Post Stroke Depression

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Comparative efficacy and acceptability of12 new-generation antidepressants:a multiple-treatments meta-analysisCipriani A, et al.Lancet , February 2009
The Lancet 2009: Cipriani et al.Background• Independently funded meta-analysis that compared theefficacy and patient acceptability of 12 antidepressants• 117 randomised clinical trials (25 928 participants) from1991 - 30 th Nov. 2007• Included 12 new-generation anti-depressants:bupropion, citalopram, duloxetine, escitalopram, fluoxetine,fluvoxamine, milnacipran, mirtazapine, paroxetine, reboxetine,sertraline and venlafaxine• Assessed the acute treatment phase (first 8 weeks oftreatment) in adults with unipolar major depressive disorderCipriani et al., Lancet 2009; 373: 746-58
Page 2 and 3: Disclosure of Potential for Conflic
Page 4: Post-Stroke Depression Epidemiology
Page 7 and 8: Depression in Medical illness:The (
Page 9 and 10: PDQ-9 -Example
Page 11 and 12: EMPIRICAL STUDIES•There are many
Page 13 and 14: …but there are positive studies
Page 15 and 16: Recommended ReviewWilliam Feinberg
Page 17 and 18: Results of a Pool of Studies Assess
Page 19 and 20: Are there stroke-specific factors?
Page 21 and 22: Escitalopram and post-stroke cognit
Page 23: STAR*D SequencedTreatment Alternati
Page 27: Efficacy Acceptability• Mirtazepi

Post Stroke Depression

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