FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 113<br />
ABSTRACTS<br />
SUNDAY, JUNE 5<br />
Oral Abstract Session 513<br />
Naked DNA <strong>Gene</strong> Transfer: Chromosomal Integration<br />
Room: 263/267<br />
1096 10:15 <strong>AM</strong><br />
Physical Determinants for Efficient Hydrodynamic <strong>Gene</strong><br />
Delivery to Liver<br />
Takeshi Suda, Regis Vollmer, Dexi Liu<br />
1097 10:30 <strong>AM</strong><br />
Complete and Persistent Phenotypic Correction <strong>of</strong><br />
Phenylketonuria in Mice by Site-Specific Genome<br />
Integration <strong>of</strong> Phenylalanine Hydorxylase cDNA<br />
Li Chen, Savio L. C. Woo<br />
1098 10:45 <strong>AM</strong><br />
Duration <strong>of</strong> Expression <strong>of</strong> Sleeping Beauty Transposase by<br />
Hydrodynamic Injection <strong>of</strong> C57/BL6 Mice<br />
Jason B. Bell, Elena L. Aronovich, Beth E. Larson-DeBruzzi,<br />
Brenda L. Koniar, Roland Gunther, Chester B. Whitley, R.<br />
Scott McIvor, Perry B. Hackett<br />
1099 11:00 <strong>AM</strong><br />
Beyond LoxP: Defining Functional Lox-Like Sequences<br />
for the Cre Recombinase<br />
Jamie E. Sheren, Elizabeth Ketner, Jarred Keith, Stephen J.<br />
Langer, Leslie A. Leinwand<br />
1100 11:15 <strong>AM</strong><br />
Site-Specific Transposon Integration<br />
Joseph M. Kaminski, Maragatha Vally, Todd Tenenholz, James<br />
B. Summers, Craig J. Coates<br />
1101 11:30 <strong>AM</strong><br />
Fusion Proteins Consisting <strong>of</strong> the Sleeping Beauty<br />
Transposase and the Polydactyl Zinc Finger Protein E2C<br />
Direct Transposon Integration into a Unique Human<br />
Chromosomal Sequence<br />
Stephen R. Yant, Yong Huang, Mark A. Kay<br />
1102 11:45 <strong>AM</strong><br />
Stable, Non-Viral <strong>Gene</strong> Transfer to Human CD34 +<br />
Hematopoietic Progenitor <strong>Cell</strong>s Using the Sleeping<br />
Beauty Transposon<br />
Sarah Nightingale, Roger P. Hollis, Karen Pepper, Donald B.<br />
Kohn<br />
1103 12:00 PM<br />
Site-Specific Chromosomal Integration in Human<br />
Mesenchymal Stem <strong>Cell</strong>s Mediated by PhiC31 Integrase<br />
Annahita Keravala, Juergen Hoelters, Sohail Jarrahian, Thomas<br />
W. Chalberg, Marisa Ciccarella, Peter Neth, Michele P. Calos<br />
Oral Abstract Session 514<br />
Molecular Conjugates: Vector Engineering<br />
Room: 265/266<br />
1104 10:15 <strong>AM</strong><br />
Imaging <strong>of</strong> sec-R Directed and PEG-Stabilized <strong>Gene</strong><br />
Transfer Nanoparticles in CF Mice<br />
Maxwell Kotlarchyk, Zhenghong Lee, Mark Cooper, Pamela B.<br />
Davis, Assem G. Ziady<br />
1105 10:30 <strong>AM</strong><br />
DQAsomes Deliver Mitochondrial Leader Peptide<br />
Conjugates <strong>of</strong> Plasmid and Linear Double-Stranded<br />
DNA into Mitochondria within Living Mammalian <strong>Cell</strong>s<br />
Gerard G. M. D’Souza, Sarathi V. Boddapati, Robert N.<br />
Lightowlers, Volkmar Weissig<br />
1106 10:45 <strong>AM</strong><br />
Development and Testing <strong>of</strong> Ternary Peptide Copolymerized<br />
<strong>Gene</strong> Delivery Systems<br />
Changpo Chen, Ji-seon Kim, Dijie Liu, Marie McAnuff, Kevin<br />
G. Rice<br />
1107 11:00 <strong>AM</strong><br />
<strong>Cell</strong>ular Internalization and Distribution <strong>of</strong> DNA<br />
Complexes from <strong>Cell</strong>-Adhesive Substrates<br />
Zain Bengali, Lonnie D. Shea<br />
1108 11:15 <strong>AM</strong><br />
Ad5 Penton Base Recombinant Protein: Intracellular<br />
Trafficking &ð Implications for <strong>Gene</strong> Delivery<br />
Altan Rentsendorj, Jiansong Xie, Michelle MacVeigh, Hasmik<br />
Agadjanian, Sarah F. Hamm-Alvarez, Lali K. Medina-Kauwe<br />
1109 11:30 <strong>AM</strong><br />
Single-<strong>Cell</strong> Observations <strong>of</strong> Intracellular <strong>Gene</strong> Delivery<br />
Particles: pH Buffering and Trafficking<br />
Swaroop Mishra, Rajan P. Kulkarni, Scott E. Fraser, Mark E.<br />
Davis<br />
1110 11:45 <strong>AM</strong><br />
Selective Chemical Modification on Polyethylenimine<br />
and Its Effects on Transfection Efficiency and Cytotoxicity<br />
Xiang Gao, Dexi Liu<br />
1111 12:00 PM<br />
TAT-Streptavidin: A Novel Drug Delivery Vector for the<br />
Intracellular Uptake <strong>of</strong> Macromolecular Cargo<br />
Brian Albarran, Richard To, Patrick Stayton
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