il programma - Istituto di Ricerche Farmacologiche Mario Negri

ACCREDITAMENTO ECM RICHIESTO (Medico Chirurgo - Infermiere)Weil ConferenceConference onCardiac Arrest,Shock and TraumaSave Patients Lives Through Researchin Critical Care and EducationIstituto Mario Negri8-9 September 2012 - Milan, Italy1

Sponsored By:WEIL CONFERENCE - Organizing & Scientific CommiteeGullo AntoninoDipartimento di Anestesia e Rianimazione, Università degli Studi di CataniaKette FulvioResponsabile “Coordinamento Clinico del Soccorso Sanitario”AREU – Azienda Sanitaria Emergenza Urgenza LombardiaPellis TommasoStruttura Complessa di Anestesia, Rianimazione e Terapia Intensiva,Azienda Ospedaliera Santa Maria degli Angeli, PordenoneRistagno GiuseppeDipartimento di Ricerca Cardiovascolare, Farmacologia Clinica Cardiovascolare,Istituto di Ricerche Farmacologiche Mario Negri, MilanoZoli AlbertoDirigente Generale, AREU – Azienda Sanitaria Emergenza Urgenza LombardiaWEIL CONFERENCE – Organizing SecretariatStart PromotionVia Mauro Macchi, 50 - 20124 MILANOPh: +39 02 67071383 - Fax: +39 02 67072294E-mail:info@startpromotion.it3

WEIL CONFERENCE - FacultyA. ArcadipaneDipartimento di Anestesia e Rianimazione,ISMETT, PalermoG. BerlotAnestesia e Rianimazione TerapiaAntalgica, Ospedale di Cattinara, TriesteG. BertoliniDipartimento di Salute Pubblica, Istitutodi Ricerche Farmacologiche Mario Negri,Ranica (BG)B. BöttigerDepartment of Anesthesiology andIntensive Care Medicine, UniversityHospital, University of Cologne,Cologne, GermanyG. CammarataDipartimento di Anestesia e Rianimazione,Ospedale Vittorio Emanuele, CataniaM. CastrénDepartment of Clinical Sciences andEducation, Karolinska University Hospital,Stockholm (S)E. CerchiariAnestesia e Terapia Intensiva, AUSLOspedale Maggiore, BolognaR. De GaudioIstituto di Anestesiologia e Rianimazione,Università degli Studi di Firenze, AziendaOspedaloero-Universitaria Careggi, FirenzeD. FriesDepartement of Anestesia, University ofAachen (D)R. FumagalliStruttura Complessa di Anestesia eRianimazione 1, Azienda OspedalieraNiguarda Cà Granda, MilanoS. GarattiniDirettore, Istituto di RicercheFarmacologiche Mario Negri, MilanoL. GattinoniDipartimento di Anestesiologia, TerapiaIntensiva e Scienze Dermatologiche, Universitàdegli Studi di Milano, Fondazione IRCCS CàGranda Ospedale Maggiore Policlinico, MilanoR. J. GazmuriDirector Resuscitation Institute, RosalindFranklin University, Chicago, USAA. GulloDipartimento di Anestesia e Rianimazione,Università degli Studi di CataniaE. J. JimenezDepartment of lntensive Care, Orlando,Florida, USAK. KernSection of Cardiology, Cardiac Catheterization,Sarver Heart Center, University of Arizona (USA)F. KetteResponsabile “Coordinamento Clinicodel Soccorso Sanitario”, AREU – AziendaSanitaria Emergenza Urgenza LombardiaR. LatiniDipartimento di Ricerca Cardiovascolare,Istituto di Ricerche Farmacologiche MarioNegri, Milano4

