download dit document - ICU

2001 SCCM/ESICM/ACCP/ATS/SISInternational Sepsis Definitions Conference• Fever > 38°C• Hypothermia 90 bpm• Tachypnoe > 30 bpm• Significant edema/positive fluid balance> 20ml/kg over 24 hrs• Hyperglycemia in absence of DM• Leukocytosis > 12,000 µl• Leukopenia < 4,000 µl• Normal WBC with > 10% immature• CRP > 2 SD above normal value• Procalcitonine > 2 SD above nl value• Cardiac index > 3.5• Arterial hypoxemia P/F < 300• Acute oliguria < 0.5ml/kg for > 2 hrs• Creatinine increase > 0.5 mg/dl• Coagulation abnormalitiesaPTT > 60 sec, INR > 1.5• Thrombocytopenia < 100,000 µl• Hyperbilirubinemia > 4 mg/dl• Hyperlactatemia > 24 mg/dl• Ileus (absent bowel sounds)• Decreased capillary refill or mottling• Altered mental status• Arterial hypotension mean < 70 mmHg• Mixed venous oxygen sat < 70%24