Post Stroke Depression

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Results• Superior in efficacy:• Mirtazapine, escitalopram, venlafaxine, sertraline• Superior in acceptability:• Escitalopram, sertraline, bupropion, citalopram• Authors conclude:• “Clinically important differences exist betweenantidepressants”• “Both efficacy and safety in favour of escitalopram andsertraline”Cipriani et al., Lancet 2009; 373: 746-58
Efficacy Acceptability• Mirtazepine• Escitalopram• Venlafaxine• Sertraline• Citalopram• Bupropion• Paroxetine• Fluoxetine• Duloxetine• Fluvoxamine(Omits drugs not available in Canada)• Sertraline• Escitalopram• Bupropion• Citalopram• Fluoxetine• Mirtazepine• Venlafaxine• Paroxetine• Fluvoxamine• Duloxetine(ditto)
Page 2 and 3: Disclosure of Potential for Conflic
Page 4: Post-Stroke Depression Epidemiology
Page 7 and 8: Depression in Medical illness:The (
Page 9 and 10: PDQ-9 -Example
Page 11 and 12: EMPIRICAL STUDIES•There are many
Page 13 and 14: …but there are positive studies
Page 15 and 16: Recommended ReviewWilliam Feinberg
Page 17 and 18: Results of a Pool of Studies Assess
Page 19 and 20: Are there stroke-specific factors?
Page 21 and 22: Escitalopram and post-stroke cognit
Page 23 and 24: STAR*D SequencedTreatment Alternati
Page 25: The Lancet 2009: Cipriani et al.Bac

Post Stroke Depression

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