Sircol Publications - Tebu-Bio
Sircol Publications - Tebu-Bio
Sircol Publications - Tebu-Bio
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2009<br />
Allograft Collagen<br />
<strong>Sircol</strong> Assay Citations in Scientific Literature<br />
Abreu,E.L., Palmer,M.P. and Murray,M.M. (2009) Storage conditions do not have detrimental effect on allograft<br />
collagen or scaffold performance. Cell and Tissue Banking, 10, 333-340.<br />
Murine Colon<br />
Alexandra,M., Arthur,W., Van,P. and Derek,M. (2009) Infection with Hymenolepis diminuta Is More Effective than Daily<br />
Corticosteroids in Blocking Chemically Induced Colitis in Mice. Journal of <strong>Bio</strong>medicine and <strong>Bio</strong>technology, doi:<br />
10.1155/2010/384523.<br />
MC3T3-E1 Pre-Osteoblasts<br />
Alford,A.I., Terkhorn,S.P., Reddy,A.B. and Hankenson,K.D. (2009) Thrombospondin-2 regulates matrix mineralization in<br />
MC3T3-E1 pre-osteoblasts. Bone, doi: 10.1016/j.bone.2009.08.058.<br />
Fibroblast Cells<br />
Aramwit,P., Kanokpanont,S., De-Eknamkul,W., Kamei,K. and Srichana,T. (2009) The Effect of Sericin with Variable<br />
Amino-Acid Content from Different Silk Strains on the Production of Collagen and Nitric Oxide. Journal of<br />
<strong>Bio</strong>materials Science, Polymer Edition, 20, 1295-1306.<br />
Fibroblast Populated Fibrin Gels<br />
Balestrini,J.L. and Billiar,K.L. (2009) Magnitude and Duration of Stretch Modulate Fibroblast Remodeling. Journal of<br />
<strong>Bio</strong>mechanical Engineering, 131, 051005.<br />
Osteoblasts<br />
Ball,M.D., O’Connor,D. and Pandit,A. (2009) Use of tissue transglutaminase and fibronectin to influence osteoblast<br />
responses to tricalcium phosphate scaffolds. Journal of Materials Science: Materials in Medicine, 20, 113-122.<br />
Murine Lung Tissue<br />
Banerjee,E.R., Jiang,Y., Henderson,W.R., Latchman,Y. and Papayannopoulou,T. (2009) Absence of α4 but not ß2<br />
integrins restrains development of chronic allergic asthma using mouse genetic models. Experimental<br />
Hematology, 37, 715-727.<br />
Murine Renal Tissue and a Proximal Tubule Epithelial Cell Line (HK-2 Cells)<br />
Bani-Hani,A.H., Leslie,J.A., Asanuma,H., Dinarello,C.A., Campbell,M.T., Meldrum,D.R., Zhang,H., Hile,K. and<br />
Meldrum,K.K. (2009) IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition<br />
and renal fibrosis. Kidney International, 76, 500-511.<br />
Human Fibroblasts<br />
Bendersky,A., Markovits,N. and Bank,I. (2009) Vγ9+ γδT cells in systemic sclerosis patients are numerically and<br />
functionally preserved and induce fibroblast apoptosis. Immunobiology, doi: 10.1016/j.imbio.2009.05.012.<br />
Mesenchymal Stem Cells on Chitosan Scaffold<br />
Breyner, N.M., Hell, R.C.R., Carvalho, L.R.P., Machado, C.B., Peixoto Filho, I.N., Valério, P., Pereira, M.M.<br />
and Goes, A.M. (2009) Effect of a Three-Dimensional Chitosan Porous Scaffold on the Differentiation<br />
of Mesenchymal Stem Cells into Chondrocytes. Cells Tissues Organs, doi: 10.1159/000231472.
