strong>of</strong> Crigler-Najjar Syndrome Type 1<br />
Viraj P. Mane, Gabriele Toietta, Wilma Norona, Milton<br />
Finegold, Phil Ng, Arthur L. Beaudet, Anthony F. McDonagh,<br />
Brendan Lee<br />
536<br />
Adenoviral Vector-Mediated <strong>Gene</strong> <strong>Therapy</strong> for<br />
Adenocortical Carcinoma: Therapeutic Strategies and<br />
Safety Considerations<br />
Luisa Barzon, Urska Trost, Monia Pacenti, Anna-Lisa Stefani,<br />
Marta Trevisan, Giulia Masi, Karina Fincati, Giorgio Palù<br />
537<br />
Transcriptionally Targeting the Survivin Promoter to<br />
Human Gliomas<br />
Zeng B. Zhu, Winan J. Houdt, Yosef S. Haviv, Baogen Lu,<br />
Minghui Wang, Angel A. Rivera, Ilya V. Ulasov, Maciej S.<br />
Lesniak, <strong>Gene</strong> P. Siegal, Clemens M. F. Dirven David T.<br />
Curiel<br />
538<br />
Fiber Chimeric Oncolytic Adenoviral Vectors Mediate<br />
Efficient <strong>Gene</strong> Transfer and Oncolysis <strong>of</strong> Head and Neck<br />
Cancer and Melanoma <strong>Cell</strong>s In Vitro and In Vivo<br />
Shanthi Ganesh, Yuanhao Li, Peter Working, P. Seshidhar<br />
Reddy, De-Chao Yu<br />
539<br />
Antitumor Activity <strong>of</strong> an hTERT-Specific, GFP Expressing<br />
Oncolytic Adenovirus<br />
John J. Davis, Li Wang, Lidong Zhang, Wei Guo, Fuminori<br />
Teraishi, Kai Xu, Lin Ji, Bingliang Fang<br />
540<br />
Re-Targeting <strong>of</strong> Adenoviral Vector-Mediated Interferongð<br />
<strong>Gene</strong> Transfer to Colon Cancer <strong>Cell</strong>s That Express the<br />
Human Carcinoembryonic Antigen<br />
Maaike Everts, Jing Li, Krishnakant Pondugula, Angel A.<br />
Rivera, David T. Curiel, J. Michael Mathis<br />
541<br />
Oncolytic Effects <strong>of</strong> Conditionally Replicating<br />
Adenoviruses (CRAds) with Mutations in E1A and E1B<br />
Regions<br />
Hyunhee Kim, Jaesung Kim, Kyung-Ju Choi, Pyung Hwan<br />
Kim, Tae Young Koo, Ahmed M. Al-Abd, Hye Jin Choi, Joo-<br />
Hang Kim, Chae-Ok Yun<br />
542<br />
Targeting EGFR with Metabolically Biotinylated Fiber-<br />
Mosaic Adenovirus<br />
Larisa Pereboeva, Svetlana Komarova, Selvarangan<br />
Ponnazhagan, David T. Curiel<br />
543<br />
Enhanced Glia-Specific Expression Using GFAP-<br />
’Super’Promoters in an Adenoviral Context In Vitro and<br />
In Vivo<br />
Bertie de Leeuw, Maarten ter Horst, Mark Rodijk, Rob C.<br />
Hoeben, Michael Brenner, Peter A. E. Sillevis Smitt<br />
544<br />
Interferon alpha-2b <strong>Gene</strong> Delivery for Bladder Cancer<br />
Demonstrates Feasibility <strong>of</strong> Repeated Intravesical Dosing<br />
with an Adenovirus Vector<br />
Heidrun Engler, Robert J. Connor, Jennifer M. Anderson, Drake<br />
LaFace, Daniel C. Maneval<br />
545<br />
Adenovirus Mediated <strong>Gene</strong> Transfer and Oncolysis In<br />
Vitro in Head and Neck Cancer and Melanoma <strong>Cell</strong>s<br />
Enhanced by Polycations<br />
Lian Mo, Gary Lee, Shanthi Ganesh, Yuanhao Li, Peter<br />
Working, P. Seshidhar Reddy, De-Chao Yu<br />
546<br />
<strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Ovarian Cancer by IAI.3B Promoter<br />
Driven Oncolytic Adenovirus<br />
Katsuyuki Hamada, Toshiro Shirakawa, Akinobu Gotoh<br />
547<br />
Improvement <strong>of</strong> Liver <strong>Gene</strong> Transfer by First and Third<br />
<strong>Gene</strong>ration Adenoviral Vectors<br />
Julien S. Crettaz, Pedro Berraondo, Itsaso Mauleon, Laura<br />
Ochoa, Veijay Shankar, Miguel Barajas, Maider Zabala, Nico<br />
van Rooijen, Stefan Kochanek, Cheng Qian Jesus Prieto, Ruben<br />
Hernandez-Alcoceba, Gloria Gonzalez-Aseguinolaza