Antimicrobial Pharmacokinetics/dynamics Bedside ... - SWAB

More documents

Recommendations

Info

How to dose in renal failure and CVVH?Creatinine clearanceRisk of overdosing in drugs with tubular excretion andunderdosing for drugs with tubular reabsorption (e.g.fuconazole)Estimations of poor qualityDose CVVH= Dose normal XCl nonrenal+Normal Dose (anuric) => Dose CVVH (ratio of normalClclearance and Cl CVVH ) CVVHCl normalAnuric Dose => adjustment using maintenance dosemultiplication factorMDMF = 11 -Fr CVVHTherapeutic Drug MonitoringBouman. Curr Opin Crit Care;14:654-659659
Pk during CVVH various antibiotics35 ml/kg*h 70 kg patientBouman. Curr Opin Crit Care;14:654-659659
Page 1 and 2: Antimicrobial Pharmacokinetics/dyna
Page 3 and 4: Inappropriate therapy and VAP morta
Page 5 and 6: Antibiotic dosing strategies in ren
Page 7 and 8: SepsisIncreased CardiacOutputLeaky
Page 9 and 10: Continuous Renal Replacement Therap
Page 11 and 12: Basic principlesExtracorporeal clea
Page 13 and 14: Efficacy and PharmacodynamicsDrug l
Page 15 and 16: Use of ciprofloxacin in the critica
Page 17 and 18: Quinolones: AUC/MIC > 125AUC above
Page 19 and 20: AUC 1-241ciprofloxacin 2 x 400 mg I
Page 21 and 22: Simulated fractional attainment of
Page 23 and 24: β-lactam static effects: streptoco
Page 25 and 26: More antibiotic specific: T > MIC f
Page 27 and 28: Randomised, prospective, open singl
Page 29 and 30: Systematic review on clinical benef
Page 31 and 32: Total costs of intravenous antibiot
Page 33: The jury is still out on continuous
Page 37 and 38: Risk of underdosingHydrophylic anti
Page 39: Thank you!Arthur van Zantenzantena@

Antimicrobial Pharmacokinetics/dynamics Bedside ... - SWAB

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?