Jul-Sep, 2012 - Indian Journal of Pharmacy Practice

Mahendra Kumar BJ - Drug Induced Syndromes: An Overviewpsychotic, antibiotic, anti-convulsant, anti-thyroid, antiinflammatorydrugs. It has also been described with biologicdrugs (TNF-Α antagonist, adalimumab, infliximab,etanercept), α-Interferon and other cytokines.Symptoms: Fever, cutaneous eruption, lymphadenopathy andhepatosplenomegaly. (Fig 8)Treatment: Cessation of the causative drug is the management39of Pseudolymphoma Syndrome .Gray baby syndrome (Gray or Grey syndrome/GBS):Gray syndrome is a rare but serious side effect occurs innewborn infants (especially premature babies) following theintravenous administration of the antimicrobialchloramphenicol.Causative drug: Chloramphenicol.Symptoms: Vomiting, ashen gray color of the skin, limp bodyFig. 4: Cutaneous necrosisFig. 1: Diffuse erythema on the patient's right armFig. 6: Dry rash, erythema, blistering and desquamationof the palmFig. 2: Blue-gray hyper pigmentation of the face(Blue Gray Syndrome)Fig. 5: Erythematous skin lesionFig. 3: Patient photography shows erythematous exofoliativemaculopapules on the edematous face (A), and polymorphicerythematous maculopapules disseminated on lower legs (B)Indian Journal of Pharmacy Practice Volume 5 Issue 3 Jul - Sep, 2012 17