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Mohammed T. Abou-Saleh

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THE EPIDEMIOLOGY OF ALZHEIMER’S DISEASE: AN UPDATE 207besides age and the apolipoprotein gene, few risk factors havebeen shown consistently to reduce, or to increase, the risk for AD.With advances in our understanding of the brain and our geneticcode, rapid progress should be made in identifying environmentaland genetic risk factors and in studying the interaction betweenthe two.REFERENCES1. The National Institute on Aging, and Reagan Institute WorkingGroup on Diagnostic Criteria for the Neuropathological Assessmentof Alzheimer’s Disease. Consensus recommendations for thepostmortem diagnosis of Alzheimer’s disease. Neurobiol Aging 1997;18(4 Suppl): S1–2.2. Skoog I, Lernfelt B, Landahl et al. 15-year longitudinal study ofblood pressure and dementia. Lancet 1996; 347: 1141–5.3. Ross GW, Abbott RD, Petrovitch H et al. Frequency andcharacteristics of silent dementia among elderly Japanese-Americanmen. The Honolulu–Asia Aging Study. J Am Med Assoc 1997; 12:800–5.4. 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