Dr. Derk Joester - Northwestern University

Curriculum Vitae Joester 1/7Dr. Derk JoesterMaterials Science and Engineering T: +1 847 491 7443Cook Hall, 2220 Campus Drive F: +1 847 491 7820Evanston, IL 60208, USAd-joester@northwestern.eduAPPOINTMENTS09/2011- Assistant Professor, Materials Science and Engineering, NorthwesternUniversity, Evanston, IL 60208.09/2009-08/2011 Morris E. Fine Professor of Materials and Manufacturing,Materials Science and Engineering, Northwestern University, Evanston, IL60208.09/2007- Assistant Professor, Materials Science and Engineering, NorthwesternUniversity, Evanston, IL 60208.RESEARCH AND TEACHING EXPERIENCE07/2005-06/2007 Minerva Fellow, Dept. Struct. Biol., Weizmann Institute of Science,Rehovot, Israel.Advisers: Profs. L. Addadi, B. Geiger (Dept. Molecular Cell Biology), andM. Elbaum (Dept. Materials and Interfaces).06/2003-06/2005 Postdoctoral Fellow, Dept. Struct. Biol., Weizmann Institute of Science,Rehovot, Israel.Advisers: Profs. L. Addadi and B. Geiger (Dept. Mol. Cell Biol.)09/1998-03/2003 Research Assistant, Dept. of Organic Chemistry, ETH Zürich,Switzerland.Adviser: Prof. F. Diederich09/1998-03/2001 Teaching Assistant, Dept. of Organic Chemistry, ETH Zürich,Switzerland.EDUCATION09/1998-03/2003 Ph.D. student, Dept. Organic Chemistry, ETH Zürich, Switzerland.Adviser: Prof. F. Diederich.Ph.D. Thesis: “Amphiphilic Dendrimers: Novel Self-Assembling Vectorsfor Gene Delivery.”10/1995-06/1998 Dept. Organic Chemistry, ETH Zürich, Switzerland.Advisers: Dr. T. Carell, Prof. F. Diederich.Diploma Thesis: “Synthesis of Model Compounds of Type-II DNA-Photolyases.”08/1994-07/1995 Fulbright Scholar, University of Tennessee,Knoxville TN, USA.10/1992-07/1994 Dept. of Chemistry, University of Tübingen, Germany.

Curriculum Vitae Joester 2/7PRACTICAL TRAINING AND JOB EXPERIENCE08/2000-09/2000 Participant, 99 th BASF Summer Course, BASF AG,Ludwigshafen, Germany.07/1998-08/1998 Student Researcher, Bayer AG, Leverkusen, Germany.02/1997-04/1997 IAESTE Trainee, The Lipid Research Institute, University ofAlberta, Edmonton, Canada.Adviser: Prof. Vance01/1990-12/1991 Lab Technician, Bioferon GmbH, Laupheim, Germany.AWARDS/SCHOLARSHIPS2009-2011 Morris E. Fine Professor in Materials and Manufacturing2008 Searle Junior Fellow Program Award 2008/20092006 Full Scholarship at the GEM 4 Summer School, MIT, Cambridge, MA.JSP Fellow at the Bürgenstock Conference on Stereochemistry.2005-2007 Minerva Postdoctoral Fellowship.2003-2005 Friends of the Weizmann-Institute Postdoctoral Fellowship.1999-2000 ETH-Scholarship.1994-1995 Fulbright-Scholar.