NIH 3T3 Fibroblasts<br />
Chen,M., Michaud,H. and Bhowmick,S. (2009) Controlled Vacuum Seeding as a Means of Generating Uniform Cellular<br />
Distribution in Electrospun Polycaprolactone (PCL) Scaffolds. Journal of <strong>Bio</strong>mechanical Engineering, 131,<br />
074521.<br />
Human Fibroblasts<br />
Choi,H., Kim,D., Kim,J.W., Ngadiran,S., Sarmidi,M.R. and Park,C.S. (2009) Labisia pumila extract protects skin cells<br />
from photoaging caused by UVB irradiation. Journal of <strong>Bio</strong>science and <strong>Bio</strong>engineering, doi:<br />
10.1016/j.biosc.2009.08.478.<br />
Rat Dorsal Tissue<br />
Chung,P.S., Shin,J.I., Chang,S.Y. and Ahn,J.C. (2009) Histological Change and Collagen Formation on Laser Wounded<br />
Rat using 808 Diode Laser and CO2 Laser. Science for the Life of Issue 1, 15, 81-86.<br />
Murine Lung Tissue<br />
Couillin,I., Vasseur,V., Charron,S., Gasse,P., Tavernier,M., Guillet,J., Lagente,V., Fick,L., Jacobs,M. and Coelho,F.R.<br />
(2009) IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema. The Journal<br />
of Immunology, 183, 8195.<br />
Human Mucosal Myofibroblasts<br />
Di Sabatino,A., Jackson,C.L., Pickard,K.M., Buckley,M., Rovedatti,L., Leakey,N.A.B., Picariello,L., Cazzola,P.,<br />
Monteleone,G. and Tonelli,F. (2009) Transforming growth factor ß signalling and matrix metalloproteinases in<br />
the mucosa overlying Crohn's disease strictures. British Medical Journal, 58, 777-789.<br />
Murine Lung Tissue<br />
Du,G., Jin,L., Han,X., Song,Z., Zhang,H. and Liang,W. (2009) Naringenin: A Potential Immunomodulator for Inhibiting<br />
Lung Fibrosis and Metastasis. Cancer Research, 69, 3205.<br />
Porcine Bone Marrow-Derived Mesenchymal Cells (bMSCs)<br />
Elder,S.H., Cooley Jr,A.J., Borazjani,A., Sowell,B.L., To,H. and Tran,S.C. (2009) Production of Hyaline-like Cartilage by<br />
Bone Marrow Mesenchymal Stem Cells in a Self-Assembly Model. Tissue Engineering Part A, 15, 3025 – 3036.<br />
Murine Lung Tissue<br />
Failla,M., Genovese,T., Mazzon,E., Fruciano,M., Fagone,E., Gili,E., Barera,A., La Rosa,C., Conte,E. and Crimi,N. (2009)<br />
16, 16-Dimethyl Prostaglandin E2 Efficacy on Prevention and Protection from Bleomycin-Induced Lung Injury<br />
and Fibrosis. American Journal of Respiratory Cell and Molecular <strong>Bio</strong>logy, 41, 50 – 58.<br />
Skeletal Muscle Construct from C2C12 Myoblast Cell Line<br />
Fujita,H., Shimizu,K. and Nagamori,E. (2009) Novel method for fabrication of skeletal muscle construct from the C2C12<br />
myoblast cell line using serum-free medium AIM-V. <strong>Bio</strong>technology and <strong>Bio</strong>engineering, 103, 1034-1041.<br />
Murine Lung Tissue<br />
Fukumoto,J., Harada,C., Kawaguchi,T., Suetugu,S., Maeyama,T., Inoshima,I., Hamada,N., Kuwano,K. and Nakanishi,Y.<br />
(2009) Amphiregulin attenuates bleomycin-induced pneumopathy in mice. American Journal of Physiology-<br />
Lung Cellular and Molecular Physiology, doi: 10.1152/ajplung.90576.2008.<br />
Murine Lung Tissue<br />
Gill,S.E., Huizar,I., Bench,E.M., Sussman,S.W., Wang,Y., Khokha,R. and Parks,W.C. (2010) Tissue Inhibitor of<br />
Metalloproteinases 3 Regulates Resolution of Inflammation following Acute Lung Injury. American Journal of<br />
Pathology, 176, 64-73.
