Novel genetic and epigenetic alterations in ... - Ous-research.no

TARGET GENES OF MSI COLORECTAL CANCERassociated neoplasms with microsatellite instability. Gastroenterology.2005;129:74–85.59. Yamaguchi T, Iijima T, Mori T, Takahashi K, Matsumoto H, Miyamoto H,Hishima T, Miyaki M. Accumulation profile of frameshift mutations duringdevelopment and progression of colorectal cancer from patients with hereditarynonpolyposis colorectal cancer. Dis Colon Rectum. 2006;49:399–406.60. Yamamoto H, Gil J, Schwartz S Jr, Perucho M. Frameshift mutations in Fas,Apaf-1, and Bcl-10 in gastro-intestinal cancer of the microsatellite mutatorphenotype. Cell Death Differ. 2000;7:238–9.61. Ikenoue T, Togo G, Nagai K, Ijichi H, Kato J, Yamaji Y, Okamoto M, Kato N,Kawabe T, Tanaka A, Matsumura M, Shiratori Y, Omata M. Frameshift mutationsat mononucleotide repeats in RAD50 recombinational DNA repair genein colorectal cancers with microsatellite instability. Jpn J Cancer Res.2001;92:587–91.62. Thorstensen L, Holm R, Lothe RA, Trope C, Carvalho B, Sobrinho-Simoes M,Seruca R. WNT-inducible signaling pathway protein 3, WISP-3, is mutated inmicrosatellite unstable gastrointestinal carcinomas but not in endometrial carcinomas.Gastroenterology. 2003;124:270–1.63. Ejima Y, Yang L, Sasaki MS. Aberrant splicing of the ATM gene associatedwith shortening of the intronic mononucleotide tract in human colon tumor celllines: a novel mutation target of microsatellite instability. Int J Cancer.2000;86:262–8.64. Kim NG, Choi YR, Baek MJ, Kim YH, Kang H, Kim NK, Min JS, Kim H.Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene ingastrointestinal carcinomas with microsatellite instability. Cancer Res.2001;61:36–8.65. Ham MF, Takakuwa T, Luo WJ, Liu A, Horii A, Aozasa K. Impairment ofdouble-strand breaks repair and aberrant splicing of ATM and MRE11 in leukemia-lymphomacell lines with microsatellite instability. Cancer Sci.2006;97:226–34.66. Park J, Betel D, Gryfe R, Michalickova K, Di NN, Gallinger S, Hogue CW,Redston M. Mutation profiling of mismatch repair-deficient colorectal cncersusing an in silico genome scan to identify coding microsatellites. Cancer Res.2002;62:1284–8.67. Mongiat-Artus P, Miquel C, Van der AM, Buhard O, Hamelin R, Soliman H,Bangma C, Janin A, Teillac P, van der KT, Praz F. Microsatellite instabilityand mutation analysis of candidate genes in urothelial cell carcinomas of upperurinary tract. Oncogene. 2006;25:2113–8.68. Liu W, Dong X, Mai M, Seelan RS, Taniguchi K, Krishnadath KK, HallingKC, Cunningham JM, Boardman LA, Qian C, Christensen E, Schmidt SS,247