Curriculum Vitae Joester 3/7PUBLICATIONS2011 M. R. Krejci, B. Wasserman, L. Finney, I. McNulty, D. Legnini, S. Vogt, and D.Joester, J. Struct. Biol. 2011, 176, 192-202, “Selectivity in biomineralization ofbarium and strontium.” DOI: 10.1016/j.jsb.2011.08.006.C. C. Tester, R. E. Brock, C.-H. Wu, M. R. Krejci, S. Weigand, and D.Joester, CrystEngComm 2011, 13, 3975-3978, “In vitro synthesis andstabilization of amorphous calcium carbonate (ACC) nanoparticles withinliposomes.” DOI: 10.1039/C1CE05153A.M. R. Krejci, L. Finney, S. Vogt, and D. Joester, ChemSusChem 2011, 4,470-473. “Selective sequestration of strontium in desmid green algae bybiogenic co-precipitation with barite”. DOI: 10.1002/cssc.201000448.C.-H. Wu, A. Park, and D. Joester, J. Am. Chem. Soc. 2011, 33, 1658–1661, “Bioengineering Single Cystal Growth”. DOI: 10.1021/ja109500e.L. Gordon, D. Joester, Nature 2011, 469, 194-197, “Nano-Scale ChemicalTomography of Buried Organic- Inorganic Interfaces in the Chiton Tooth.”DOI:10.1038/nature09686.2007 M. Guillot-Nieckowski, D. Joester, M. Stöhr, M. Losson, M. Adrian, B.Wagner, M. Kansy, H. Heinzelmann, R. Pugin, F. Diederich, J.-L. Gallani.Langmuir 2007, 23, 737-746. “Self-assembly, DNA complexation, and pHresponse of amphiphilic dendrimers for gene transfection”.M. Cohen, D. Joester, B. Geiger, L. Addadi. Soft Matter 2007, 3, 327-332.“Hyaluronan in the pericellular coat: an additional layer of complexity inearly cell adhesion events.”2006 D. Joester, E. Klein, B. Geiger, L. Addadi. J. Am. Chem. Soc. 2006, 128,1119-1124. “Temperature-sensitive micrometer-thick layers of hyaluronangrafted on microspheres”.L. Addadi, D. Joester, F. Nudelman, S. Weiner, Chem. Eur. J. 2006, 12,980-987. “Mollusk shell formation: A source of new concepts forunderstanding biomineralization processes”.2004 D. Joester, V. Gramlich, F. Diederich, Helv. Chim. Acta. 2004, 87, 2896-2918. “Amphiphilic dendrimers with heteroleptic bis([2,2':6',2"]terpyridine)-ruthenium(II) cores”.M. Cohen, D. Joester, B. Geiger, L. Addadi, ChemBioChem 2004, 5, 1393-1399. “Spatial and temporal sequence of events in cell adhesion: Frommolecular recognition to focal adhesion assembly”.C. Minelli, N. Blondiaux, M. Losson, M. Liley, S. Jeney, C. Hinderling, R.Pugin, D. Joester, F. Diederich, J. Vancso, M. Hempenius, H.Heinzelmann, Chimia 2004, 57, 646-650. “Nano-structuring by molecularself-assembly”.2003 D. Joester, M. Losson, R. Pugin, H. Heinzelmann, E. Walter, H. P. Merkle,and F. Diederich, Angew. Chem. Int. Ed. 2003, 42, 1486-1490; Angew.Chem. 2003, 115, 1524-1528. “Amphiphilic dendrimers: Novel selfassemblingvectors for efficient gene delivery”.

