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Guidelines for ATC classification and DDD assignment - WHOCC

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J ANTIINFECTIVES FOR SYSTEMIC USE<br />

166<br />

Antiinfectives are also classified in the following groups:<br />

A01AB Antiinfectives <strong>and</strong> antiseptics <strong>for</strong> local oral treatment<br />

A02BD Combinations <strong>for</strong> eradication of Helicobacter pylori<br />

A07A Intestinal antiinfectives<br />

D01 Antifungals <strong>for</strong> dermatological use<br />

D06 Antibiotics <strong>and</strong> chemotherapeutics <strong>for</strong> dermatological use<br />

D07C Corticosteroids, combinations with antibiotics<br />

D09AA Ointment dressings with antiinfectives<br />

D10AF Antiinfectives <strong>for</strong> treatment of acne<br />

G01 Gynecological antiinfectives <strong>and</strong> antiseptics<br />

P Antiparasitic products, insecticides <strong>and</strong> repellents<br />

R02AB Antibiotics<br />

R05X<br />

S01/<br />

S02/<br />

Other cold combination preparations<br />

S03 Eye <strong>and</strong> ear preparations with antiinfectives<br />

Even systemically administered antibacterials <strong>and</strong> antimycotics may be<br />

classified in other groups if their target is exclusively local, e.g. the<br />

skin - D01 - Antifungals <strong>for</strong> dermatological use<br />

Inhaled antiinfectives are classified in J.<br />

The <strong>DDD</strong>s <strong>for</strong> the antiinfectives are as a main rule based on the use<br />

in infections of moderate severity. However, some antiinfectives<br />

are only used in severe infections <strong>and</strong> their <strong>DDD</strong>s are assigned<br />

accordingly. The <strong>DDD</strong>s assigned are based on daily treatment.<br />

The duration of the treatment periods is not taken into<br />

consideration. For antiinfectives given in a high initially starting<br />

dose followed by a lower daily "maintenance" dose, the <strong>DDD</strong>s are<br />

based on the "maintenance" dose if the total duration of the treatment<br />

course is more than one week. If, however, the treatment<br />

course is 7 days or less, the <strong>DDD</strong>s are assigned according to the<br />

average daily dose i.e. the total course dose divided by the number<br />

of treatment days (e.g azithromycin).

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