FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 73<br />
ABSTRACTS<br />
FRIDAY, JUNE 3<br />
447 2:45 PM<br />
Mesenchymal Stem <strong>Cell</strong>s as Delivery Systems for Cancer<br />
<strong>Therapy</strong>: Evaluation <strong>of</strong> Tropism and Efficacy<br />
Frank Marini, Jennifer Dembinski, Matus Studeny, Claudia<br />
Zompetta, Michael Andreeff<br />
448 3:00 PM<br />
A <strong>Gene</strong>tic Strategy to Inhibit Complement Activation<br />
Arising from Adenoviral Vectors<br />
Kurt R. Zinn, Hongju Wu, Amanda Stargel, April J. Adams,<br />
Tandra R. Chaudhuri<br />
449 3:15 PM<br />
Tumor Targeted, Systemic Delivery <strong>of</strong> Therapeutic Viral<br />
Vectors Using Hitch Hiking on Antigen Specific T <strong>Cell</strong>s<br />
Jian Qiao, Caroline Cole, Timothy Kottke, Rosa Maria Diaz,<br />
Luis Sanchez-Perez, Gregory Brunn, Jill Thompson, Richard<br />
Vile<br />
450 3:30 PM<br />
Combination <strong>of</strong> Fas <strong>Gene</strong> <strong>Therapy</strong> and Ceramide<br />
Analogues: A Double Edge Sword for the Treatment <strong>of</strong><br />
Head and Neck Cancer<br />
Saeed N. Elojeimy, John C. McKillop, Ahmed M. El-Zawahry,<br />
David A. Schwartz, David H. Holman, Xiang Liu, Terry Day,<br />
Alicja Bielawska, Yusuf A. Hannun, James S. Norris<br />
451 3:45 PM<br />
Matrix Metalloproteinase-Targeted Oncolytic Sendai<br />
Virus Vector “Armed” with a Sucide <strong>Gene</strong> “Yeast Cytosine<br />
Deaminase”; Remarkable Combinational Effects<br />
Hiroaki Kinoh, Makoto Inoue, Kentaro Washizawa, Eiji Akiba,<br />
Mamoru Hasegawa<br />
452 4:00 PM<br />
The Enhancement <strong>of</strong> Anticancer Effect <strong>of</strong> Chemotherapy<br />
by the Delivery <strong>of</strong> Rad51 siRNA<br />
Makoto Ito, Seiji Yamamoto, Keisuke Nimura, Katsuto Tamai,<br />
Yasufumi Kaneda<br />
453 4:15 PM<br />
The Histone Deacetylase Inhibitor FK228 Can Increase<br />
Adenovirus Transgene Protein Expression in Human<br />
LOX IMVI Melanoma Xenografts<br />
Merrill E. Goldsmith, Alian Aguila, Michael C. Alley, William<br />
R. Waud, Susan Bates, Tito Fojo<br />
Oral Abstract Session 337<br />
Advances in Hematologic <strong>Gene</strong> <strong>Therapy</strong><br />
Room: 263/267<br />
454 2:00 PM<br />
Mouse Models for the Analysis <strong>of</strong> <strong>Gene</strong>tic Risk Factors<br />
for Hematopoietic Transformation in XSCID <strong>Gene</strong><br />
<strong>Therapy</strong><br />
Yan Shou, Lilia Stepanova, Brian P. Sorrentino<br />
455 2:15 PM<br />
Drug Resistance <strong>Gene</strong> <strong>Therapy</strong> to Induce Donor-Specific<br />
Tolerance after Nonmyeloablative Allogeneic Stem <strong>Cell</strong><br />
Transplantation in Dogs<br />
Sabine Gerull, Karen E. Beagles, Brian C. Beard, Laura J.<br />
Peterson, Hans-Peter Kiem<br />
456 2:30 PM<br />
HOXB4 Overexpression Expands Short-Term Repopulating<br />
<strong>Cell</strong>s in Nonhuman Primates and Dogs<br />
Xiao-Bing Zhang, Laura J. Peterson, Alixandra A. Knapp,<br />
Brian C. Beard, R. Keith Humphries, Hans-Peter Kiem<br />
457 2:45 PM<br />
The Benefits <strong>of</strong> CH-296 during Ex Vivo <strong>Gene</strong> Transfer<br />
Go beyond the Ability to Co-Localize the Retroviral<br />
Particle and Target <strong>Cell</strong><br />
Mo A. Dao, Jan A. Nolta<br />
458 3:00 PM<br />
Reversal <strong>of</strong> Canine Leukocyte Adhesion Deficiency by<br />
Retroviral-Vector Mediated <strong>Gene</strong> <strong>Therapy</strong> with Non-<br />
Myeloablative Conditioning<br />
Thomas R. Bauer, Jr., Laura M. Tuschong, Mehreen Hai, Yuchen<br />
Gu, Robert A. Sokolic, Tanya Burkholder, John D. Bacher,<br />
Dennis D. Hickstein<br />
459 3:15 PM<br />
Long-Term Treatment <strong>of</strong> Canine Cyclic Neutropenia by<br />
G-CSF-Lentivirus<br />
William Osborne, Margaret Brzezinski, Ofer Yanay, Lanaya<br />
Waldon, Jeffrey Christensen, Denny Liggitt, David Dale<br />
460 3:30 PM<br />
Transplantation <strong>of</strong> Human Aldehyde Dehydrogenase<br />
Expressing <strong>Cell</strong>s Leads to Widespread Tissue Distribution<br />
<strong>of</strong> Donor <strong>Cell</strong>s in the Pancreas and Liver <strong>of</strong> NOD/SCID/<br />
MPSVII Mice<br />
David A. Hess, Timothy P. Craft, Louisa Wirthlin, Phillip E.<br />
Herrbrich, Alex A. H<strong>of</strong>ling, Mark S. Sands, Jan A. Nolta<br />
461 3:45 PM<br />
Qualitative and Quantitative Luciferase Expression In<br />
Vivo <strong>of</strong> Transduced Hematopoietic <strong>Cell</strong> populations<br />
Using Bioluminescent Imaging (BLI)<br />
Henk Rozemuller, Ingrid F. H. Koggel, Robbert Spaapen, Anton<br />
Hagenbeek, Anton C. M. Martens<br />
462 4:00 PM<br />
Busulfan Dose Escalation to Increase <strong>Gene</strong> Marking <strong>of</strong><br />
Hematopoietic Stem <strong>Cell</strong>s by Lentiviral Vectors in Infant<br />
Rhesus Monkeys<br />
Christoph A. Kahl, Alice F. Tarantal, Chang I. Lee, Daniel F.<br />
Jimenez, Christopher Choi, Karen Pepper, Denise Peterson,<br />
Misty D. Fletcher, Alyssa C. Leapley, Donald B. Kohn
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