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FINAL PROGR AM - American Society of Gene & Cell Therapy

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74<br />

8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />

ABSTRACTS<br />

FRIDAY, JUNE 3<br />

463 4:15 PM<br />

Efficient Lentiviral <strong>Gene</strong> Transfer and Expression in<br />

Human Embryonic Stem <strong>Cell</strong>s<br />

Carolyn Lutzko, XiaoJin Yu, Dinithi Senadheera, Donald B.<br />

Kohn<br />

Oral Abstract Session 338<br />

<strong>Gene</strong> Regulation: Regulated Systems and <strong>Cell</strong><br />

Engineering<br />

Room: 261/262<br />

464 2:00 PM<br />

Development <strong>of</strong> a Novel <strong>Gene</strong> Regulation System<br />

Downstream <strong>of</strong> Promoter<br />

Hongzhe Duan, Chengwen Li, Richard Jude Samulski<br />

465 2:15 PM<br />

In Vivo Selection <strong>of</strong> <strong>Gene</strong>tically Modified Primary<br />

Human Hematopoietic <strong>Cell</strong>s Using a <strong>Cell</strong> Growth<br />

Switch<br />

Linlin Wang, Yasuo Nagasawa, Brent Wood, Ingrid Lintmaer,<br />

Thalia Papayannopoulou, Michael Harkey, Cynthia Nougirat,<br />

C. Anthony Blau<br />

466 2:30 PM<br />

Long-Term Rapamycin Control <strong>of</strong> Transgene Expression<br />

in Mouse Salivary Glands in a Single AAV Vector<br />

Jianghua Wang, Antonis Voutetakis, Milton Papa, Victor M.<br />

Rivera, Tim Clackson, Beatrijs M. Lodde, Fumi Mineshiba,<br />

Bruce J. Baum<br />

467 2:45 PM<br />

Allogeneic Bone-Marrow Transplantation in Mice<br />

Provides Tolerance and Promotes Massive In Vivo<br />

Selection <strong>of</strong> Subsequently Transplanted Hepatocytes<br />

Konrad L. Streetz, Regis Doyonnas, Denny D. Jenkins, Seppi<br />

Lin, Judith A. Shizuru, Helen Blau, Karl Sylvester, Mark A.<br />

Kay<br />

468 3:00 PM<br />

<strong>Cell</strong>ular <strong>Therapy</strong> with Transgene Expressing APC<br />

Activates CD4+CD25+ Regulatory T <strong>Cell</strong>s Which<br />

Modulate the Immune Response to <strong>Gene</strong> <strong>Therapy</strong><br />

Derived Products in Immunocompetent Mice<br />

Andrea Annoni, Manuela Battaglia, Antonia Follenzi, Angelo<br />

Lombardo, Luigi Naldini, Maria Grazia Roncarolo<br />

469 3:15 PM<br />

Induction <strong>of</strong> Donor Specific Tolerance Using <strong>Gene</strong><br />

<strong>Therapy</strong> and Sublethal Conditioning<br />

Daron Forman, Chaorui Tian, John Iacomini<br />

470 3:30 PM<br />

Foamy Viral Mediated Transduction <strong>of</strong> Recombinant<br />

FANCC in the Absence <strong>of</strong> Prestimulation Is Sufficient To<br />

Restore the Long Term Repopulating Activity <strong>of</strong> Fancc -/-<br />

Stem <strong>Cell</strong>s and Prevent the Acquisition <strong>of</strong> Myeloid<br />

Malignancies<br />

Yue Si, Cordula Leurs, Edward F. Srour, Jin Yuan, Helmut<br />

Hanenberg, D. Wade Clapp<br />

471 3:45 PM<br />

Microvessel Injury and Irradiation Damage in Salivary<br />

Glands<br />

Ana Paola P. Cotrim, Jianghua Wang, Antonis Voutetakis,<br />

Anastasia L. Sowers, James B. Mitchell, Bruce J. Baum<br />

472 4:00 PM<br />

Hematopoietic <strong>Cell</strong> Differentiation from Common<br />

Marmoset (Callithrix jacchus) Embryonic Stem <strong>Cell</strong>s by<br />

Their <strong>Gene</strong>tic Manipulation Using the Third <strong>Gene</strong>ration<br />

Lentiviral Vector<br />

Tomoko Yokoo, Ryo Kurita, Erika Sasaki, Takashi Hiroyama,<br />

Yukoh Nakazaki, Kiyoko Izawa, Hajime Ishii, Yoshikuni<br />

Tanioka, Kisaburo Hanazawa, Yuan Son Bai Yasushi Soda,<br />

Kenzaburo Tani<br />

473 4:15 PM<br />

Definitive Identification and Isolation <strong>of</strong> Embryonic<br />

Stem <strong>Cell</strong>-Derived Target <strong>Cell</strong>s by Adenoviral Conditional<br />

Targeting; Efficient Purification <strong>of</strong> Immature and<br />

Mature <strong>Cell</strong>s in the Cardiac Lineage<br />

Ken-ichiro Kosai, Tomoyuki Takahashi<br />

Poster Session II<br />

Exhibit Hall 2<br />

RNA Virus Vectors: <strong>Gene</strong> Transfer, Vector Production<br />

474<br />

Transduction <strong>of</strong> Minimally Stimulated Hematopoietic<br />

Progenitor <strong>Cell</strong>s with a Foamy Virus Vector That Expresses<br />

MGMTP140K Shanbao Cai, Jennifer R. Hartwell, Aaron G. Ernstberger, W. S.<br />

Goebel, Helmut Hanenberg, Karen E. Pollok<br />

475<br />

In Vivo Targeting <strong>of</strong> MLV(HIV) Pseudotype Vectors to T<br />

Lymphocytes in a Transgenic Mouse Model<br />

Silke Schuele, Stefanie Steidl, Sylvia Raupp, Cheick Coulibaly,<br />

Ulrich Kalinke, Klaus Cichutek, Matthias Schweizer<br />

476<br />

HIV-1 and HIV-2 Chimeric Lentiviral Vectors for <strong>Gene</strong><br />

Transfer<br />

Geetanjali Sachdeva, Kritika Kachapati, Suresh Arya

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