Murine Lung Tissue<br />
Glass,W.G., Argentieri,R.L., Bracht,M., Farrell,F.X., Das,A.M., Del Vecchio,A.M., Hogaboam,C.M. and Murray,L.A.<br />
(2009) Generation of bleomycin-induced lung fibrosis is independent of IL-16. Cytokine, 46, 17–23.<br />
Atherosclerotic Carotid Plaques<br />
Gonçalves,I., Stollenwerk,M.M., Lindholm,M.W., Dias,N., Pedro,L.M., Fernandes,J.F., Moses,J., Fredrikson,G.N.,<br />
Nilsson,J. and Ares,M.P.S. (2009) Activator protein-1 in carotid plaques is related to cerebrovascular symptoms<br />
and cholesteryl ester content. Cardiovascular Pathology, doi: 10.1016/j.carpath.2009.09.003.<br />
Human Bone Marrow Stromal Cells<br />
Green,D.W., Bolland,B.J.R.F., Kanczler,J.M., Lanham,S.A., Walsh,D., Mann,S. and Oreffo,R.O.C. (2009) Augmentation<br />
of skeletal tissue formation in impaction bone grafting using vaterite microsphere biocomposites. <strong>Bio</strong>materials,<br />
30, 1918-1927.<br />
Murine Colon Tissue<br />
Guan,Q., Ma,Y., Hillman,C.L., Ma,A., Zhou,G., Qing,G. and Peng,Z. (2009) Development of recombinant vaccines<br />
against IL-12/IL-23 p40 and in vivo evaluation of their effects in the downregulation of intestinal inflammation<br />
in murine colitis. Vaccine, 27, 7096 – 7104.<br />
Articular Cartilages from Human Knee Joint<br />
Han,D.W., Bae,J.Y. and Hyon,S.H. (2009) <strong>Bio</strong>chemical and Histological Evaluations of Articular Cartilages Preserved in<br />
Cold Storage Solution Containing Green Tea Catechin, EGCG. Tissue Engineering and Regenerative Medicine, 6,<br />
380-387.<br />
Murine Asthma Model<br />
Hansen,G. (2009) Different role of CD30 in the development of acute and chronic airway inflammation in a murine<br />
asthma model. Eur.J.Immunol, 39, 1736-1742.<br />
Bladder Smooth Muscle Cells<br />
Heise,R.L., Ivanova,J., Parekh,A. and Sacks,M.S. (2009) Generating Elastin-Rich Small Intestinal Submucosa-Based<br />
Smooth Muscle Constructs Utilizing Exogenous Growth Factors and Cyclic Mechanical Stimulation. Tissue<br />
Engineering Part A, 15, 3951-3960.<br />
Rat Renal Tissue<br />
He,L., Qi,Y., Rong,X., Jiang,J., Yang,Q., Yamahara,J., Murray,M. and Li,Y. (2009) The Ayurvedic medicine Salacia<br />
oblonga attenuates diabetic renal fibrosis in rats: suppression of angiotensin II/AT1 signaling. Evidence-based<br />
Complementary and Alternative Medicine, doi: 10.1093/ecam/nep095.<br />
Murine Lung Mesenchymal Cells and Myofibroblasts<br />
Hecker,L., Vittal,R., Jones,T., Jagirdar,R., Luckhardt,T.R., Horowitz,J.C., Pennathur,S., Martinez,F.J. and<br />
Thannickal,V.J. (2009) NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung<br />
injury. Nature Medicine, 15, 1077-1081.<br />
Human Skin Fibroblasts<br />
Hemmatazad,H., Rodrigues,H.M., Maurer,B., Brentano,F., Pileckyte,M., Distler,J.H.W., Gay,R.E., Michel,B.A., Gay,S.<br />
and Huber,L.C. (2009) Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic<br />
sclerosis. Arthritis & Rheumatism, 60, 1519-1529.