WEIL CONFERENCE - FacultyG. Li VoltiFacoltà di Farmacia, Università degli Studidi CataniaP. LumbDepartment of Anesthesiology, Universityof Southern California, Los Angeles, USAS. MentzelopoulosIntensive Care Medicine, University ofAthens, Department of Intensive CareMedicine, Evanggelismos General Hospital,AthensP. MurabitoDipartimento di Anestesia e Rianimazione,Università degli Studi di CataniaN. NielsenDepartment of Anesthesiology andIntensive Care, Helsingborg Hospital,Helsingborg, SwedenM. NocCenter for Intensive Internal Medicine,Ljubljana, SloveniaJ. NolanAnaesthesia and Intensive Care Medicine,Royal United Hospital NHS Trust, Bath, UKC. OriDipartimento di Anestesia e Rianimazione,Università degli Studi, PadovaT. PellisStruttura Complessa di Anestesia, Rianimazionee Terapia Intensiva, Azienda Ospedaliera SantaMaria degli Angeli, PordenoneA. PesentiDipartimento di Emergenza e Urgenza,Terapia Intensiva Generale, Università diMilano Bicocca, Azienda Ospedaliera SanGerardo, MonzaG. RistagnoDipartimento di Ricerca Cardiovascolare,Farmacologia Clinica Cardiovascolare,Istituto di Ricerche Farmacologiche MarioNegri, MilanoC. SandroniU.O.C. Pronto Soccorso, Anestesia eRianimazione, Università Cattolica delSacro Cuore, Policlinico A. Gemelli, RomaG. SgangaDipartimento di Chirurgia Generale deiTrapianti D’Organo, Università Cattolicadel Sacro Cuore RomaW. TangWeil Institute of Critical Care Medicine,California, USAG. TognoniDirettore Consorzio Mario Negri Sud, ChietiR. WhiteDepartment of Internal Medicine, Divisionof Cardiovascular Diseases, Mayo ClinicCollege of Medicine, Rochester, USAL. WikNational Competence Center of EmergencyMedicine, Oslo University, Norway5

WEIL CONFERENCE - Program September 8 th09.00 Opening AddressChairpersons: G. Ristagno, A. GulloWelcome address: S. Garattini, E. Jimenez, P. Lumb09.30 State of the Art in Critical Care- Cardiac Arrest: Fifty Years From the Lab to Clinical Trials - W. Tang- Tribute to Max Harry Weil, the Father of Critical Care. From the beggining ofCritical Care to the Present State of the Art - A. Gullo- Guidelines, Recommendations and Planning Strategy in Trauma Care - P. Lumb- Quality of Care Assessment & Improvement: The GiViTI Experience - G. Bertolini- Discussion: R. Gazmuri, A. Gullo, P. Murabito, M. Noc, G. Sganga11.00 Coffee Break11.30 Quality of CPR- Chest Compression Only vs Chest Compression Plus Ventilation - M. Castren- Manual vs Mechanical Chest Compression - L. Wik- Utstein Style and quality of CPR - E. Cerchiari- Discussion: M. Fries, R. Gazmuri, A. Gullo, J. Jimenez, T. Pellis, W. Tang13.00 Lunch14.30 Advances on Defibrillation- Priorities of Intervention: Chest Compression vs Defibrillation - W. Tang- Predictors of Success of Defibrillation - G. Ristagno- Ventricular Fibrillation and Defibrillation: State of Our Knowledge and Uncertainties - R. White- Discussion: G. Berlot, K. Kern, F. Kette, R. De Gaudio, S. Sun, L. Wik16.00 Invited lectureComparison of currently available AEDs - F. Kette16.30 Coffee Break17.00 Optimization of CPCR Procedures on Sudden Cardiac Death- Optimized Approach in Cardiocerebral Resuscitation - K. Kern- Reperfusion Strategies of Sudden Cardiac Death - M. Noc- ECMO Strategy in Cardiac Arrest - R. Fumagalli- Discussion: A. Arcadipane, M. Fries, E. Jimenez, P. Lumb, A. Pesenti, W. Tang6

WEIL CONFERENCE - Program September 9 th08.30 Pharmacological Approach during CPR- Vasopressor during CPR - C. Sandroni- Targeting Mitochondria during CPR - R. Gazmuri- The potential contribution of corticosteroids to positive cardiacarrest outcomes - S. Mentzelopoulos- Discussion: G. Cammarata, J. Jimenez, K. Kern, G. Li Volti, R. Latini, R. White10.00 Invited LectureTranslational Research: Current Status, Challenges, andFuture Strategies - G. Tognoni10.20 Coffee Break10.50 Post-resuscitation Care- Effectiveness of Hypothermia in Human Cardiac Arrest - T. Pellis- Update on TTM Trial - N. Nielsen- New Strategies to Improve Outcome after Cardiac Arrest - M. Fries- Predicting Outcome of Cardiac Arrest - B. Bottiger- Discussion: M. Castren, R. Gazmuri, K. Kern, C. Ori, W. Tang12.20 Invited LectureFrom Experimental and Clinical Evidence to Guidelines - J. Nolan12:45 Combining Physiology, Clinical Outcome, Education, and Research- Role of central venous saturation monitoring - L. Gattinoni- Education and Research in Critical Care - P. Lumb13.25 Closing Remarks G. Ristagno7

