FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 105<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
970<br />
p53 Expression and Serum IgE Levels in Patients with<br />
Neur<strong>of</strong>ibromatosis type 1<br />
Mauro Geller, Marcia G. Ribeiro, Alexandra P. Q. C. Araújo,<br />
Kalynka S. Higino, Rafael B. Varella, Lisa B. Oliveira, Fabio P.<br />
Nunes, Joâo G. R. Gonçalves<br />
971<br />
Human Embroyonic Stem <strong>Cell</strong>s Transplantation on<br />
Paralytic Patients<br />
Geeta Barthakur Shr<strong>of</strong>f<br />
972<br />
HSC-Based Ex Vivo <strong>Gene</strong> <strong>Therapy</strong> Prolongs Survival<br />
and Improves the Phenotype <strong>of</strong> Globoid <strong>Cell</strong> Leukodystrophy<br />
Mice<br />
Alessandra Biffi, Ilaria Visigalli, Letterio S. Politi, Angelo<br />
Quattrini, Ubaldo Del Carro, David Wenger, Claudio<br />
Bordignon, Luigi Naldini<br />
<strong>Gene</strong> <strong>Therapy</strong> for Infections and Vaccines<br />
973<br />
Targeting <strong>of</strong> CCR5 through Intrabody Mediated HIV-1<br />
Vector <strong>Gene</strong> Delivery Is Sufficient for Blocking HIV-1-<br />
Infection and Confers a T-<strong>Cell</strong> Survival and Growth<br />
Advantage<br />
Christina H. Swan, Kimberlee M. Fischer, Bernd Bühler, Mario<br />
P. Tschan, Carlos F. Barbas, III, Bruce E. Torbett<br />
974<br />
Towards <strong>Gene</strong> Knock out <strong>Therapy</strong> for AIDS/HIV:<br />
Targeted Disruption <strong>of</strong> CCR5 Using Engineered Zinc<br />
Finger Protein Nucleases (ZFNs)<br />
Yann Jouvenot, Elena Perez, Fyodor D. Urnov, Christian<br />
Beausejour, Jeremy Rock, Ya-Li Lee, Jeffrey C. Miller, Edward J.<br />
Rebar, Michael C. Holmes, Dale Ando Jim Riley, Philip D.<br />
Gregory, Carl June<br />
975<br />
Immunization with an Adenovirus Vector Expressing a P.<br />
aeruginosa OprF Epitope in the Capsid Enables Boosting<br />
<strong>of</strong> Anti-Epitope Immune Responses and Protects Against<br />
Pulmonary Infection with P. aeruginosa<br />
Stefan Worgall, JianPing Qiu, Anja Krause, Kyung-Hee Kim,<br />
Peter W. Roelvink, Joseph T. Bruder, Thomas J. Wickham, Imre<br />
Kovesdi, Ronald G. Crystal<br />
976<br />
IFNα <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Woodchuck Hepatitis with<br />
Adeno-Associated Virus: Differences in Duration <strong>of</strong><br />
<strong>Gene</strong> Expression and Antiv<br />
iral Activity Using Intraportal or Intramuscular Routes<br />
Berraondo Pedro, Ochoa Laura, Crettaz Julien, Rotellar<br />
Fernando, Vales Africa, Martinez-Anso Eduardo, Zaratiegui<br />
Mikel, Ruiz Juan, Prieto Jesus, Gonzalez-Aseguinolaza Gloria<br />
977<br />
CD4 + T <strong>Cell</strong> Independent DNA Vaccination Against<br />
Pneumocystis Carinii in Mice<br />
Mingquan Zheng, Myle Robicchaux, Christoph Kliment, Judd<br />
E. Shellito, Jay K. Kolls<br />
978<br />
Production <strong>of</strong> SARS Coronavirus-Like Particles That<br />
Bind Host <strong>Cell</strong>s and Serve as Vaccine Antigen<br />
Yi-Chun Yeh, En-Hau Lin, Chang-Jen Huang, Ning-Sun<br />
Yang, Pei-Wen Hsiao<br />
979<br />
Antigen-Transduced T <strong>Cell</strong> Blasts Specifically Delete<br />
Antigen-Specific Cytotoxic T <strong>Cell</strong>s and Induce a<br />
CD4+CD25+ Regulatory T <strong>Cell</strong> Response<br />
Aaron E. Foster, Takayuki Okamura, Cliona M. Rooney<br />
980<br />
Specific Immune Response Against the Plasmodium<br />
falciparum CS Protein Mediated by Baculovirus Vectors<br />
Robert Strauss, Andreas Hüser, Nelson Di Paolo, Andre Lieber,<br />
Christian H<strong>of</strong>mann<br />
981<br />
Modulation <strong>of</strong> Human Dendritic <strong>Cell</strong> Function Following<br />
Viral Vectors: Implications for <strong>Gene</strong> <strong>Therapy</strong> in<br />
Vaccination<br />
Peng H. Tan, Giovanna Lombardi, Andrew J. T. George<br />
982<br />
Lentiviral Vector Mediated <strong>Gene</strong>tic Modification <strong>of</strong><br />
Dendritic <strong>Cell</strong>s as a Vaccine Against Hepatitis C<br />
Richard C. Koya, Yi Zheng, Emmanuelle Faure, Guann-yi Yu,<br />
Takahiro Kimura, Nori Kasahara, Renata Stripecke<br />
983<br />
Inhibition <strong>of</strong> Hepatitis C Virus Replication by In Vitro<br />
Selected Specific RNA Aptamers<br />
Jung-Hye Kim, Nam Yeon Kim, Seong-Wook Lee<br />
984<br />
Directed Molecular Evolution <strong>Gene</strong>rates Novel HIV-1<br />
Envelope Variants That Can Elicit Broadly Neutralizing<br />
Antibody Responses in Rabbits<br />
Li Xu, Xiaohan Du, Wenge Zhang, Susan Tang, NayWei<br />
Soong, Michael Zwick, Dennis Burton, Robert Whalen<br />
985<br />
Targeting CCR3 To Protect from Human Immunodeficiency<br />
Virus (HIV-1)<br />
Lokesh Agrawal, David S. Strayer<br />
986<br />
In Vivo Production <strong>of</strong> Anti-HIV-1 Neutralizing Antibody<br />
from Rhesus Macaque Muscle Using a Recombinant<br />
Adeno-Associated Virus Vector<br />
K. Reed Clark, Jianchao Zhang, David C. Montefiori, Philip<br />
R. Johnson
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