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Guidelines for ATC classification and DDD assignment - WHOCC

Guidelines for ATC classification and DDD assignment - WHOCC

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J01 ANTIBACTERIALS FOR SYSTEMIC USE<br />

This group comprises antibacterials <strong>for</strong> systemic use, except antimycobacterials,<br />

which are classified in J04. The antibacterials are<br />

classified according to their mode of action <strong>and</strong> chemistry.<br />

Combinations of two or more systemic antibacterials from different third<br />

levels are classified in J01R, except combinations of sulfonamides <strong>and</strong><br />

trimethoprim, which are classified at a separate 4th level, J01EE.<br />

Combinations of antibacterials with other drugs, including local<br />

anesthetics or vitamins, are classified at separate 5th levels in the<br />

respective antibacterial group by using the 50-series. Common cold<br />

preparations containing minimal amounts of antibacterials are classified<br />

in R05X.<br />

Inhaled antiinfectives are classified here based on the fact that<br />

preparations <strong>for</strong> inhalation can not be separated from preparations <strong>for</strong><br />

injection.<br />

J01A TETRACYCLINES<br />

J01AA Tetracyclines<br />

This group comprises tetracycline antibacterials inhibiting the bacterial<br />

protein synthesis through binding to the 30-S part of ribosomes.<br />

The tetracyclines have different <strong>DDD</strong>s due to kinetic differences.<br />

The use of tetracyclines in long-term, low dose treatment of acne is<br />

not taken into account in the <strong>assignment</strong> of <strong>DDD</strong>s.<br />

J01B AMPHENICOLS<br />

J01BA Amphenicols<br />

This group comprises amphenicol antibacterials inhibiting the bacterial<br />

protein synthesis.<br />

Thiamphenicol acetylcysteinate glycinate <strong>for</strong> inhalation is classified in<br />

J01BA52.<br />

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