Rabbit Subcutaneous Implant Model<br />
Henry,J.A., Burugapalli,K., Neuenschwander,P. and Pandit,A. (2009) Structural variants of biodegradable<br />
polyesterurethane in vivo evoke a cellular and angiogenic response that is dictated by architecture. Acta<br />
<strong>Bio</strong>materialia, 5, 29-42.<br />
Rat Cardiac Fibroblasts<br />
Hermida,N., Lopez,B., Gonzalez,A., Dotor,J., Lasarte,J.J., Sarobe,P., Borras-Cuesta,F. and Diez,J. (2009) A synthetic<br />
peptide from transforming growth factor-β 1 type III receptor prevents myocardial fibrosis in spontaneously<br />
hypertensive rats. Cardiovascular Research, 81, 601.<br />
Murine Embryonic Fibroblasts and Primary Hepatocytes<br />
Hosui,A., Kimura,A., Yamaji,D., Zhu,B., Na,R. and Hennighausen,L. (2009) Loss of STAT5 causes liver fibrosis and<br />
cancer development through increased TGF-ß and STAT3 activation. Journal of Experimental Medicine,<br />
doi:10.1084/jem.20080003.<br />
Human Osteoarthritis Cartilage explants and a Rabbit Model of Osteoarthritis<br />
Huh,J.E., Baek,Y.H., Ryu,S.R., Lee,J.D., Choi,D.Y. and Park,D.S. (2009) Efficacy and mechanism of action of KHBJ-9B,<br />
a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model<br />
of collagenase-induced osteoarthritis. International Immunopharmacology, 9, 230-240.<br />
Mouse Osteoclasts<br />
Idris,A.I., Greig,I.R., Bassonga-Landao,E., Ralston,S.H. and van't Hof,R.J. (2009) Identification of Novel Biphenyl<br />
Carboxylic Acid Derivatives as Novel Antiresorptive Agents that Do Not Impair Parathyroid Hormone-Induced<br />
Bone Formation. Endocrinology, 150, 5-13.<br />
Human Term Fetal Membranes<br />
Jabareen,M., Mallik,A.S., Bilic,G., Zisch,A.H. and Mazza,E. (2009) Relation between mechanical properties and<br />
microstructure of human fetal membranes: An attempt towards a quantitative analysis. European Journal of<br />
Obstetrics and Gynecology, 144, 134-141.<br />
Murine Lung Tissue<br />
Kakizaki,T., Kohno,M., Watanabe,M., Tajima,A., Izumi,Y., Miyasho,T., Tasaka,S., Fukunaga,K., Maruyama,I. and<br />
Ishizaka,A. (2009) Exacerbation of Bleomycin-Induced Injury and Fibrosis by Pneumonectomy in the Residual<br />
Lung of Mice. Journal of Surgical Research, 154, 336-344.<br />
Murine Lung Tissue<br />
Kanda,A., Driss,V., Hornez,N., Abdallah,M., Roumier,T., Abboud,G., Legrand,F., Staumont-Sallé�D., Quéant,S. and<br />
Bertout,J. (2009) Eosinophil-derived IFN- induces airway hyperresponsiveness and lung inflammation in the<br />
absence of lymphocytes. The Journal of Allergy and Clinical Immunology, 124, 573-582.<br />
Rat Renal Tissue and Cultured Mesangial Cells<br />
Kang,Y.S., Ko,G.J., Lee,M.H., Song,H.K., Han,S.Y., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2009) Effect of<br />
eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats.<br />
Nephrology Dialysis Transplantation, 24, 73-84.<br />
Murine Skin Tissue<br />
Kanno,Y., Kawashita,E., Minamida,M., Kaneiwa,A., Okada,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2009) α2-<br />
Antiplasmin Is Associated with the Progression of Fibrosis. American Journal of Pathology, doi:<br />
10.2353/ajpath.2010.090150.
Human Dermal Fibroblasts<br />
Kim,H.J., Song,S.B., Lee,J.Y., Cho,B.K., Cho,D.H. and Park,H.J. (2009) Interleukin-18 Downregulates Collagen<br />
Production in Human Dermal Fibroblasts via ERK pathway. The Journal of Immunology, 182, 98-14.<br />
Rat Ear Fibroblast Cells<br />
Kim, J.-H. and Choi, J.-Y. (2009) Study on thermosensitivity of chitosan scaffold and on its effects on fibroblast<br />
proliferation in cell therapy for soft tissue augmentation. J. Kor. Oral Maxillofac. Surg., 35, 146-152.<br />
Rat Common Bile Duct Fibroblasts<br />
