Guidelines for ATC classification and DDD assignment - WHOCC

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combination will, together with the relative effect of the active
components, decide the classification. In the treatment of pain caused
by spasms, the spasmolytic component must be judged as more
important than the analgesic component. Accordingly,
analgesic/antispasmodic combinations should be classified in A03 if the
main effect of the preparation is the antispasmodic action.
Combined preparations are classified in:
A03C - Antispasmodics in combination with psycholeptics
A03D - Antispasmodics in combination with analgesics
A03E - Antispasmodics and anticholinergics in combination with other
drugs
Antispasmodics, which are used specifically in the urogenital tractus, are
classified in G04BD - Urinary antispasmodics.
The DDD is equal for different routes of administration (oral,
parenteral or rectal) of the same compound and is based on the oral
dose.
A03A DRUGS FOR FUNCTIONAL BOWEL DISORDERS
Semisynthetic derivatives such as butylscopolamine, are classified in
A03B - Belladonna and derivatives, plain.
Lubiprostone is classified in A06AX - Other laxatives.
Peripheral opioid receptor antagonists are classified in A06AH.
A03AA Synthetic anticholinergics, esters with tertiary amino group
A03AB Synthetic anticholinergics, quaternary ammonium compounds
Plain preparations containing glycopyrronium are classified in this
group. Preparations containing glycopyrronium in combination with
neostigmine are classified in N07AA51. Trospium see G04BD and
A03DA.
A03AC Synthetic antispasmodics, amides with tertiary amines