self evaluation report - Universitatea de Ştiinţe Agricole şi Medicină ...
self evaluation report - Universitatea de Ştiinţe Agricole şi Medicină ...
self evaluation report - Universitatea de Ştiinţe Agricole şi Medicină ...
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Crt. Product/patent/<br />
No. technology<br />
1 ERISOL - Antidiarrhea<br />
and rehydration oral<br />
medicine.<br />
Patent No.<br />
149003/2010, OSIM<br />
Bucuresti.<br />
2 Administration<br />
protocol (technique)<br />
of a naftalendionic<br />
<strong>de</strong>rivative used to<br />
control tumor growth.<br />
Patent granting in<br />
process; Application<br />
No.<br />
A/01250/30.11.2010.<br />
3 Naftalendionic<br />
<strong>de</strong>rivative used to<br />
control tumor growth.<br />
Patent granting in<br />
process; Application<br />
No.<br />
A/01251/30.11.2010<br />
VETERINARY MEDICINE<br />
Appendix – Technology transfer<br />
Authors Domain Beneficiary Description<br />
Roman<br />
Morar,<br />
Nicolae<br />
Miu, Emilia<br />
Morar,<br />
Corina<br />
Roman,<br />
Dana Pusta<br />
Radu<br />
Tamaian<br />
Ioan<br />
Marcus<br />
Bogdan<br />
Sevastre<br />
Iulia<br />
Prodan<br />
Niculescu<br />
Violeta<br />
Carolina<br />
Radu<br />
Tamaian<br />
Ioan<br />
Marcus<br />
Bogdan<br />
Sevastre<br />
Iulia<br />
Prodan<br />
Medicină<br />
Veterinară<br />
Veterinary<br />
oncology<br />
Veterinary<br />
oncology<br />
SC<br />
Plantarom<br />
ICSI Rm.<br />
Valcea<br />
ICSI Rm.<br />
Valcea<br />
Antidiarrhea and<br />
rehydration oral medicine<br />
The invention relates to a<br />
new 2.3-<strong>de</strong>rived<br />
naftalendionic disubstituit,<br />
chlorinated, with the<br />
formula C16H9 ClN2O3: N-<br />
(3- chloro- 1, 4- dioxo-1, 4dihidronaftalen<br />
-2-yl)<br />
pyridine-3-carboxymi<strong>de</strong>, at<br />
an injectable product, and<br />
also to its use in controlling<br />
tumor growth.<br />
The invention refers to a<br />
new <strong>de</strong>rived naphthaendionic<br />
2.3 - disubstituit,<br />
thiols, with the formula<br />
C16H10N2O3S: N-(1,4dioxo-3-sulphanilic-1,4dihidronaftalen-2-yl)<br />
pyridine-3-carboxami<strong>de</strong>, at<br />
two types of<br />
immunoconjugates<br />
(antigenic <strong>de</strong>terminants<br />
chosen as specific targets<br />
for monoclonal antibodies<br />
or for antigen binding<br />
fragments <strong>de</strong>rived from the<br />
monoclonal antibodies, are<br />
DNA topoisomerase II α<br />
chain and Tenascina C)<br />
polispecifics (with specific<br />
reactivity to Mus musculus<br />
and / or Rattus norvegicus<br />
and Homo sapiens), that<br />
have as load cytotoxic N-<br />
(1,4 - dioxo-3-sulphanilic -<br />
1,4-dihidronaftalen-2-yl)<br />
pyridine-3-carboxami<strong>de</strong>,<br />
and to the combined use of<br />
these immuno-conjugates<br />
as targeted antipro-<br />
Page 180 SELF-EVALUATION REPORT, March, 2012
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