11.07.2015 Views

Treatment of invasive candidiasis in non-haematological patients

Treatment of invasive candidiasis in non-haematological patients

Treatment of invasive candidiasis in non-haematological patients

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Time to start antifungal therapy& hospital mortalityMorrell M, et al. AAC 2005157 <strong>patients</strong> – 2001-2004Independent determ<strong>in</strong>ants <strong>of</strong> mortality:‣ APACHE II score (one-po<strong>in</strong>t <strong>in</strong>crements) (p 12 hoursafter the first positive blood culture (AOR, 2.09; p= 0.018)4035Crude mortality rate is high,the attributable mortality ratevaries between 5-71%!Falagas EJCMID 2006Hospital Mortality (%)Garey KW et al, CID 2006230 <strong>patients</strong>Independent determ<strong>in</strong>ants <strong>of</strong> mortality:‣ APACHE II score (∆1-pt.; p

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