Curriculum Vitae Joester 4/7PRESENTATIONS 2006-20122012 Gordon Research Conference on Biomineralization, Colby Sawyer College,New London, NH. Invited Talk titled: “TBA”.American Physical Society March Meeting 2012, Boston, MA. Invited Talktitled: “TBA”.Materials Research Society Spring Meeting 2012, San Francisco, CA. Invitedtalk titled: “TBA.”2011 University Konstanz, Konstanz, Germany. Seminar talk titled: “AppliedBiomineralization: Crystal Growth Control and Sequestration of Strontium.”ETH Zurich, Zurich, Switzerland. Talk titled: “Nanoscale ChemicalTomography of Biominerals.”Materials Research Society Fall Meeting 2011, Boston, MA. Invited talktitled: “Chemical Nanotomography of Biomineral Nanocomposites.” Talk titled:“In vitro Synthesis and Stabilization of Amorphous Calcium Carbonate (ACC)Nanoparticles within Liposomes.”BASF Insights, Ludwigshafen, Germany.Washington University, St. Louis, Mo. Seminar talk titled: “ReverseEngineering Biological Crystal Growth.”Princeton University, Princeton, NJ. Seminar talk titled: “Reverse EngineeringBiological Crystal Growth.”Composites at Lake Louise, Lake Louise, Alberta, Canada. Invited talk titled:“Chemical Nano-Structure and Biological Processing of Biominerals.”48th Annual Technical Conference of Society of Engineering Sciences 2011(SES2011), Northwestern University, Chicago, IL. Talk titled: “Atom probetomography of buried organic-inorganic interfaces in biological minerals” –presented by Lyle Gordon; Talk titled: “Bioengineering structural andmechanical properties of the sea urchin larval spicules.” – presented by Ching-Hsuan Wu.Ohio State University, Columbus, OH. Invited talk titled: “Reverse EngineeringBiological Crystal Growth.”American Chemical Society Fall 2011 National Meeting and Exposition,Denver, CO. Talk titled “Synthesis and stabilization of amorphous calciumcarbonate within liposomes” – presented by Chantel Tester.International Summer School: Cellular Systems, Ruprecht-Karls-UniversityHeidelberg, Germany. Talk titeled: "Controlling single crystal growth withrecombinant sea urchin VEGF " – presented by Regina KnappGordon Research Conference on Thin Films and Crystal GrowthMechanisms, University of New England, Biddeford, ME. Talk titled: “ReverseEngineering Biological Crystal Growth.”11 th International Symposium on Biomineralization 2011, Queensland,Australia. Talk titled: “Bioengineering Single Crystal Growth”; Talk titled:“Buried organic-inorganic interfaces in biological minerals” – presented by

Curriculum Vitae Joester 5/7Lyle Gordon; Talk titled: “Selectivity in Biomineralization of Barium andStrontium in Desmid Green Algae.” – presented by Minna Krejci.Tenth International Conference on Materials Chemistry (MC10) 2011,Manchester, UK. Talk titled "In vitro synthesis and stabilization of amorphouscalcium carbonate (ACC) nanoparticles within liposomes". Talk titled"Bioengineering Single Crystal Growth". Poster titled "Nano-Scale ChemicalTomography of Buried Organic-Inorganic Interfaces".Cellular Nanoscience Conference, University of Heidelberg, Heidelberg,Germany. Talk titled: “Bioengineering Single Crystal Growth.” – presented byChing-Hsuan Wu.Enamel VIII, Starved Rock Lodge, Utica, IL. Poster titled: “NanoscaleChemical Tomography of Tooth Enamel and Invertebrate Tooth Models.”American Chemical Society Spring 2011 National Meeting and Exposition,Anaheim, CA. Talk titled: “Selective Sequestration of Strontium and Barium viaBiomineralization in Desmid Green Algae.” – presented by Minna Krejci.2011 Argonne National Laboratory APS/CNM/EMC Users Meeting,Argonne, IL. Invited talk titled: “Strontium Sequestration in Biominerals: FromCellular Dynamics to Probing Local Structure Evolution.” Poster titled: “2Dand 3D X-ray Fluorescence Microscopy of