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Continued from page 11 – Study Suggests New MalariaDrugcombination of several malaria control measures,including treatment with ACTs, provision of ITNs(with education about their use), and potential use ofindoor residual spraying as has been the case in SouthAfrica.This, they argued, will likely decrease the malariaburden and reduce drug pressure due to repeated use ofACTs.Monitoring of the impact of these combined controlmeasures will be critical to assess success in malariacontrol in Uganda, they further observed.The study results could have important policyimplications, according to the researchers, whoobserved children aged 6 months to 10 years withuncomplicated falciparum malaria in the study,‘Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Malaria: A RandomizedTrial.’☻☻☻☻☻☻Shs3.7b Malaria, ARV DrugsRot in NMSAgness NandutuJuly 12, 2007Daily MonitorAs thousands of Ugandans die everyday of HIV/AIDSand malaria, drugs worth about Shs4 billion are rottingin the National Medical Stores Entebbe.While on their fact finding tour of NMS in Entebbeyesterday, MPs on the Social Services Committee ledby James Kubeketerya (Bunya East) were shocked tofind eight containers of 2-feet, full of expired drugs yetUgandans are perishing in hospitals with treatment.The NMS General Manager Apollo Newton Mwesigyetold MPs that due to over stocking of drugs by thirdparty programmes at NMS, ARV drugs valued atShs900 million and other drugs work Shs1.2 billionhave already expired. Those that are bout to expire arevalued at Shs1.65 billion.Third parties are programmes like Global Funds thatstore drugs at NMS.Mr Mwesigye said, “Due to unique nature of NMSoperations, expiry of drugs has remained a bigchallenge. We can only minimize these losses if NMSis given power to perform its statutory mandate ofprocurement, storage and distribution of drugs. We can-not do away with the expire drugs but if procurement isharmonized, we can reduce,” he told MPs.Former NMS General Manager Robert Rutagi was last yearsuspended for the mismanagement that led to the expiry ofARV packs worth Shs936 million.Thousands of Ugandans die of malaria and HIV/AIDSannually due to inadequate drugs in hospitals countrywide.He told MPs that big volumes of expire drugs and thosethat are about to expire belong to third party programmesbut few of the drugs belong to NMS.Out of the 13,000 square metre-storage space, only 2000store NMS drugs.Mr. Mwesigye told MPs that third party programmesprocure big volumes of drugs, which are sometimes alreadyprocured by NMS.“NMS is not involved in the planning or procurement of theitems and we are expected to accept all consignments atvery short notice. This has led to a distortion in NMS henceexpiry,” he said.He said many of the programmes procure short-lived drugsand leave them for a long time at NMS, which in manycases expire. Mr. Kubeketerya demanded for the list ofprogrammes that bring in the drugs that expire at NMS.“If you don’t expose them, it’s your name that gets spoiled.It’s proper to avail to us the names of these programmes sothat people get to know their negligence,” he said.Some of the programmes that were named to have leftdrugs for a long time at NMS to expire are Global Fund,Aids Control Programme, Clinton Foundation, MalariaControl Programme among others.Mr. Mwesigye told MPs that there is an increased numberand volume of redundant stock at NMS.He said high on the redundant stock list are condoms,homapaks for malaria, ARV oral dosage forms and syrups,Uganda Aids Commission lab supplies and other Globalfund stock among others.“This translates into high inventory holding costs and theexpiry risk that in turn leads to financial loss. This isbecause NMS is not involved in the planning andprocurement of the items,” he said.He said big volumes of the drugs that expire have a shortlife span and are brought in without proper planning.-12 - Traditional African Clinic July/August 2007He said some of the drugs are procured in preparation foroutbreaks like bad flu but expire if the outbreaks don’toccur. Said Mr Mwesigye “If there is harmonizing ofprocurement with third party programmes, we can doproper planning and schedule the distribution in a wellContinued on page 13
Continued from page 12 –Shs3.7b Malaria, ARV Drugs Rotin NMScoordinated manner to reduce expired drugs,” he said.Rukiga MP Samuel Byanangwa said, “These donorsshould be told how it works. How can they bring in drugsand them fail to distribute them? Uganda is not adumping ground.”☻☻☻☻☻☻Quinine Crippling ChildrenRichard Otim, KumiMay 7, 2007Daily MonitorKumi Hospital Medical Superintendent John Opolot hasasked the government to prohibit the use of quinineinjections as malaria treatment, saying the drug iscrippling children.He said whereas no case of polio related disabilities hadbeen reported in Kumi district for the past five years,quinine has been the cause of the increasing cases ofdisability among infants.He was speaking to Daily Monitor last week in KumiDistrict.“Quinine is very toxic and most cases of disability wereported are due to post injection paralysis.” Dr. Opolotsaid.He said some infants develop “glutial fibrosis”, orhardening of the child buttocks, after administering thedrug.“Parents should insist on oral or intravenousadministration of the drug and by qualified healthpersonnel,” Dr Opolot said. He said the cases, whichrange from physical to mental disabilities, have beeninflicted on children by mal-administration of quinineinjection conducted especially by quack health assistants.He said this result into post injection paralysis.Quinine may also cause paralysis, hearing problems, andblindness in adults. Medical personnel advise that one onquinine treatment should take a lot of fluids to avoid suchcomplications.☻☻☻☻☻☻Fake Quinine on MarketHussein Bogere & Jane NafulaMay 10, 2007Daily MonitorThe public has been warned against using counterfeit Quinetablets in the treatment of Malaria. The warning came fromthe National Drug Authority, which together with theMinistry of Health have launched an investigation into thesource of the counterfeit Malaria tablets.NDA lifted the lid on the counterfeits yesterday in a publicstatement.“It has come to our attention that counterfeit Quine®(Quine Sulphate) BP 300mg tablets have found their wayinto the Ugandan market,” the statement reads in part.NDA however, warns that any one found selling the tabletswill be prosecuted.“We are investigating, if there is anything wrong, the lawwill take its course,” Sam Okware, the Commissioner forCommunity Health (in the Ministry of Health) told DailyMonitor yesterday.NDA says the particulars appearing on the tin of thecounterfeit Quine tablets are Batch No. 0908 with amanufacturing date of 05/2005 and expiry 04/2009.“Contrary to what is purported on the label, the productwith the above particulars has not been manufactured in thefacilities of Kampala Pharmaceutical Industries (1996) Ltdin Uganda. They are the sole license holders andmanufacturers of Quine® tablets which are registered inUganda Reg. No 0780/06/97,” NDA warns.NDA further warns that anybody found selling thecounterfeit tablets will be prosecuted because their sale,purchase and use has been prohibited immediately.The available stock must be quarantined as well, NDA said.DangerousDr. Okware said the sale of counterfeit drugs is a verydangerous practice. “Those drugs have adverse effects onthe users because they give a false sense of security, theydon’t cure and they easily cause side effects.” He saidnormal drugs must not have side effects.Lately, there have been reports of patients experiencingside effects as a result of using Quinine. On Monday, KumiHospital Medical Superintendent John Opolot asked thegovernment to prohibit the use of Quinine injectionsbecause they were crippling children. He said maladministrationof Quinine injections has inflicted a rangeContinued on page 14-13 - Traditional African Clinic July/August 2007
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