Hypernatraemia - Nottingham University Hospitals NHS Trust

NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST: Clinical Chemistry Guidelines- OsmolalityUrine (random, no preservative)- Sodium- Potassium- Urea- Creatinine- Osmolality- Dipstick: glucose, ketonesMeasure 24-hour urine excretion if diabetes insipidus is suspected.Further Investigations? Diabetes Insipidus? Conn’s SyndromeIf all common causes of hypernatraemia have been excluded and you suspect DiabetesInsipidus, please contact either a Consultant Endocrinologist or the Duty Biochemist for furtheradvice on investigation and possible water deprivation testing.References1) Sodium. Kumar S, Berl T. The Lancet 1998; 352: 220-229.2) Hypernatraemia. Adrogue HJ, Maclias NE. New England Journal of Medicine 2000;342:1493-1499.Disclaimer:These guidelines have been registered with the Trust. However,clinical guidelines are guidelines only. The interpretation and applicationof the clinical guidelines will remain the responsibility of the individualclinician. If in doubt contact a senior colleague or expert. Caution isadvised when using guidelines after the review date.Created on 18/07/2013 Page 4 of 4