Novel genetic and epigenetic alterations in ... - Ous-research.no

Appendix I – List of abbreviations5-FU – 5’ fluorouracilCEA – carcinoembryonic antigenCIMP – CpG island methylator phenotypeCIN – chromosomal instabilityCpG – Cytosine followed by a guanine, bound with a phosphodiester bindingCRC – colorectal cancerDHLPC – denaturing high performance liquid chromatographyDNA – deoxyribonucleic acidDNMT – DNA methyl transferaseFAP – familial adenomatous polyposisFOBT – faecal occult blood testHNPCC – hereditary non-polyposis colorectal cancerHP – hyperplastic polypMAP – mitogen activated proteinMBD – methyl binding domainMLPA – multiplex ligation-dependent probe amplificationMMR – DNA mismatch repairMSI – microsatellite instabilityMSP – methylaton-specific polymerase chain reactionMSS – microsatellite stablePCR – polymerase chain reactionRNA – ribonucleic acidRT-PCR – real time polymerase chain reactionTEA – triethylammonium ionWNT – Wingless-type MMTV integration site family