Pre-Exposure Prophylaxis PrEP
Pre-Exposure Prophylaxis PrEP
Pre-Exposure Prophylaxis PrEP
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ARV Regimens for HIV nPEP<strong>Pre</strong>ferred regimenTenofovir/emtricitabine (Truvada) plus raltegravir (Isentress)Alternative regimensTenofovir/emtricitabine (Truvada) plus ritonavir-boosted atazanavir(Reyataz)Tenofovir/emtricitabine (Truvada) plus ritonavir-boosted darunavir(<strong>Pre</strong>zista)Additional possible regimensEfavirenz/tenofovir/emtricitabine (Atripla)Tenofovir/emtricitabine (Truvada) plus lopinavir/ritonavir (Kaletra)Lamivudine/zidovudine (Combivir) can be substituted for tenofovir/emtricitabine in situations in which tenofovir iscontraindicated, eg. chronic renal insufficiency.2012 United States DHHS guidelines for treatment of HIV-infected adults2012 United States DHHS guidelines for treatment of HIV infected adults.Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1infected adults and adolescents. Department of Health and Human Services. 1-239. Available athttp://www.aidsinfo.nih.gov.cuml1.md.chula.ac.th/guidelines/html/1/adult-and-adolescent-treatment-guidelines/.Accessed 28 March 2012.