Strontium Uptake and Mineralizationin Green Algae.” – presented by Minna Krejci. Poster titled “Synthesis andstabilization of amorphous calcium carbonate within liposomes” – presented byChantel Tester.University of Southern California, Los Angeles, CA. Seminar talk titled:“From Ions and Molecules to Functional Tissues: Bioengineering Single CrystalGrowth and Chemical Nanotomography of Biominerals”.Molecular Foundry, Lawrence Berkeley National Lab, Berkeley, CA.Seminar talk titled: “From Ions and Molecules to Functional Tissues:Bioengineering Single Crystal Growth and Chemical Nanotomography ofBiominerals”.American Physical Society March Meeting 2011, Dallas, Texas. Invited talk(New Directions in Biological Physics Tutorial) titled: “Biomineralization: howliving organisms harness physical and chemical mechanisms to form their hardbiomineral skeletons.”Max Planck Institute Stuttgart, Stuttgart, Germany. Seminar talk titled:“Bionegineering Single Crystal Growth”.Hybrid Materials 2011, Strasbourg, France. Talk titled: “Bioengineering SingleCrystal Growth.” Poster titled: “Atom Probe Tomography of Buried Organic-Inorganic Interfaces in Biominerals.”2010 International Conference on the Chemistry and Biology of MineralizedTissues (ICCBMT), Carefree, AZ. Talk titled: “Atom Probe Tomography ofBuried Organic-Inorganic Interfaces in Biominerals.”Osaka-Northwestern Workshop on Advanced Structural and FunctionalMaterials Design, Osaka, Japan. Talk titled: “Bioengineering Single CrystalGrowth.”17 th International Microscopy Congress, Rio de Janeiro, Brazil. Two talkstitled: “Atom Probe Tomography of Buried Organic-Inorganic Interfaces in

Curriculum Vitae Joester 6/7Biominerals.” and “Mechanisms of Selectivity in Biomineralization of Bariumand Strontium.”Gordon Research Conference on Biomineralization, Colby Sawyer College,New London, NH. Four posters titled: “Investigating Selective Ba/SrAccumulation in Desmid Green Algae for 90 Sr Remediation.”, “BioengineeringSingle Crystal Growth.” – Presented by Ching-Hsuan Wu, “Nanoscale ChemicalTomography of Buried Organic-Inorganic Interfaces in Biominerals” –Presented by Lyle Gordon, and “In vitro stabilization of Amorphous CalciumCarbonate in Liposomes” – Presented by Chantel Tester.CECAM Workshop: Crystallization: from colloids to pharmaceuticals,Lausanne, Switzerland. Invited Talk titled: “Stabilization and Processing ofAmorphous Calcium Carbonate (ACC) Nanoparticles in Liposomes.”XRM 2010 10 th International Conference on X-Ray Microscopy, Chicago IL,USA. Poster titled: “Investigating Selectivity in Algal Biomineralization ofBarium and Strontium with X-Ray Fluorescence Microscopy.” Presented byMinna Krejci.Biological Applications of X-ray Fluorescence Microscopy, NorthwesternUniversity, Chicago, IL. Invited Talk titled: “Sequestration of Sr and Ba inDesmid Green Algae.”Gordon Research Conference on Environmental Bioinorganic Chemistry,Salve Regina University, Newport, RI. Poster titled: “Investigating SelectiveBa/Sr Accumulation in Desmid Green Algae for 90 Sr Remediation.” Presentedby: Minna Krejci.NUBOP January Meeting, Feinberg Medical School, NU, Chicago, IL.Seminar talk titled: “Imaging Buried Organic-Inorganic Interfaces inBiominerals.”ASM Chicago Chapter Meeting, Naperville, IL, USA. Invited Talk titled:“Biological Strategies in Materials Design.”2009 Materials Research Society Fall Meeting, Boston, MA, USA. Talk titled:“Atom probe tomography of buried organic-inorganic interfaces.” Presented by:Lyle Gordon.Composites at Lake Louise, Lake Louise, Alberta, Canada. Invited talk titled:“Imaging Buried Organic-Inorganic Interfaces in Biominerals.”Gordon Research Conference on Biomineralization, Colby Sawyer College,New London NH, USA. Poster titled: “In vitro stabilization of