Antimicrobial Pharmacokinetics/dynamics Bedside ... - SWAB
Antimicrobial Pharmacokinetics/dynamics Bedside ... - SWAB
Antimicrobial Pharmacokinetics/dynamics Bedside ... - SWAB
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The jury is still out on continuous infusion of beta-lactam antibiotics in critically ill patientsAdvantagesDisadvantagesLower drug acquisitioncostsReduction of work loadTDM more easyAdequate drug levels later(loading dose)Stability of the antibioticHigh MIC, all drug levelssubtherapeuticA well-designed large prospective study on potential advantages of continuousadministation of beta-lacta antibitics in ICU patients is warrantedVan Zanten ARH. Crit Care Med 2009; 37:2137-2138