Kim,T.H., Moon,J.H., Savard,C.E., Kuver,R. and Lee,S.P. (2009) Effects of lipopolysaccharide on platelet-derived<br />
growth factor isoform and receptor expression in cultured rat common bile duct fibroblasts and cholangiocytes.<br />
Journal of Gastroenterology and Hepatology, 24, 1218-1225.<br />
Osteoblastic MC3T3-E1 Cells<br />
Kim,Y.H. and Choi,E.M. (2009) Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric<br />
oxide in MC3T3-E1 cells by pomegranate ethanol extract. Phytotherapy Research, 23, 737-739.<br />
Immobilised Matrix Vesicle Model<br />
Kinugawa,M., Fukuzawa,S. and Tachibana,K. (2009) Skeletal protein protection: the mode of action of an antiosteoporotic<br />
marine alkaloid, norzoanthamine. Journal of Bone and Mineral Metabolism, 27, 303-314.<br />
Mouse and Human Lung Fibroblasts<br />
Königshoff,M., Kramer,M., Balsara,N., Wilhelm,J., Amarie,O.V., Jahn,A., Rose,F., Fink,L., Seeger,W. and Schaefer,L.<br />
(2009) WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans<br />
with idiopathic pulmonary fibrosis. The Journal of Clinical Investigation, 119, 772-787.<br />
Murine Bone Marrow Mesenchymal Stem Cells<br />
Kumamoto,M., Nishiwaki,T., Matsuo,N., Kimura,H. and Matsushima,K. (2009) Minimally-cultured Bone Marrow<br />
mesenchymal stem cells ameliorate fibrotic lung injury. European Respiratory Journal, doi:10.1183/<br />
09031936-00128508.<br />
Mouse Breast Cell Line<br />
Lee,C.G., Hartl,D., Lee,G.R., Koller,B., Matsuura,H., Da Silva,C.A., Sohn,M.H., Cohn,L., Homer,R.J. and Kozhich,A.A.<br />
(2009) Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue<br />
responses and apoptosis. Journal of Experimental Medicine, 206, 1149-1166.<br />
Chondrocytes<br />
Lee,N.K., Oh,H.J., Hong,C.M., Suh,H. and Hong,S.H. (2009) Comparison of the synthetic biodegradable polymers,<br />
polylactide (PLA), and polylactic-co-glycolic acid (PLGA) as scaffolds for artificial cartilage. <strong>Bio</strong>technology and<br />
<strong>Bio</strong>process Engineering, 14, 180-186.<br />
Murine Lung Tissue<br />
Lee,J., Reddy,R., Barsky,L., Scholes,J., Chen,H., Shi,W. and Driscoll,B. (2009) Lung alveolar integrity is compromised<br />
by telomere shortening in telomerase-null mice. American Journal of Physiology- Lung Cellular and Molecular<br />
Physiology, 296, L57.<br />
Human Dermal Fibroblasts<br />
Lefler,A. and Ghanem,A. (2009) Development of bFGF-Chitosan Matrices and Their Interactions with Human Dermal<br />
Fibroblast Cells. Journal of <strong>Bio</strong>materials Science, Polymer Edition, 20, 1335-1351.
Connective Tissue and Fibroblasts<br />
Lin,Y.K. and Kuan,C.Y. (2009) Development of 4-hydroxyproline analysis kit and its application to collagen<br />
quantification. Food Chemistry, doi: 10.1016/j.foodchem.2009.08.009.<br />
Rat Hepatic Stellate Cells<br />
Lin,Y.L., Lin,C.Y., Chi,C.W. and Huang,Y.T. (2009) Study on antifibrotic effects of curcumin in rat hepatic stellate<br />
cells. Phytotherapy Research, 23, 927-932.<br />
Rat Hepatic Stellate Cell Line (HSC-T6)<br />
Lin,Y.L., Wu,C.F. and Huang,Y.T. (2009) Effects of rhubarb on migration of rat hepatic stellate cells. Journal of<br />
Gastroenterology and Hepatology, 24, 453-461.<br />
Human Myocardium<br />
Lopez,B., Querejeta,R., Gonzalez,A., Beaumont,J., Larman,M. and Diez,J. (2009) Impact of Treatment on Myocardial<br />
Lysyl Oxidase Expression and Collagen Cross-Linking in Patients With Heart Failure. Hypertension, 53, 236-242.<br />
Osteoblastic Cell Cultures<br />
Lozano,D., Manzano,M., Doadrio,J.C., Salinas,A.J., Vallet-Regí�M., Gómez-Barrena,E. and Esbrit,P. (2009) Osteostatinloaded<br />
bioceramics stimulate osteoblastic growth and differentiation. Acta <strong>Bio</strong>materialia, doi:<br />
