Novel genetic and epigenetic alterations in ... - Ous-research.no

RØYRVIK ET AL.133. Guanti G, Resta N, Simone C, Cariola F, Demma I, Fiorente P, Gentile M. Involvementof PTEN mutations in the genetic pathways of colorectal cancerogenesis.Hum Mol Genet. 2000;9:283–7.134. Bussaglia E, del RE, Matias-Guiu X, Prat J. PTEN mutations in endometrialcarcinomas: a molecular and clinicopathologic analysis of 38 cases. HumPathol. 2000;31:312–7.135. Cohn DE, Basil JB, Venegoni AR, Mutch DG, Rader JS, Herzog TJ, GersellDJ, Goodfellow PJ. Absence of PTEN repeat tract mutation in endometrialcancers with microsatellite instability. Gynecol Oncol. 2000;79:101–6.136. Dicuonzo G, Angeletti S, Garcia-Foncillas J, Brugarolas A, Okrouzhnov Y,Santini D, Tonini G, Lorino G, De CM, Baldi A. Colorectal carcinomas andPTEN/MMAC1 gene mutations. Clin Cancer Res. 2001;7:4049–53.137. Zhou XP, Loukola A, Salovaara R, Nystrom-Lahti M, Peltomaki P, de la CA,Aaltonen LA, Eng C. PTEN mutational spectra, expression levels, and subcellularlocalization in microsatellite stable and unstable colorectal cancers. Am JPathol. 2002;161:439–47.138. Vilkki S, Launonen V, Karhu A, Sistonen P, Vastrik I, Aaltonen LA. Screeningfor microsatellite instability target genes in colorectal cancers. J Med Genet.2002;39:785–9.139. Iglesias D, Fernandez-Peralta AM, Nejda N, Daimiel L, Azcoita MM, Oliart S,Gonzalez-Aguilera JJ. RIS1, a gene with trinucleotide repeats, is a target in themutator pathway of colorectal carcinogenesis. Cancer Genet Cytogenet.2006;167:138–44.140. Piao Z, Fang W, Malkhosyan S, Kim H, Horii A, Perucho M, Huang S. Frequentframeshift mutations of RIZ in sporadic gastrointestinal and endometrialcarcinomas with microsatellite instability. Cancer Res. 2000;60:4701–4.141. Sakurada K, Furukawa T, Kato Y, Kayama T, Huang S, Horii A. RIZ, the retinoblastomaprotein interacting zinc finger gene, is mutated in genetically unstablecancers of the pancreas, stomach, and colorectum. Genes ChromosomesCancer. 2001;30:207–11.142. Pan KF, Lu YY, Liu WG, Zhang L, You WC. Detection of frameshift mutationsof RIZ in gastric cancers with microsatellite instability. World J Gastroenterol.2004;10:2719–22.143. Hienonen T, Sammalkorpi H, Enholm S, Alhopuro P, Barber TD, Lehtonen R,Nupponen NN, Lehtonen H, Salovaara R, Mecklin JP, Jarvinen H, Koistinen R,Arango D, Launonen V, Vogelstein B, Karhu A, Aaltonen LA. Mutations intwo short noncoding mononucleotide repeats in most microsatellite-unstablecolorectal cancers. Cancer Res. 2005;65:4607–13.254