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FINAL PROGR AM - American Society of Gene & Cell Therapy

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50<br />

8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />

ABSTRACTS<br />

THURSDAY, JUNE 2<br />

63 2:30 PM<br />

A Nonhuman Primate Model for Testing Immuno <strong>Gene</strong><br />

Therapies for AIDS Using <strong>Gene</strong>-Protected T <strong>Cell</strong>s<br />

Joern E. Schmitz, Felix Hermann, Sebastian Newrzela, Melisa<br />

Ricketts, Patricia Schult-Dietrich, Alexander Szyroki, Robert P.<br />

Johnson, Dorothee von Laer<br />

64 2:45 PM<br />

Characterization <strong>of</strong> the Mechanism <strong>of</strong> Action <strong>of</strong> the Anti-<br />

HIV-1 Transgene F12-Vif<br />

Rossella Lupo, Giuliana Vallanti, Maurizio Federico, Fulvio<br />

Mavilio, Chiara Bovolenta<br />

65 3:00 PM<br />

Protective Immunity Against Anthrax Lethal Toxin in<br />

Mice Immunized with an Ad-Based Vaccine Vector<br />

Expressing Lethal Factor<br />

Julie L. Boyer, Tiffany B. Niven, Neil R. Hackett, Ronald G.<br />

Crystal<br />

66 3:15 PM<br />

A Protective Vaccine for the Rapid Response to Pandemic<br />

AVian Influenza<br />

Wentao Gao, Adam Sol<strong>of</strong>f, Xiuhua Liu, Angela Montecalvo,<br />

Yumiko Matsuoka, Paul D. Robbins, Ruben O. Donis,<br />

Jacqueline M. Katz, Simon Barratt-Boyes, Andrea Gambotto<br />

67 3:30 PM<br />

Protective Immunity Against Yersinia pestis in Mice<br />

Immunized with an Ad-Based Vaccine Vector Expressing<br />

the Y. pestis F1 and V Antigens<br />

Maria Chiuchiolo, Julie L. Boyer, Tiffany Niven, Anja Krause,<br />

Neil R. Hackett, Ronald G. Crystal<br />

68 3:45 PM<br />

Development <strong>of</strong> a Novel Non-Viral DNA Vaccine-<br />

Delivering <strong>Gene</strong> into the Nucleus <strong>of</strong> Dendritic <strong>Cell</strong>s<br />

Takashi Nakamra, Kentaro Kogure, Rumiko Moriguchi, Shiroh<br />

Futaki, Masahiro Fujimuro, Hideyoshi Yokosawa, Tsukasa<br />

Seya, Hideyoshi Harashima<br />

Oral Abstract Session 247<br />

Cancer-Targeted <strong>Gene</strong> <strong>Therapy</strong>: Non Adenoviral<br />

Targeting <strong>of</strong> Vectors and Non Viral Vectors<br />

Room: 265/266<br />

69 2:00 PM<br />

Tumor-Targeting Innumogene <strong>Therapy</strong> by Mesenchymal<br />

Stem <strong>Cell</strong>s Expressing CX3CL1<br />

Hong Xin, Masahiko Kanehira, Hiroyuki Mizuguchi, Takao<br />

Hayakawa, Toshihiro Nukiwa, Yasuo Saijo<br />

70 2:15 PM<br />

Systemic Administration <strong>of</strong> siRNA Against EWS-FLI1<br />

Using a Targeted, Non-Viral Formulation Inhibits<br />

Growth in a Disseminated Murine Model <strong>of</strong> Ewing’s<br />

Sarcoma<br />

Jeremy D. Heidel, Siwen Hu-Lieskovan, Derek W. Bartlett,<br />

Timothy J. Triche, Mark E. Davis<br />

71 2:30 PM<br />

Intratumoral Delivery <strong>of</strong> Small Interfering RNA for<br />

Inhibition <strong>of</strong> Tumor Progression in Mice<br />

Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura<br />

72 2:45 PM<br />

Capsid Modifications Overcome Low Heterogeneous<br />

Expression <strong>of</strong> Heparan Sulfate Proteoglycan That Limits<br />

AAV2-Mediated <strong>Gene</strong> Transfer and Therapeutic Efficacy<br />

in Human Ovarian Carcinoma<br />

Jeffrey S. Bartlett, Wenfang Shi<br />

73 3:00 PM<br />

Fully Retargeted Oncolytic Measles Viruses for Cancer<br />

<strong>Therapy</strong><br />

Takafumi Nakamura, Mary Harvey, Suzanne Greiner, Kah-<br />

Whye Peng, Stephen J. Russell<br />

74 3:15 PM<br />

Specific Delivery <strong>of</strong> hTRAIL and Inhibition <strong>of</strong> Ewing’s<br />

Sarcoma Growth by Transplantation <strong>of</strong> Viral Vector-<br />

Transduced Bone Marrow-Derived Mesenchymal Stem<br />

<strong>Cell</strong>s (MSC)<br />

Jeffrey S. Bartlett, Wenfang Shi, Carmel Lawrencia<br />

75 3:30 PM<br />

Molecular Imaging <strong>of</strong> an EGFP-DRD2-Expressing<br />

Vaccinia Virus<br />

Navneet Mehta, Nan Tang, Hui Deng, Deborah Scollard, James<br />

Jonkman, Brian C. Wilson, Raymond M. Reilly, Judith A.<br />

McCart<br />

76 3:45 PM<br />

New Strategy To Improve Imaging and Retargeting <strong>of</strong><br />

HSV-1 Vectors<br />

Paola Grandi, Trevor D. McKee, Wilson Mok, Juliet L.<br />

Fernandez, Xandra O. Breakefield, Rakesh K. Jain<br />

77 4:00 PM<br />

Efficient Transduction and <strong>Therapy</strong> <strong>of</strong> Malignant Glioma<br />

by Lentiviral Vectors Pseudotyped with LCMV Glycoproteins<br />

Hrvoje Miletic, Yvonne Fischer, Harald Neumann, Tsanan<br />

Giroglou, Manuel M. Hermann, Werner Stenzel, Maria A.<br />

Rueger, Yannic Waerzeggers, Uwe Himmelreich, Mathias Hoehn<br />

Andreas H. Jacobs, Martina Deckert, Dorothee von Laer

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