FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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110<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
<strong>Gene</strong> Regulation: Regulated Systems and Tissue<br />
Specific Expression<br />
1050<br />
Adenoviral Clostridial Light Chain Expression in the<br />
Medial Forebrain Bundle: A Reversible Model <strong>of</strong><br />
Dopamine Depletion<br />
Mary E. Garrity-Moses, Qingshan Teng, Jun Yang, Thais<br />
Federici, Erin Gilbert, Thyagarajan Subramanian, Nicholas M.<br />
Boulis<br />
1051<br />
Prostate Cancer-Targeted Suicide <strong>Gene</strong> <strong>Therapy</strong><br />
Achieved Effective Tumor Destruction While Safeguarding<br />
Against Systemic Toxicity<br />
Mai Johnson, Makoto Sato, Burton Jeremy, Sanjiv S. Gambhir,<br />
Michael Carey, Lily Wu<br />
1052<br />
A Versatile Chimeric Enhancer Vector That Is Highly<br />
Inducible by Hypoxia and Metals<br />
Jonghoe Byun, Jae-Young Lee, Young-Sam Lee, Jeong-Min<br />
Kim, Hyung-Suk Jang, Koung Li Kim, In-Soon Shin, Jung-<br />
Sun Lee, Wonhee Suh, Eun-Seok Jeon Duk-Kyung Kim<br />
1053<br />
Novel Exogenously Regulated Stem <strong>Cell</strong>–Mediated<br />
<strong>Gene</strong> <strong>Therapy</strong> Platform for Spinal Fusion<br />
Gadi Pelled, Amir Hasharoni, Yoram Zilberman, Gadi<br />
Turgeman, Gregory A. Helm, Meir Libergall, Dan Gazit<br />
1054<br />
Bio-Distribution Studies <strong>of</strong> Lentiviral Vectors Injected<br />
Intravenously by Dynamic Bioluminescence Imaging<br />
Analyses: Development <strong>of</strong> APC-Transcriptionally<br />
Targeted Vectors for <strong>Gene</strong>tic Vaccination Purposes<br />
Takahiro Kimura, Richard C. Koya, Nori Kasahara, Renata<br />
Stripecke<br />
1055<br />
Reduced Toxicity Selection <strong>of</strong> Modified Murine Repopulating<br />
Stem <strong>Cell</strong>s Results in an Unchanged Differentiation<br />
Potential <strong>of</strong> Oligoclonal MGMT-P140K<br />
Overexpressing Murine Hematopoiesis<br />
C. Ball, M. Schmidt, C. von Kalle, H. Glimm<br />
1056<br />
Suppression and Enhancement <strong>of</strong> <strong>Gene</strong> Repair by the<br />
Modulation <strong>of</strong> ATM Function in Mammalian <strong>Cell</strong>s<br />
Julia Engstrom, Luciana Ferrara, Hetal Parekh-Olmedo, Eric B.<br />
Kmiec<br />
1057<br />
<strong>Gene</strong>rating Efficient Promoters for Cardiovascular <strong>Gene</strong><br />
<strong>Therapy</strong> Using Synthetic Promoter Libraries<br />
Stuart A. Nicklin, Anna F. Dominiczak, Andrew H. Baker<br />
1058<br />
Novel Prostate-Specific Vector Regulation System<br />
Incorporating a Probasin-Based Promoter, Tet-Regulated<br />
Transcriptional Silencer Protein, and a Positive Feedback<br />
Loop<br />
Jan Woraratanadharm, Semyon Rubinchik, Hong Yu, John<br />
(Jian-yun) Y. Dong<br />
1059<br />
Development <strong>of</strong> a Novel Regulatory System Allowing<br />
Doxycycline-Controlled Suppression <strong>of</strong> Target <strong>Gene</strong>s in<br />
Mammalian <strong>Cell</strong>s<br />
Lahouari Amar, Jacques Mallet, Roland Vogel<br />
1060<br />
An Efficient GLP-1 Expression System Using Two Step<br />
Transcription Amplification for Type 2 Diabetes <strong>Gene</strong><br />
<strong>Therapy</strong><br />
Kyung Soo Ko, Minhyung Lee, Seungjoon Oh, Eunsu Lee,<br />
Cheol-Hee Ahn, Byoung Doo Rhee<br />
1061<br />
An Ecdysone Receptor-Based <strong>Gene</strong> Switch for Precisely<br />
and Variably Regulated Expression <strong>of</strong> <strong>Gene</strong>s in Mammalian<br />
<strong>Cell</strong>s<br />
Anand K. Katakam, Chris L. Herold, Prasanna Kumar<br />
1062<br />
Potential Utility <strong>of</strong> Heat Shock Protein 70 Promoter<br />
(HSP70-P) as a Stress Responsive Promoter in <strong>Gene</strong><br />
Delivery: HSP70-P Regulated Expression <strong>of</strong> Transgenes<br />
SOD1 and GPX1<br />
Lokesh Agrawal, David S. Strayer<br />
1063<br />
Independent Modulation <strong>of</strong> Multiple <strong>Gene</strong>s Using<br />
Modified Ecdysone Receptors<br />
Jennifer L. Friz, Robert E. Hormann, Prasanna Kumar, Dean<br />
E. Cress<br />
1064<br />
Possible Involvement <strong>of</strong> Hypoxia Inducible Factor and<br />
Inflammatory Cytokines in the Development <strong>of</strong> Rat<br />
Cerebral Collateral Circulation<br />
Mitsuhiro Anan, Tatsuya Abe, Takeshi Matsuda, Ryo Inoue,<br />
Keisuke Ishii, Minoru Fujiki, Hidenori Kobayashi<br />
1065<br />
<strong>Gene</strong>ticin Targets Nonsense-Mediated mRNA Decay in<br />
Epidermolysis Bullosa<br />
Alfred Klausegger, Verena Wally, Kamil Oender, Helmut<br />
Hintner, Johann Bauer<br />
1066<br />
Optimisation <strong>of</strong> the Tet-On System for In Vivo Electro<br />
<strong>Gene</strong> Transfer to Muscle Tissue in Mice<br />
Pernille H. Moller, Jens Eriksen, Lluis M. Mir, Julie Gehl
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