11.07.2015 Views

Post Stroke Depression

Post Stroke Depression

Post Stroke Depression

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Biology of <strong>Post</strong> <strong>Stroke</strong> <strong>Depression</strong>•Classical anatomical associations not supported by newtechnology that allows scans etc.•Previously PSD thought to be associated with Left Anterior andLeft Basal Ganglia lesions•Situation complicated by related conditions such as FrontalLobe Apathy and Emotional Lability (Supra Nuclear Palsy etc.)•Current work on the “multifactorial” nature of <strong>Post</strong> <strong>Stroke</strong><strong>Depression</strong>, integrating anatomical lesions with interruptedprojection pathways and subsequent alterations inneurotransmitters.

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