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Peripheral nerve stimulation - Outcome Medical of Georgia

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J. N. Campbell and D. M. Longrote <strong>of</strong> central effects as meansby whichelectrical <strong>stimulation</strong> relievespain thereforeremainsunsettled.Conclusionsas to the role <strong>of</strong> peripheral<strong>nerve</strong> <strong>stimulation</strong> in the treatment <strong>of</strong> chronicpain can only be made tentatively. In selectgroup<strong>of</strong> patientsin thisseriesthismode <strong>of</strong>treatment has provided relatively safeeffective means<strong>of</strong> controlling pain. Thissuccessis evidenced by pain relief imin lifeprovementsstyle cessation <strong>of</strong> narcoticintake normalization <strong>of</strong> sleep-wake cyclesand improvement in psychological well-beingwith no disturbance <strong>of</strong> other neurologicalfunctions. The most promising group <strong>of</strong>patientsfor thismode <strong>of</strong> treatmentappearstobe those with peripheral <strong>nerve</strong> injurieswhich the <strong>stimulation</strong> can be attached to theaffected <strong>nerve</strong> at point proximal to the site<strong>of</strong> injury. The incidence <strong>of</strong> complicationsappearsto be relatively low. The use <strong>of</strong> sciatic<strong>nerve</strong> stimulatorsin the treatment <strong>of</strong> the lowback pain syndrome and painfrom metastaticdisease is not advocated for in our seriesthesepatientshave done poorly. Futureresearch will be directed toward determiningthe safety <strong>of</strong> thistechnique and its mechanism<strong>of</strong> action and toward better definition <strong>of</strong>the patient population that will respondfavorably to its use.References1. Accornero Bini Manfredi Differential block <strong>of</strong> cutaneous<strong>nerve</strong> fiberswith triinangularly shaped electrical impulses. Presented at the First World Congress<strong>of</strong> theInternational Association for the Study <strong>of</strong>Pain Florence Italy September 19752. Bessou Perl ER Response <strong>of</strong> cutaneoussensory unitswith unmyelinated fibersto noxiousstimuli. Neurophysiol 321025104319693. Campbell 3M Local analgesia froni percutaneouselectrical <strong>stimulation</strong> andperipheral mechanism. M.D. thesisUniversity 1973Yale4. Campbell 3M. Taub Local analgesia fromelectrical <strong>stimulation</strong>.percutaneousperipheral mechanism. Arch Neurul 23347350 19735. Hodge Ci ir Potential changesinside centralafferentterminals secondary to <strong>stimulation</strong><strong>of</strong>large- and small-diameter peripheral <strong>nerve</strong>fibers. Neurophysiol 353043 19726. Long DM Electrical <strong>stimulation</strong> for rclicf <strong>of</strong>pain from chronic <strong>nerve</strong> injury. Neurosurg3971S722 19737. Long DM External electrical <strong>stimulation</strong> astreatmcnt <strong>of</strong> chronic pain. Minn Med 57195198. 19748. Long DM Erickson DE Stimulation <strong>of</strong> theposterior<strong>of</strong>1975intractablecolumns<strong>of</strong> the spinal cord for reliefpain. Surg Neurol 41341419. Manfredi Modulation <strong>of</strong> sensory projectionsin anterolateral column <strong>of</strong> cat spinal cordby peripheral afferents<strong>of</strong> different size. Archhal Biol 10872lOS1970 Eng10. Melzack Wall PD Pain mechanismsnew theory. Science 150971979 196511. Mendell Properties and distribution <strong>of</strong>.peripherally evoked presynaptic hyperpolarization in cat lumbar spinalcord. PhyslolLond 226769792 197212. Meyer GA FieldsIlL Causalgia treated byselectivelarge<strong>nerve</strong>. Brain 95163168 1972fibre <strong>stimulation</strong> <strong>of</strong> peripheral13. Nashold BS Jr Friedman Dorsal column<strong>stimulation</strong> for control <strong>of</strong> pain. Preliminaryreport on 30 patients. Neurosurg36590597 197214. Picaza JA Cannon BW Hunter SE ct alPain suppression by peripheral <strong>nerve</strong> <strong>stimulation</strong>. Part I. Observationswith implanteddevices. Surg Neurol 4115126 197515. Pineda Dorsal column <strong>stimulation</strong> and itsprospects. Surg Neurol 4157163 197516. Shealy CM Dorsal column <strong>stimulation</strong> optimization <strong>of</strong> application. Surg Neurol4142145 197517. Shealy CM Mortimer JT HagforsNR Dosal column clectroanalgesia. Neurosurg32560564 197018. Sweet WH Wepsic JO Stimulation <strong>of</strong> theposteriorcontrolcolumns<strong>of</strong> the spinal cord for painindicationsClin Neurosurg 212783 10 1974techniquesand results.19. Sweet WH Wcpsic JO Treatment <strong>of</strong> chronicpain by <strong>stimulation</strong> <strong>of</strong> fibers<strong>of</strong> primaryafferent neurons. Trans Am Neurol Asset93103107 196820. Taub Electrical <strong>stimulation</strong> for the relief <strong>of</strong>pain two lessonsin technological zealotry.Perspect Biol Med 19125135 Autumn 197521. Torebjork HE Hallin RO Responseshuman and fibersto repeatedinelectrical intradermal <strong>stimulation</strong>. Neurol NeurosurgPsychiatry 37653664 197422. Wngman III Price DD Respntses<strong>of</strong> dorsalhorn celis<strong>of</strong> Af. mulatto to cutaneousand aural <strong>nerve</strong> and fiber stimuli. Neurophysiul32802817 196923. Wall PD Dorsal horn electrophysiology inIggo ed Handbook <strong>of</strong> Sensory PhysiologyVolume Soniatosensory System. BerlinSpringer-Vcrlag 1973 pp 253270698J.Peurosurg. Volume 43 0fjnbcr.1976

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