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ACCP/SCCM Consensus Definitions• Infection– Inflammatory response tomicroorganisms, or– Invasion of normally steriletissues• Systemic InflammatoryResponse Syndrome (SIRS)– Systemic response to a varietyof processes• Sepsis– Infection plus– ≥2 SIRS criteria• Severe Sepsis– Sepsis– Organ dysfunction• Septic shock– Sepsis– Hypotension despite fluidresuscitation• Multiple Organ DysfunctionSyndrome (MODS)– Altered organ function in anacutely ill patient– Homeostasis cannot bemaintained without interventionBone RC et al. Chest. 1992;101:1644-55.
Microbiological eventInfectionSite of infectionCausativemicroorganism
- Page 5 and 6: Neisseria Meningitidis5
- Page 7 and 8: Epidemiologie7
- Page 10: Severe Sepsis:A Growing Healthcare
- Page 15 and 16: BurnsSepsisPancreatitisInfectionSIR
- Page 17 and 18: Identifying Acute Organ Dysfunction
- Page 19 and 20: Een aantalproblemen …19
- Page 21 and 22: Definitie woord “bal” =een bolv
- Page 23 and 24: Host responseInfectionSIRS- fever o
- Page 25 and 26: 2001 SCCM/ESICM/ACCP/ATS/SISInterna
- Page 27 and 28: 2001 SCCM/ESICM/ACCP/ATS/SISInterna
- Page 30: 1) Definitie van SIRS ….. en duso
- Page 33 and 34: Sepsis classificationConsensus Meet
- Page 35 and 36: Severe Sepsis:The Final Common Path
- Page 37 and 38: BehandelingBehandeling van infectie
- Page 39: Human Protein C300CHOCHO320EGFDomai
Microbiological eventInfectionSite of infectionCausativemicroorganism
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