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FINAL PROGR AM - American Society of Gene & Cell Therapy

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114<br />

8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />

ABSTRACTS<br />

SUNDAY, JUNE 5<br />

Oral Abstract Session 515<br />

Cardiovascular: Angiogenesis and Vascular <strong>Gene</strong><br />

<strong>Therapy</strong><br />

Room: 261/262<br />

1112 10:15 <strong>AM</strong><br />

The Treatment with Intra Muscular (IM) Vascular<br />

Endothelial Growth Factor (VEGF) <strong>Gene</strong> Compared<br />

with Placebo for Patients with Diabetes Mellitus and<br />

Critical Limb Ischemia (CLI), a Double Blind Phase III<br />

Study<br />

Yoka H. Kusumanto, Vincent Weel, Nanno H. Mulder, Andries<br />

J. Smit, Jan J. Dungen, Anneke M. Hooymans, Wim J. Sluiter,<br />

Rene A. Tio, Paul H. Quax, Rijk O. Gans Robin P. Dullaart,<br />

Geke A. Hospers<br />

1113 10:30 <strong>AM</strong><br />

Spliceosome Mediated RNA Trans-Splicing (SMaRT)<br />

Strategy To Increase the Production <strong>of</strong> Human<br />

Apolipoprotein (ApoA1)<br />

M. Puttaraju, Jun Wang, Alan T. Remaley, Bryan H. Brewer, Jr,<br />

Gerard J. McGarrity, Mariano A. Garcia-Blanco<br />

1114 10:45 <strong>AM</strong><br />

Antithrombotic Effects <strong>of</strong> Endogenous Expressed<br />

Activated Protein C (aPC) in Murine Models<br />

Joerg Schuettrumpf, Alexander Schlachterman, Jianxiang Zou,<br />

Jianhua Liu, Christian Furlan Freguia, Valder R. Arruda<br />

1115 11:00 <strong>AM</strong><br />

Apo A-I and ABCA1 <strong>Gene</strong> Transfer both Increase HDL<br />

Cholesterol but Have Opposing Effects on Progression<br />

<strong>of</strong> Early Atherosclerosis in apo E Deficient Mice<br />

Joke Lievens, Jan Snoeys, Yingmei Feng, Désiré Collen, Bart De<br />

Geest<br />

1116 11:15 <strong>AM</strong><br />

<strong>Gene</strong> Transfert <strong>of</strong> SERCA2a Inhibits Smooth Muscle<br />

Proliferation and Reduce Neointima Formation after<br />

Balloon Injury in the Rat<br />

Larissa Lipskaia, Federica Del Monte, Roger J. Hajjar, Anne-<br />

Marie Lompre<br />

1117 11:30 <strong>AM</strong><br />

<strong>Gene</strong> <strong>Therapy</strong> in a Rat Model <strong>of</strong> Pulmonary Hypertension<br />

Stacy L. Porvasnik, Tankut Onal, Yoshi Sakai, Raquel Torres,<br />

Glenn A. Walter, Barry J. Byrne, Carolyn T. Spencer<br />

1118 11:45 <strong>AM</strong><br />

A Skin <strong>Gene</strong> <strong>Therapy</strong> Approach to Treat Hypertension<br />

Using Long-Term Expression and Systemic Delivery <strong>of</strong><br />

Atrial Natriuretic Peptide (ANP) from the Skin<br />

Jean-Philippe Therrien, Christine L. Tock, Manabu Ohyama,<br />

Jonathan C. Vogel<br />

1119 12:00 PM<br />

Isolation <strong>of</strong> a Novel Therapeutic Angiogenic Peptide,<br />

AG-30, by High Throughput Screening Using the HVJ-E<br />

Vector<br />

Tomoyuki Nishikawa, Hironori Nakagami, Akito Maeda,<br />

Katsuto Tamai, Yasufumi Kaneda<br />

Oral Abstract Session 516<br />

Muscle and Connective Tissue: <strong>Gene</strong> <strong>Therapy</strong> for<br />

Connective Tissue<br />

Room: 230/231<br />

1120 10:15 <strong>AM</strong><br />

Use <strong>of</strong> <strong>Gene</strong> Activated Muscle Grafts for the Repair <strong>of</strong><br />

Large Bone Defects<br />

Volker M. Betz, Oliver B. Betz, Ara Nazarian, Carmencita G.<br />

Pilapil, Mary L. Bouxsein, Louis C. Gerstenfeld, Thomas A.<br />

Einhorn, Mark S. Vrahas, Christopher H. Evans<br />

1121 10:30 <strong>AM</strong><br />

Osteogenic Growth Peptide Preferentially Enhances<br />

Trabecular Bone Mass<br />

Todd E. Meyerrose, Elisheva Smith, Jan A. Nolta, Baruch<br />

Frenkel<br />

1122 10:45 <strong>AM</strong><br />

Transgenic Vasoactive Intestinal Peptide Shows Local<br />

Disease Modifying Effects in a Murine Model <strong>of</strong><br />

Sjögren’s Syndrome<br />

Beatrijs M. Lodde, Fumi Mineshiba, Jianghua Wang, Ana P.<br />

Cotrim, Sandra Afione, Paul P. Tak, Bruce J. Baum<br />

1123 11:00 <strong>AM</strong><br />

Adenovirus-Mediated Expression <strong>of</strong> Sonic Hedgehog<br />

Increases the Number <strong>of</strong> CD34+ <strong>Cell</strong>s in the Epidermal<br />

Stem <strong>Cell</strong> Niche in Hair Follicles<br />

Howard Lou, Andrey Panteleyev, Angela M. Christiano, Ronald<br />

G. Crystal, Philip L. Leopold<br />

1124 11:15 <strong>AM</strong><br />

Correction <strong>of</strong> Glycogen Storage Disease Type II by an<br />

AAV Vector Encoding Highly-Secreted, Chimeric Acid<br />

að-glucosidase<br />

Baodong Sun, Talmage Brown, Andrew Bird, Ayn Schneider,<br />

Sarah P. Young, Alison McVie-Wylie, Y.-T. Chen, Dwight D.<br />

Koeberl<br />

1125 11:30 <strong>AM</strong><br />

AAV-Mediated Myostatin Propeptide <strong>Gene</strong> Delivery<br />

Results in Growth and Hypertrophy <strong>of</strong> Skeletal but Not<br />

Cardiac Muscles<br />

Chunping Qiao, Jianbin Li, Tong Zhu, Chunlian Chen, Terry<br />

O’Day, Jon Watchko, Juan Li, Xiao Xiao<br />

1126 11:45 <strong>AM</strong><br />

Further Characterization <strong>of</strong> Msx1 De-Differentiated<br />

<strong>Cell</strong>s<br />

Qiang Liu, Wen Liu, Yaming Wang

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