amorphouscalcium carbonate within phospholipid vesicles.” Presented by: Chantel Tester.Argonne Users Week, Argonne National Laboratory, Argonne IL, USA. Postertitled: “Investigating Selectivity in Biomineralization of Barium and Strontiumwith the X-Ray Fluorescence Microprobe.” Presented by: Minna Krejci.BioAmorPhys, The Max Planck Summer School on Amorphous Solids inPhysics and Biology, Neuhardenberg, Germany. Poster titled: “In vitrostabilization of amorphous calcium carbonate within phospholipid vesicles.”Presented by: Chantel Tester.Gordon Research Conference on Cell Biology of Metals, Salve ReginaUniversity, Newport RI, USA. Poster titled: “Selectivity in Biomineralization ofBarium and Strontium in Desmid Green Algae.” Presented by: Minna Krejci.Northwestern University, Chemical and Biological EngineeringDepartmental Seminar, Chicago IL, USA. Invited talk titled “Imaging Buried

Curriculum Vitae Joester 7/7Organic-Inorganic Interfaces in a Biological Composite Using Atom ProbeTomography”.Illinois Institute of Technology, Biophysics Departmental Seminar, ChicagoIL, USA. Invited talk titled: “Investigating Highly Hydrated Matrices In CellAdhesion and Biomineralization.2008 Gordon Research Conference on Biomineralization, Colby Sawyer College,New London NH, USA. Poster titled: “Bioengineering Single Crystal Growth.”Presented by: Ching-Hsuan Wu. Poster titled: “Selectivity in Ba 2+ and Sr 2+Transport.”Northwestern University, Biomedical Engineering Departmental Seminar,Evanston IL, USA. “Investigating Highly Hydrated Matrices In Cell Adhesionand Biomineralization”.Northwestern University, Civil and Environmental EngineeringDepartmental Seminar, Evanston IL, USA. “Investigating Highly HydratedMatrices In Cell Adhesion and Biomineralization”.2007 Northwestern University, Mechanical Engineering Departmental Seminar,Evanston IL, USA. “Investigating Highly Hydrated Matrices In Cell Adhesionand Biomineralization”.Northwestern University, Materials Science and Engineering DepartmentalSeminar, Evanston IL, USA. Talk titled “Wet Look: Investigating HighlyHydrated Matrices in Cell Adhesion and Biomineralization.”Max Planck Junior Research Groups Symposium, Munich, Germany. Talktitled “Probing the Structural Organization of Hyaluronan in the PericellularMatrix: a Combined Chemical and Biophysical Approach.”Princeton University, Chemical Engineering Departmental Seminar,Princeton NJ, USA. Talk titled “Wet Look: Investigating Highly HydratedMatrices in Cell Adhesion and Biomineralization.”72 nd Israel Chemical Society Meeting, Tel Aviv, Israel. Talk titled “Chemicaland Mechanical Probing of the Structural Organization of Hyaluronan in thePericellular Matrix.”1 st Minerva Fellows Meeting, Weizmann Institute of Science, Rehovot, Israel.Talk titled: “Wet Look: Investigating Highly Hydrated Matrices In Cell Adhesionand Biomineralization.”EPFL Lausanne Chemistry Colloquium, EPFL Lausanne, Lausanne,Switzerland. Talk titled: “wet look: hydrated matter in biological matrices in celladhesion & biomineralization.”2006 GEM 4 Summer School on Cell and Molecular Mechanics in Biomedicine,MIT, Cambridge MA, USA. Talk titled “Chemical, Biological, and PhysicalApproaches to Probing the Pericellular Coat.”Gordon Research Conference Biomineralizationn, Colby Sawyer College,New London NH, USA. Poster titled: “wet look: hydrated matter in biologicalmatrices in cell adhesion & biomineralization.”Clore Seminar on Biological Physics, Weizmann Institute of Science, Rehovot,Israel. Talk titled “Chemical, Biological, and Physical Approaches to Probingthe Pericellular Coat.”41 st EUCHEM Bürgenstock Conference on Stereochemistry, Bürgenstock,Switzerland. JSP Short Talk & Poster titled “Structure and Function ofHyaluronan in the Pericellular Matrix.”