FINAL PROGR AM - American Society of Gene & Cell Therapy

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AMERICAN SOCIETY OF GENE THERAPY • Final Program 99 ABSTRACTS SATURDAY, JUNE 4 873 Adenovirus Polypeptide IIIa as a Novel Locale for Incorporation of Heterologous Peptides Joel N. Glasgow, Elena Kashentseva, Igor P. Dmitriev, David T. Curiel 874 Long-Term Transgene Expression In Vivo from a Helper Dependent Adenovirus—Epstein-Barr Virus Hybrid Vector Sean D. Gallaher, Jose S. Gil, Oliver Dorigo, Arnold J. Berk 875 Adenoviral Vector Targeting – New Targets for Old Capsids Douglas E. Brough, Hinrich Staecker, Masaki Akiyama, Chi Hsu, Selva R. Murugesan, David A. Einfeld, Jason G. Gall, Lisa L. Wei, Melissa Hamilton, Duncan McVey C. Richter King 876 Development of a Novel Adenovirus-Alphavirus Hybrid Vector Providing High Efficacy and Safety in the Treatment of Liver Cancer Min Guan, Cristian Smerdou, Juan R. Rodriguez-Madoz, M. Gabriela Kramer, Stefan Kochanek, Jesus Prieto, Cheng Qian 877 Long-Term Transgene Expression with a Second Generation Hybrid AdenoRetroviral Vector Changyu Zheng, Weitan Zhang, Joseph M. Vitolo, Bruce J. Baum 878 Toward ‘Pseudotyping’ Adenovirus Vectors: Efficient Generation of pIX-Expressing Helper Cell Lines Rob C. Hoeben, Taco G. Uil, Jeroen De Vrij, Leif Lindholm, Jort Vellinga 879 Transduction Enhancement by the Adenovirus/Polymer Complexes Derivatized with Protein Transduction Domain Peptides Ilia Fishbein, Ivan S. Alferiev, Richard Gaster, Michael Chorny, Origene Nyanguile, Robert J. Levy 880 AAV-Rep 78 Mediated Rescue of a 27kb Transgene Cassette from a Helper-Dependent Ad Vector Genome Hongjie Wang, Dmitry Shayakhmetov, Andre Lieber 881 Development of Novel E1-Complementary Cells for Adenoviral Production Free of Replication Competent Adenovirus Deborah Farson, Lucy Tao, Derek Ko, Thomas Harding, Dominic Brignetti, De-Chao Yu, Yuanhao Li 882 Development of a Transposon-Based Approach to Identification of Novel Transgene Insertion Sites within Replicating Viral Genomes Peter Kretschmer, Fang Jin, Cecile Chartier, Paul Harden, Terry Hermiston 883 Gold Nanoparticles as an Amplifying Payload Strategy for Adenoviral Cancer Gene Therapy Maaike Everts, Jennifer L. Leddon, Robbert J. Kok, Meredith A. Preuss, C. Leigh Millican, David E. Nikles, Duane T. Johnson, David T. Curiel 884 Integration of a Helper-Dependent Adenovirus Mediated by the Phage FðC31 Integrase Rénald Gilbert, Laurie Desfossé, Émilie Mairey, Benoît Raymond, Michele P. Calos, Jacques P. Tremblay, Bernard Massie 885 Calcium Phosphate Coprecipitation Enhances Adenoviral Vector-Based Gene Transfer to Murine Bone Marrow Derived Dendritic Cells Michael P. Seiler, Vincenzo Cerullo, Philip Ng, Donna Palmer, Brendan Lee 886 An Adenovirus Vector with a Chimeric Fiber Derived from Ovine Adenovirus for Novel Tropism Discovery Masaharu Nakayama, Joel N. Glasgow, Gerald W. Both, Massimo Palmarini, Yuko Tsuruta, Kenzaburo Tani, Joanne T. Douglas, David T. Curiel 887 Reducing the Incidence of Replication Competent Adenovector by Engineering the Vector Genome G. Campbell Kaynor, Jennifer L. Brown, Rhonda Brown, Xinzhong Wang 888 Optimization of Adenovirus Serotype 35 Vectors for Efficient Transduction in Human Hematopoietic Progenitors; Comparison of Promoter Activities Fuminori Sakurai, Hiroyuki Mizuguchi, Kenji Kawabata, Teruhide Yamaguchi, Takao Hayakawa 889 Lanthanum Enhances Adenovirus-Mediated Gene Transfer Oliver B. Betz, Glyn D. Palmer, Volker M. Betz, Keith Crawford, Christopher Niyibizi, Mark S. Vrahas, Christopher H. Evans
