HISTAMINE RECEPTORS

Histaminergics Available from TocrisH Receptor1Agonists0646 HTMT ...........................................................................................H agonistAntagonists0784 Ketotifen .......................................................................................H1antagonist0660 Mepyramine..................................................................................Standard selective H1antagonist0587 2-[4-(2-Methylethyl)phenyl]-3-[3-(N,N-..........................................H1antagonistdimethylamino)propyl]-1,3-thiazolidin-4-one0662 trans-Triprolidine...........................................................................Standard H antagonist, highly potentH Receptor2Agonists0668 Amthamine ...................................................................................Highly selective standard H2agonist0506 Dimaprit ........................................................................................Standard H selective agonistAntagonists0902 Cimetidine ....................................................................................H2 antagonist, I1agonist0833 ICI-162,846...................................................................................Potent H2antagonist, active in vivo0826 Tiotidine ........................................................................................Potent, selective H2antagonist1070 Zolantidine....................................................................................Potent, centrally active H antagonistH Receptor3Agonists0729 Imetit.............................................................................................Standard selective H3agonist0932 Immepip........................................................................................Standard H3agonist0573 N-Methylhistamine ......................................................................Non-selective H3agonist0569 R(-)--Methylhistamine.................................................................Potent and selective standard H3agonist0572 S(+)--Methylhistamine................................................................H agonist, less active enantiomerAntagonists0752 Clobenpropit .................................................................................Highly potent, selective H3antagonist0779 Iodophenpropit .............................................................................Very potent and selective standard H3antagonist0644 Thioperamide ...............................................................................H antagonist, active in vivoHistaminergics - Other0743 DPPE............................................................................................Inhibitor of histamine binding at theintracellular binding site0512 SKF 91488 ...................................................................................Histamine N-methyl transferase inhibitor133122Histamine Receptors, Tocris Reviews No. 6, October 1997,reprinted February 2000Published and distributed by Tocris CooksonEditor: Samantha Manley, Ph.D.Managing Editor: Duncan Crawford, Ph.D.Design and Production: Jane Champness; Lacia Ashman, MAH(0200)Tocris Cookson Ltd.Northpoint Fourth WayAvonmouth BS11 8TA UKTel: + 44 (0)117 982 6551Fax: + 44 (0)117 982 6552customerservice@tocris.co.ukwww.tocris.comtechnicalsupport@tocris.co.ukTocris Cookson Inc.16144 Westwoods Business ParkEllisville MO 63021 USATel: (800) 421-3701Fax: (800) 483-1993customerservice@tocrisusa.com