FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 115<br />
ABSTRACTS<br />
SUNDAY, JUNE 5<br />
1127 12:00 PM<br />
Perivascular CD45 - :Sca-1 + :CD34 - <strong>Cell</strong>s Are Derived<br />
from Bone Marrow <strong>Cell</strong>s and Participate in Dystrophic<br />
Skeletal Muscle Regeneration<br />
Sheng Li, Morayma Reyes, En Kimura, Jessica Foraker, Miki<br />
Hagakura, Leonard Meuse, Brent Fall, Jeffrey S. Chamberlain<br />
Oral Abstract Session 517<br />
Cancer - Immunotherapy: <strong>Gene</strong>tic Strategies to Induce<br />
and Augment Anti-Tumor Immunity<br />
Room: 123/127<br />
1128 10:15 <strong>AM</strong><br />
Ad-sig-TAA/ecdCD40L Vector Prime, TAA/CD40L<br />
Protein Boost Vaccine Breaks Tolerance for Tumor<br />
Assoicated Antigens (TAA) and Suppresses Growth and<br />
Metastasis <strong>of</strong> Epithelial Neoplastic <strong>Cell</strong>s<br />
Yucheng Tang, Jonathan Maynard, Xiang Ming Fang, Wei Wei<br />
Zhang, Albert Deisseroth<br />
1129 10:30 <strong>AM</strong><br />
Ad.Interferon Beta Is an Effective Treatment in an<br />
Orthotopic Model <strong>of</strong> Broncho-Alveolar Non-Small <strong>Cell</strong><br />
Lung Cancer Via NK <strong>Cell</strong> and CD 8+ T <strong>Cell</strong> Mechanisms<br />
Michael J. Wilderman, Jin Sun, Anil Vachani, Eiji Suzuki,<br />
Dan H. Sterman, Larry R. Kaiser, Steve M. Albelda<br />
1130 10:45 <strong>AM</strong><br />
A Single-Component CD40-Targeted Adenoviral Vector<br />
for Efficient Transduction and Activation <strong>of</strong> Cutaneous<br />
Dendritic <strong>Cell</strong>s<br />
Nikolay Korokhov, Sam C. Noureddini, David T. Curiel,<br />
Saskia J. A. M. Santegoets, Rik J. Scheper, Tanja D. de Gruijl<br />
1131 11:00 <strong>AM</strong><br />
<strong>Gene</strong>ration <strong>of</strong> Whole <strong>Cell</strong> Vaccines for Acute Myeloid<br />
Leukaemia by Lentivirus Mediated IL-2/CD80 Transduction<br />
Lucas Chan, Nicola Hardwich, Dave Darling, Joop Gäken,<br />
Joanna Galea-Lauri, Steve Devereux, Ghulam Mufti, Farzin<br />
Farzaneh<br />
1132 11:15 <strong>AM</strong><br />
Role <strong>of</strong> Akt in Dendritic <strong>Cell</strong> (DC) Survival and Application<br />
<strong>of</strong> an Akt “LIFE SWITCH” in DC-Based Tumor<br />
Vaccines<br />
Dongsu Park, Mamatha R. Seethammagari, David M. Spencer<br />
1133 11:30 <strong>AM</strong><br />
A Phase I Study <strong>of</strong> Antitumor Vaccination Using <strong>Gene</strong>tically<br />
Modified Tumor <strong>Cell</strong>s Expressing<br />
α(1,3)Galactosyltransferase in Patients with Refractory or<br />
Recurrent Non-Small <strong>Cell</strong> Lung Cancer (NSCLC):<br />
Preliminary Results<br />
John C. Morris, John E. Janik, Nicholas Vahanian, Leslie<br />
Moses, Diana O’Hagan, Lucinda Tennant, Stefania Pittaluga,<br />
Wendy Gao, Paul Albert, Tatiana Seregina Charles J. Link<br />
1134 11:45 <strong>AM</strong><br />
Intratumoral Injection <strong>of</strong> Dendritic <strong>Cell</strong>s Engineered to<br />
Secrete Interleukin-12 by Recombinant Adenovirus in<br />
Patients with Metastatic Gastrointestinal Carcinomas<br />
Guillermo D. Mazzolini, Carlos Alfaro, Bruno Sangro,<br />
Esperanza Feijoo, Juan Ruiz, Alberto Benito, Inigo Tirapu,<br />
Ainhoa Arina, Josu Sola, Maite Herraiz Felipe Lucena, Cristina<br />
Olague, Jose Subtil, Jorge Quiroga, Ignacio Herrero, Belen<br />
Sadaba, Maurizio Bendandi, Cheng Qian, Jesus Prieto, Ignacio<br />
Melero<br />
1135 12:00 PM<br />
Results <strong>of</strong> a Phase I/II Clinical Trial with OncoVEXGM-CSF ,<br />
a Second <strong>Gene</strong>ration Oncolytic Herpes Simplex Virus<br />
J. C. Hu, R. S. C<strong>of</strong>fin, C. J. Davis, N. J. Graham, N. Groves,<br />
P. J. Guest, K. J. Harrington, N. D. James, C. A. Love, I.<br />
McNeish L. C. Medley, A. Michael, C. M. Nutting, H. S.<br />
Pandha, C. A. Shorrock, J. Simpson, J. Steiner, N. M. Steven,<br />
R. C. Coombes
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