100 8th Annual Meeting • June 1 - 5, 2005 • St. Louis ABSTRACTS SATURDAY, JUNE 4 890 Development of a Single Vector System for Gene Delivery Via Hybrid Helper Dependent Adenovirus - Epstein-Barr Virus Vector for Long Term Persistance Jose S. Gil, Sean D. Gallaher, Oliver Dorigo, Arnold J. Berk 891 A Flexible System for Ad35-Based Vector Generation Wentao Gao, Angela Montecalvo, Huijie Sun, Paul D. Robbins, Andrea Gambotto 892 GeneJammer® Enhances Cellular Transduction with Recombinant Adenovirus Christine M. Dilling, Pablo Bosh, Alan R. Davis, Jessica A. Shafer, Steven Stice, Malavosklish Bikram, Jennifer L. West, Elizabeth A. Olmsted-Davis 893 Using QPCR and Automation to Assign Infectious Potencies to Adenovirus Based Vaccines and Vectors for Gene Therapy Alan C. Puddy, Jenny Xu, Amy M. Bowman, Yuhua Zhang, Charles Y. Tan, Timothy L. Schofield, Peter A. DePhillips, John A. Lewis, Jayanthi J. Wolf Inborn Errors of Metabolism: Liver and Pancreatic Diseases 894 A Novel Mechanism between Type II Diabetes Mellitus and Procalcitonin Gene Expression Mehment Ali Soylemez, Oktay Seyment, Gunnur Yigit 895 Ex Vivo Gene Therapy of Metabolic Liver Disorders Using Uncultured and Lentivirally Transduced Hepatocytes Tuan Huy Nguyen, Jacques Birraux, Barbara Wildhaber, Catherine Fux, Francois Trivin, Anne Myara, Claude Lecoultre, Didier Trono 896 Complete and Permanent Correction of Hyperbilirubinemia in Newborn Gunn Rats by Lentiviral-Mediated Gene Transfer Tuan huy Nguyen, Marta Bellodi-Privato, Dominique Aubert, Anne Myara, Didier Trono, Nicolas Ferry 897 Recombinant AAV2/8 Vector-Mediated Gene Therapy Corrects Hyperphenylalaninemia in Murine PKU Cary O. Harding, Melanie B. Gillingham, Kelly Hamman, Andrew Bird, Dwight Koeberl 898 Liver-Directed, AAV- and Lentivirus-Mediated Gene Therapy in the Phenylketonuria Mouse Model Pah-enu2 Zhaobing Ding, Panco Georgiev, Beat Thony 899 Glucose-Stimulated Insulin Secretion from an Engineered Human Liver Cell Line Is Regulated by ATP- Sensitive Potassium Channels and the L-Type Calcium Channel Ann M. Simpson, Edwin Ch’ng, Guo J. Liu, Chang Tao, Donald K. Martin, Mark Lutherborrow, Bernard E. Tuch 900 Overcoming Gender-Specific Barrier of AAV-Mediated Gene Therapy by Neonatal Intervention Akihiro Kume, Tsuyoshi Ogura, Hiroaki Mizukami, Shigeo Kure, Takashi Okada, Masashi Urabe, Takashi Matsushita, Keiya Ozawa 901 Recovery from Type 1 Diabetes by Insulin and Glucokinase Expression in Skeletal Muscle Joel Montane, Alex Mas, Xavier M. Anguela, Anne M. Douar, Pedro J. Otaegui, Fatima Bosch 902 In Toto Gene Correction by Meganuclease-Induced Homologous Recombination in Mouse Liver Agnes Gouble, Valerie Guyot, Jean-Pierre Cabaniols, Sophie Leduc, Sandra Rolland, Frederic Paques, Philippe Duchateau 903 Ornithine Transacarbamylase Deficiency Correction with Low Dose of Helper-Dependent Adenoviral Vector Nicola Brunetti-Pierri, Christian Clarke, Viraj Mane, Donna Palmer, Philip Ng, William O’Brien, Brendan Lee 904 High Efficiency Hepatic Transduction and Long-Term Transgene Expression by Delivering Helper-Dependent Adenoviral Vectors into the Surgically Isolated Liver of Nonhuman Primates Nicola Brunetti-Pierri, Thomas Ng, David Iannitti, William Cioffi, Donna Palmer, Arthur Beaudet, Milton Finegold, Dee Carey, Philip Ng 905 Hydrodynamic Injection of Helper-Dependent Adenoviral Vectors Increases Liver Transduction Efficiency and Decreases Acute Inflammatory Response Nicola Brunetti-Pierri, Viraj Mane, Donna Palmer, Arthur Beaudet, Milton Finegold, Philip Ng 906 High Efficiency Hepatic Transduction with Minimal Toxicity Following “Hydrodynamic” Injection of HDAd into Nonhuman Primates Nicola Brunetti-Pierri, Charles Mullins, Donna Palmer, Milton Finegold, Arthur Beaudet, Karen Rice, Dee Carey, Philip Ng
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156 NOTES 8th Annual Meeting • Ju
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FINAL PROGR AM - American Society of Gene & Cell Therapy

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