WEIL CONFERENCE - General InformationTHE VENUEThe venue of the “WEIL CONFERENCE - Conference on Cardiac Arrest, Shock and Trauma”is the Mario Negri Institute. The Mario Negri Institute for Pharmacological Research is anot-for-profit biomedical research organization. It was founded in 1961, and startedwork in Milan on 1 February 1963. There are now research units in Bergamo, at Ranica– near Bergamo – and at Santa Maria Imbaro, near Chieti.Address:Istituto di Ricerche Farmacologiche “Mario Negri”Via Giuseppe La Masa, 19 - 20156 MilanoPh: +39 02 390141 - Fax: +39 02 3546277E-mail: mnegri@marionegri.it - Website: www.marionegri.itREGISTRATION FEERegistration Fees:- Doctors: € 200,00*- Nurses and IRC member: € 150,00*- Resident: €100,00**VAT 21% includedPre-registrations should be done online within August 31st.Registration Fee includes:Congress bag - Badge - Attendance Certificate - Coffee Break - LunchRegistration must be done in electronic format at www.startpromotion.itPAYMENT INSTRUCIONSPayment of the registration fee can be made as follows:• Bank transfer (free of charge for the beneficiary) to:START PROMOTION SrlBank: INTESA SANPAOLO Spa - Agenzia di PaviaSWIFT/BIC Code: BCI TIT MMIBAN: IT21X0306911310000027269163As payment description, please indicate: WEIL 2012, first & family name of the registrant.A copy of the payment document (bank transfer) must be faxed in advance to theOrganizing Secretariat (fax no: +39 02 67072294). The invoice will be sent to theaddress specified during online registration at www.startpromotion.it.Receipt of invoice will confirm registration.8

WEIL CONFERENCE - General InformationABSTRACT SUBMISSIONParticipants are invited to submit scientific papers on Cardiac Arrest, Shock and Traumaas posters. Please read carefully the instructions below before forwarding your abstract.Authors are required to submit their abstracts to the Organizing Secretariat prior toJuly 31, 2012. Abstracts may only be submitted online at www.stratpromotion.it.After a correct submission, a confirmation message will be automatically sent to youremail address (within August 3). At least one of the Authors is required to be aregistered participant to the WEIL Conference. Please DON’T try to submit the sameabstract more than once. Should you find errors after submission, please refer to theOrganizing Secretariat (info@startpromotion.it).Abstract submission is possible through the online procedure only. Abstracts sent byfax or mail will not be accepted. All the abstracts received will be evaluated by theScientific Committee, which will decide whether to accept them as posters. Contactswith the Authors will be only by email. Please verify that your email address has beencorrectly typewritten during the registration procedure and don’t forget to check youremail account regularly.REGISTRATION DESKThe registration desk is located in the main hall of Istituto Mario Negri.Opening hours:Saturday, 8 September 8.00-18.00 hrsSunday, 9 September 8.00-16.00 hrsPre-registered delegates will receive the congress materials upon their arrival.CONGRESS LANGUAGEAll sessions of the scientific program are in English with simultaneous translation English/Italian.BADGESDelegates will receive a name badge on registration time. The badge must wornprominently in order to gain access to the congress area during all scientific and socialevents. Admission will be refused to anyone not in possession of an appropriate badge.POSTER PRESENTATIONSPosters will be affixed in the Poster Area - Main Floor from 09.30 a.m. of September8 to 14.30 p.m. of September 9. Authors are required to be next their own postersduring the coffee breaks. POSTER SIZE: 120 cm (Height) - 80 cm (Base)9

WEIL CONFERENCE - How to get to Mario Negri?by AEROPLANEMilan is easily reachable from THREE INTERNATIONAL AIRPORTS: MILANO LINATE (near to thedowntown), MILANO MALPENSA (40 km) and ORIO AL SERIO (50 km, near to Bergamo).Together they ensure frequent domestic and international connections.MILANO MALPENSAMALPENSA is the largest airport in the Milanese area and it has two terminals at its disposal thatensure domestic and International connections, as well as numerous intercontinental flights. Theairport is well connected with the Lombard capital. The journey takes roughly one hour by car on theA8 autostrada (motorway). There are also shuttle services (Malpensa Bus Express, Malpensa ShuttleAir Pullman) that connect it with Stazione Centrale (Central Station) and Linate Airport. It is alsoconnected by train to the downtown to Cadorna station (Malpensa Express Ferrovie Nord Milano).10

