FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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46<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
THURSDAY, JUNE 2<br />
Oral Abstract Session 240<br />
RNA Virus Vectors: <strong>Gene</strong> Transfer and <strong>Gene</strong><br />
Expression<br />
Room: 260/264<br />
1 2:00 PM<br />
Persistent <strong>Gene</strong> Expression in Mouse Nasal Epithelia<br />
Following Baculovirus GP64 Pseudotyped FIV-Based<br />
<strong>Gene</strong> Transfer<br />
Patrick L. Sinn, Erin R. Burnight, Melissa A. Hickey, Gary W.<br />
Blissard, Paul B. McCray, Jr.<br />
2 2:15 PM<br />
<strong>Cell</strong>ular Mechanisms Involved with Lentiviral <strong>Gene</strong><br />
Transfer<br />
Shangming Zhang, Karen Pollok, Lakshmi Sastry, Lionel<br />
Berthoux, Jeremy Luban, Kenneth Cornetta<br />
3 2:30 PM<br />
Effects <strong>of</strong> the cHS4 Insulator Elements on Transgene<br />
Expression and Biological Titer <strong>of</strong> Lentiviral Vector<br />
Hideki Hanawa, Takashi Shimada<br />
4 2:45 PM<br />
Optimization <strong>of</strong> Globin Lentiviral Vector Design for the<br />
Treatment <strong>of</strong> bð-Thalassemia<br />
Leszek Lisowski, Stefano Rivella, Michel Sadelain<br />
5 3:00 PM<br />
Differential Expression <strong>of</strong> PIT1 and PIT2 after G-CSF<br />
Mobilization Is Associated with Efficient <strong>Gene</strong> Transfer<br />
Using GALV-Pseudotyped Gammaretroviral Vectors<br />
Brian C. Beard, Pau Mezquita, Julia C. Morris, Hans-Peter<br />
Kiem<br />
6 3:15 PM<br />
In Vivo Adult Stem <strong>Cell</strong> <strong>Gene</strong> Transfer in Mice by In Situ<br />
Delivery <strong>of</strong> a Self-Inactivating Lentiviral Vector Using<br />
Intrafemoral Injection<br />
D. Nicole Worsham, Kimberly Bohn, David Kuhel, David A.<br />
Williams, Christ<strong>of</strong> von Kalle, Dao Pan<br />
7 3:30 PM<br />
Transduction <strong>of</strong> Quiescent Human <strong>Cell</strong>s Using an<br />
SIVsmmPBj-Derived Lentiviral Vector<br />
Matthias Schweizer, Nina Wolfrum, Michael Muehlebach, Julia<br />
Kaiser, Silke Schuele, Klaus Cichutek<br />
8 3:45 PM<br />
Potent Inhibition <strong>of</strong> HIV-1 Replication by Lentiviral<br />
Vectors Carrying Anti-Vif siRNA<br />
S. Li, G. Wang, K. Meinking, M. J. Li, J. Ji, J. A. Zaia, J. J.<br />
Rossi<br />
9 4:00 PM<br />
Coronaviruses: Development <strong>of</strong> Novel Oncolytic Vectors<br />
Tom Würdinger, Hélène M. Verheije, Victor W. van Beusechem,<br />
Xander A. M. de Haan, Winald R. Gerritsen, Peter J. M. Rottier<br />
10 4:15 PM<br />
The Effect <strong>of</strong> Globin Locus Control Region (LCR)<br />
Elements or the MSCV-LTR on Promoter Trapping by<br />
Integrated Lentiviral Vector Genomes<br />
Byoung Y. Ryu, Derek A. Persons, Arthur W. Nienhuis<br />
Oral Abstract Session 241<br />
AAV Vectors: Vector Biology<br />
Room: 240 Complex<br />
11 2:00 PM<br />
An Additional Role <strong>of</strong> <strong>Cell</strong>ular FKBP52 in Recombinant<br />
Adeno-Associated Virus 2 Vector-Mediated <strong>Gene</strong><br />
Transfer and Transgene Expression<br />
Weihong Zhao, Li Zhong, Jianqing Wu, Liyuan Chen, Keyun<br />
Qing, Kirsten A. Weigek-Kelley, Steven H. Larsen, Arun<br />
Srivastava<br />
12 2:15 PM<br />
Self-Complementary AAV2 Vectors Transduce Liver with<br />
the Same Efficiency as AAV8: The Critical Role <strong>of</strong><br />
Second-Strand Synthesis in AAV Biology<br />
Zhijian Wu, Hongzhe Duan, R. Jude Samulski<br />
13 2:30 PM<br />
Persistence <strong>of</strong> AAV Capsid in Transduced <strong>Cell</strong>s<br />
Mo-Ying Hsieh, Fayaz R. Khazi, Alexander Schlachterman, Yi-<br />
Lin Liu, Katherine A. High<br />
14 2:45 PM<br />
rAAV2 Integration Junctions Isolated without In Vivo<br />
Selection Bias Show a Preference to 5’ Regions <strong>of</strong> Open<br />
Reading Frames<br />
Fayaz R. Khazi, Alexander Schlachterman, Katherine A. High<br />
15 3:00 PM<br />
Large-Scale Analysis <strong>of</strong> Adeno-Associated Virus Vector<br />
Integration Sites in Normal Human <strong>Cell</strong>s<br />
Daniel G. Miller, Grant D. Trobridge, Lisa M. Petek, Michael<br />
A. Jacobs, Rajinder Kaul, David W. Russell<br />
16 3:15 PM<br />
Single-Polarity Recombinant Adeno-Associated Virus 2<br />
Vector-Mediated Transgene Expression In Vitro and In<br />
Vivo: Mechanism <strong>of</strong> Transduction<br />
Li Zhong, Xiaohuai Zhou, Yanjun Li, Keyun Qing, Richard J.<br />
Samulski, Arun Srivastava<br />
17 3:30 PM<br />
Visualization <strong>of</strong> the Intranuclear rAAV Replication<br />
Centers and Their Co-Localization with Double-<br />
Stranded DNA Break Repair Proteins<br />
Cervelli Tiziana, Lorena Zentilin, Alessandro Marcello, Mauro<br />
Giacca
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