FINAL PROGR AM - American Society of Gene & Cell Therapy

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AMERICAN SOCIETY OF GENE THERAPY • Final Program 101 ABSTRACTS SATURDAY, JUNE 4 907 Gene Therapy for Genetic Lipoprotein Lipase (LPL) Deficiency; an Update Jaap Rip, Melchior C. Nierman, Jeroen A. Sierts, Colin J. Ross, Michael R. Hayden, Albertine de Jong, Paul Dijkhuizen Wim Hermens, Jaap Twisk, John J. Kastelein, Jan Albert Kuivenhoven, Janneke M. Meulenberg 908 Evaluation of the Sleeping Beauty Transposon System in OTC Deficient Spf-Ash Mice: A Non-Viral Approach to a Cell Autonomous Metabolic Disease Andy Wilber, Joel Frandsen, Hiroki Morizono, Mendel Tuchman, R. Scott McIvor 909 Sustained Correction of Glycogen Storage Disease Type II by rAAV1 Vector-Mediated Gene Therapy Kerry O. Cresawn, Cathryn S. Mah, Thomas J. Fraites, Jr., Melissa A. Lewis, Irene Zolotukhin, Barry J. Byrne 910 AAV8-Mediated Expression of Glucocerebrosidase Ameliorates the Storage Pathology in the D409V/null Gaucher Mouse Kerry McEachern, John Marshall, Jennifer B. Nietupski, Karen M. Brennan, Christine M. Barbon, Wei-Lien Chuang, William Kennedy, Gregory A. Grabowski, Seng H. Cheng 911 Comparison of rAAV Serotype, Promoter, and Treatment Age for the Correction of Glycogen Storage Disease Type II Kerry O. Cresawn, Cathryn S. Mah, Irene Zolotukhin, Melissa A. Lewis, Barry J. Byrne 912 Long-Term Efficacy of AAV Vector-Mediated Gene Therapy in the Mouse Model for Glycogen Storage Disease Type la (GSD-Ia) Dwight D. Koeberl, Baodong Sun, Tirupapuliyur Damodaran, Talmage Brown, Andrew Bird, Ayn Schneider, David S. Millington, Y.-T. Chen 913 Development and Characterization of CF Airway Epithelial Cell Lines Complemented with Wild-Type and ∆F508 CFTR cDNA Rosalie Maurisse, Beate Illek, Judy Cheung, Tusyoshi Shuto, Hirofumi Kai, Horst Fischer, Dieter C. Gruenert 914 A Dichotomous Role for Interleukin-10 in the Pathogenesis of Type 1 Diabetes Greg G. Simon, Fletcher Schwartz, Clive Wasserfall, Mark A. Atkinson 915 Adenovirus Transduction May Be Involved in the Transdifferentiation of the Liver to the Pancreas Alfred Y. Wang, Anja Ehrhardt, Hui Xu, Mark A. Kay Cardiovascular: Myocardial Gene Therapy 916 Sustained Whole-Body Functional Rescue by Systemic Delivery of AAV8 Vectors in Heart Failure and Muscular Dystrophy Hamsters Tong Zhu, Liqiao Zhou, Satsuki Mori, Zhong Wang, Charles Mctiernan, Chunping Qiao, Chunlian Chen, Daowen Wang, Juan Li, Xiao Xiao 917 Engineered Cell Therapy for Sustained Local Myocardial Delivery of Non-Secreted Proteins Jing Bian, Niladri Mal, Matt Kiedrowski, Farhad Forudi, Marc S. Penn 918 Nanoparticle Mediated Gene Delivery to Magnetized Implants Benjamin B. Yellen, Michael Chorny, Ilia Fishbein, Darryl N. Williams, Candice M. Klingerman, Ivan S. Alferiev, Origene Nyanguile, Gary Friedman, Robert J. Levy 919 Magnetic Nanoparticle Mediated Gene and Cell Delivery Darryl N. Williams, Michael Chorny, Benjamin B. Yellen, Ilia Fishbein, Stanley J. Stachelek, Origene Nyanguile, Gary Friedman 920 Muscle Stem Cells Provide Superior Infarct Repair When Compared with Myoblasts Hideki Oshima, Thomas R. Payne, Kenneth L. Urish, Tetsuro Sakai, Yiqun Ling, Burhan Gharaibeh, Kimimasa Tobita, Bradley B. Keller, James H. Cummins, Johnny Huard (Note: Abstract 921 has been moved from Poster Session III to Poster Session II and will follow Abstract 639.) 921 Steps toward Cardiomyopathy Gene Therapy: In Vivo Expression of Human VLCAD J. Lawrence Merritt II, Jerry Vockley, Dietrich Matern, Miao He, David B. Schowalter 922 Paracrine Alterations of Endothelial Cells Adhesion Complexes; Implications for Stem Cell Homing Ion S. Jovin, Jinette D. Abbott, Thomas Manes, Zhenrong Hao, Lei Li, Reed P. Hickey, Yan Huang, Dingang Liu, Martin S. Kluger, Frank J. Giordano