WEIL CONFERENCE - How to get to Mario Negri?From Malpensa to istituto Mario Negri: take the train called MALPENSA EXPRESS (price for onewayticket is 11 euros) to the downtown: get off at the station MILANO NORD BOVISA POLITECNICO,which is very close to the Istituto Mario Negri. Exiting the Bovisa Politecnico station you should takethe stairs on the right and reach the main road. Take the left and follow the road, then take thefirst road on the right. After 100 m. take the first road on the left and the Istituto Mario Negri willbe right in front of you (5 minutes walk). www.milanomalpensa1.eu - www.milanomalpensa2.euMILANO LINATELINATE is a city airport, very close to the centre. In just a few minutes passengers can arrive inPiazza San Babila with the urban bus line number 73. Linate is also serviced by private shuttlebuses that link the airport with Stazione Centrale (Central Station), Fiera Milano city, Rho faircentre and also Malpensa airport (Starfly, Air Pullman Noleggi, and Malpensa Shuttle Air Pullman).From Linate to istituto Mario Negri: you can use TAXI or BUS 73 to Piazza San Babila, in the centreof Milan, where you can take the UNDERGROUND LINE 1 (also called RED LINE; price for a ticketis 1.5 euros and the ticket is valid for 90 minutes after first usage, also on suburban railways) tothe CADORNA railway station. All trains leaving Cadorna station stop at the MILANO NORD BOVISAPOLITECNICO STATION (see the box above for indications from this stop to Istituto Mario Negri).www.milanolinate.euMILANO ORIO AL SERIOORIO AL SERIO approximately one hour’s travel from Milan, is well connected with the city centre. Itcan be reached by car in autostrada (motorway) Milano-Venezia A4 or by shuttle bus (Autostradale,Locatelli Air Pullman) that connects it with Stazione Centrale (Central Station), Milan. For those thatarrive or depart in train, Bergamo’s Stazione Centrale can be reached using buses that depart everyten minutes to and from the airport.From Orio al Serio to istituto Mario Negri: take a SHUTTLE BUS to the STAZIONE CENTRALE, fromwhere you can use the UNDERGROUND LINE 2 (also called GREEN LINE; price for a ticket is 1.5euros and the ticket is valid for 90 minutes after first use, also on Trenord - Ferrovie Nord Milanorailways) to get the CADORNA railway station. Then, to reach the istituto Mario Negri, take a trainto the MILANO NORD BOVISA POLITECNICO STATION (see the Malpensa box above for indicationsfrom this stop to Istituto Mario Negri).11

WEIL CONFERENCE - How to get to Mario Negri?by TRAINMilan has numerous railway stations at its disposal, the most important being CENTRALE,LAMBRATE and GARIBALDI.From STAZIONE CENTRALE (Central Station) trains depart for all Italian and Europeandestinations, while the others function as an important hub for regional services.Furthermore, in the middle of the city, beside Castello Sforzesco (Sforza Castle), there isCADORNA STATION. It is managed by the Ferrovie Nord group and represents an importantregional railway siding.This network, also used by the PASSANTE FERROVIARIO, which functions in a similar mannerto an urban underground line and services numerous underground stations in the centreof Milan, such as Repubblica and Garibaldi Passante. Moreover, it connects the city withimportant tourist locations and the international airport Malpensa. With the Trenord railway,trains run to Como station, just a short distance from the lake, as well as Canzo in upperBrianza, Varese and Laveno on Lake Maggiore.From Cadorna Station to istituto Mario Negri: take a train (price for a ticket is 1.5 euros) to theMILANO NORD BOVISA POLITECNICO STATION, which is very close to the Istituto Mario Negri.All trains leaving Cadorna station stop there. Exiting the Bovisa Politecnico stop you shouldtake the stairs on the right and reach the main road. Take the left and follow the road, thentake the first road on the right. After 100 m. take the first road on the left and the IstitutoMario Negri will be right in front of you (5 minutes walk). www.trenord.itFrom Central Station to istituto Mario Negri: take the UNDERGROUND LINE 2 (also calledGREEN LINE; price for a ticket is 1.5 euros and the ticket is valid for 90 minutes after first use,also on Trenord - Ferrovie Nord Milano railways) to get the CADORNA railway station. Then, toreach the Istituto Mario Negri, take a train to the MILANO NORD BOVISA POLITECNICO STATION(see above). www.atm-mi.it – www.trenord.it12

WEIL CONFERENCE - How to get to Mario Negri?If you are already in MilanThe easiest way to get the Istituto Mario Negri is taking a train (price for a ticket is 1.5 euros)from CADORNA STATION to the MILANO NORD BOVISA POLITECNICO STATION. All trains leavingCadorna station stop there. Exiting the Bovisa Politecnico stop you should take the stairs onthe right and reach the main road. Take the left and follow the road, then take the first roadon the right. After 100 m. take the first road on the left and the Istituto Mario Negri will beright in front of you (5 minutes walk).In alternative, you can take a train from GARIBALDI STATION to the MILANO NORD BOVISAPOLITECNICO STATION using the PASSANTE FERROVIARIO, which is similar to an urbanunderground line.13

The WEIL CONFERENCE is supported byunrestricted grants provided by:Platinum Sponsor