Pre-Exposure Prophylaxis PrEP
Pre-Exposure Prophylaxis PrEP
Pre-Exposure Prophylaxis PrEP
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Recommended PEP RegimensBASIC REGIMENSEXPANDED REGIMENS• <strong>Pre</strong>ferred drugs- ZDV + 3TC- TDF + 3TC or• Alternative drugs- d4T + 3TC- ddI + 3TC• Basic regimens plus athird agent• PI- LPV/r - ATV/r- DRV/r - IDV/r- SQV/r - NFV or• NNRTIHIV infected source with- EFV orsuspected drug resistance or• IIbackground rate of resistancein source population > 15%- RAL orLansowitz R. NEJM 2009;361:1768.MMWR 2005;54(No. RR‐9) 1‐19.Mechai et al. J Med Virol 2008:80:9‐10Siegel et al. AIDS 2008;22:2252‐53.Eassett et al. Clin Infect Dis 2004;39:395‐401.• EI- MVCNo NVP , ABCDuration – 28 days
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