102 8th Annual Meeting • June 1 - 5, 2005 • St. Louis ABSTRACTS SATURDAY, JUNE 4 923 Muscle Stem Cells Genetically Modified to Express a VEGF Antagonist Display an Impaired Ability for Cardiac Repair Thomas R. Payne, Hideki Oshima, Masaho Okada, Nobuo Momoi, Kimimasa Tobita, Bradley B. Keller, Hairong Peng, Johnny Huard 924 High Transgene Expression Efficiency Does Not Directly Reflect High Plasmid DNA Uptake Efficiency: Comparison between Skeletal and Cardiac Muscle N. Sarkar, T. Gustavsson, A. Freyschuss, B. Norman, A. Wiik, P. Blomberg, V. Drvota, C. Sylven 925 pVGI.1 (VEGF2) Biodistribution in Swine Following Injection into Anterior Wall of the Left Ventricle Using the Stiletto Endocardial Direct Injection Catheter System Qing Wang, Yawen L. Chiang 926 Recombinant AAV Vectors Pseudotyped with Serotype-1 Capsid Mediates Early Onset of Gene Expression in Mouse Hearts Hua Su, Yu Huang, Alicia Barcena, Janice Arakawa-Hoyt, Jianqin Ye, William Grossman, Yuet W. Kan 927 Human Mesenchymal and Hematopoietic Stem Cell Contribution to Cardiac Tissue Regeneration after Injury Ivana Rosova, Jan A. Nolta 928 Nonclinical Safety Study of Direct Myocardial Injection of pVGI.1 (VEGF2) Using the Stiletto Endocardial Direct Injection Catheter System in a Swine Model Qing Wang, Robert Rapoza, Wendy Naimark, Hsing-Yi Jan, Yawen L. Chiang 929 CD9 Gene Therapy Inhibits Cardiac Hypertrophy and Tachycardia, and Attenuates the Remodeling after Myocardial Infarction in Mice Hiroaki Ushikoshi, Tomoyuki Takahashi, Genzou Takemura, Yuwen Li, Masayasu Esaki, Ngin Cin Khai, Takao Kawai, Shinya Minatoguchi, Takako Fujiwara, Hisayoshi Fujiwara Ken-ichiro Kosai 930 Magnetically Responsive Polylactide-Based Nanoparticles Potently Enhance Non-Viral Gene Transfer Boris Polyak, Michael Chorny, Ivan Alferiev, Robert J. Levy 931 Refractory Period Prolongation by Fibroblasts Overexpressing the Mutant Kv1.3 H401W Channel in Computer Simulation and Pig Hearts Ariel Shabtay, Tal Bresler, Lior Yankelson, Lior Gepstein, Shimon Marom, Yair Feld 932 Gene Therapy for Diabetes Mellitus in Rats by Intramuscular Injection of Lentivirus Containing Insulin Gene Taekeun Oh, Mija Lee, Seungtaik Kim 933 Closed-Chest Cell Injections into Mouse Myocardium Guided by High-Resolution Echocardiography Matthew L. Springer, Richard E. Sievers, Mohan N. Viswanathan, Michael S. Yee, Elyse Foster, William Grossman, Yerem Yeghiazarians 934 Initial Results of the Treatment of a Cardiomyopathy in Myopathic Hamsters by IGF-1 Based on Plasmid DNA Gene Transfer Armelle Serose, André Salmon, Marc Y. Fiszman, Yves Y. Fromes 935 Restoration of Impaired Myocardial Contractility by Overexpressing Sarcoplasmic Reticulum Calcium ATPase through Recombinant Adeno-Associated Xiaochun Lu, Haipeng Hui, Xiaoying Li, Xiaobing Wu 936 Vascular Tropism of Lentiviral Vectors Using Bunyaviral- Pseudotyped Lentiviral Vectors James R. Gilbert, Zhong Qian, Jody R. Arsenault, Jennifer E. Aquirre, Julio A. Lemos, Frank Park 937 Generation of Anti-LOX-1 Cytotoxic T Lymphocytes by AAV Manipulation of Dendritic Cells towards Preventing Atherosclerosis Jin Xie, Jay L. Mehta, Jawei Chen, Yong Liu, Paul L. Hermonat 938 Intramuscular Administration of AAV Vector Expressing Interleukin-10 in Dahl Salt-Sensitive Rats Prevents the Development of Hypertensive Heart Disease Mutsuko Sarukawa, Takashi Okada, Toru Yoshioka, Tatsuya Nomoto, Takayuki Ito, Yoshikazu Maeda, Masahisa Shimpo, Takashi Matsushita, Hiroaki Mizukami, Kuniko Shimazaki Akihiro Kume, Keiji Yamamoto, Uichi Ikeda, Kazuyuki Shimada, Keiya Ozawa
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156 NOTES 8th Annual Meeting • Ju
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FINAL PROGR AM - American Society of Gene & Cell Therapy

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