10.1016/j.actbio.2009.08.033.<br />
Bone Marrow Cultures and Osteoblastic MC3T3-E1 Cells<br />
Lozano,D., de Castro,L.F., Dapía,S., Andrade-Zapata,I., Manzarbeitia,F., Ayvarez-Arroyo,M., Gómez-Barrena,E. and<br />
Esbrit,P. (2009) Role of Parathyroid Hormone-Related Protein in the Decreased Osteoblast Function in<br />
Diabetes-Related Osteopenia. Endocrinology, 150, 2027-2035.<br />
Murine Lung Tissue<br />
Manicone,A.M., Huizar,I. and McGuire,J.K. (2009) Matrilysin (Matrix Metalloproteinase-7) Regulates Anti-Inflammatory<br />
and Antifibrotic Pulmonary Dendritic Cells That Express CD103 αE ß7-Integrin). American Journal of Pathology,<br />
175, 2319 – 2331.<br />
Murine Lung Tissue<br />
Markart,P., Luboeinski,T., Korfei,M., Schmidt,R., Wygrecka,M., Mahavadi,P., Mayer,K., Wilhelm,J., Seeger,W. and<br />
Guenther,A. (2009) Alveolar Oxidative Stress is Associated with Elevated Levels of Nonenzymatic Low-<br />
Molecular-Weight Antioxidants in Patients with Different Forms of Chronic Fibrosing Interstitial Lung Diseases.<br />
Antioxidants & Redox Signaling, 11, 227-240.<br />
Human Fibrocytes<br />
Mehrad,B., Burdick,M.D. and Strieter,R.M. (2009) Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary<br />
fibrosis. International Journal of <strong>Bio</strong>chemistry and Cell <strong>Bio</strong>logy, 41, 1708-1718.<br />
Human Retinal Pigment (ARPE-19) Cell Line<br />
Morales,S.A., Mareninov,S., Wadehra,M., Zhang,L., Goodglick,L., Braun,J. and Gordon,L.K. (2009) FAK Activation and<br />
the Role of Epithelial Membrane Protein 2 (EMP2) in Collagen Gel Contraction. Investigative Ophthalmology &<br />
Visual Science, 50, 462-469.
EpiDerm FT Engineered Skin, Murine Epidermal Cells (JB6 P+) and Immune-Competent Hairless SKH-1 Mice<br />
Murray,A.R., Kisin,E., Leonard,S.S., Young,S.H., Kommineni,C., Kagan,V.E., Castranova,V. and Shvedova,A.A. (2009)<br />
Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology,<br />
257, 161-171.<br />
Murine Peritoneal Fibroblasts<br />
Nakav,S., Kachko,L., Vorobiov,M., Rogachev,B., Chaimovitz,C., Zlotnik,M. and Douvdevani,A. (2009) Blocking<br />
adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models. Nephrology<br />
Dialysis Transplantation, doi:10.1093/ndt/gfp041.<br />
Bovine Chondrocytes Seeded in Non-Adherent Agarose Molds<br />
Natoli,R.M., Revell,C.M. and Athanasiou,K.A. (2009) Chondroitinase ABC Treatment Results in Increased Tensile<br />
Properties of Self-Assembled Tissue Engineered Articular Cartilage. Tissue Engineering.Part A, 15, 3119 – 3128.<br />
Murine Lung Tissue<br />
Nicola,T., Hagood,J.S., James,M.L., MacEwen,M.W., Williams,T.A., Hewitt,M.M., Schwiebert,L., Bulger,A., Oparil,S.<br />
and Chen,Y.F. (2009) Loss of Thy-1 inhibits alveolar development in the newborn mouse lung. American<br />
Journal of Physiology- Lung Cellular and Molecular Physiology, 296, L738-L750.<br />
Murine Lung Tissue<br />
Niese,K.A., Collier,A.R., Hajek,A.R., Cederbaum,S.D., O'Brien,W.E., Wills-Karp,M., Rothenberg,M.E. and<br />
Zimmermann,N. (2009) Bone marrow cell derived arginase I is the major source of allergen-induced lung<br />
arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in<br />
mice. BMC Immunology, 10, 33.<br />
Murine Lung Fibroblasts<br />
Oga,T., Matsuoka,T., Yao,C., Nonomura,K., Kitaoka,S., Sakata,D., Kita,Y., Tanizawa,K., Taguchi,Y. and Chin,K. (2009)<br />
Prostaglandin F2 αreceptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of<br />
transforming growth factor-ß. Nature medicine, 15, 1426-1430.<br />
Human Lung Fibroblasts<br />
Okada,M., Suzuki,K., Matsumoto,M., Takada,K., Nakanishi,T., Horikoshi,H., Higuchi,T., Hosono,Y., Nakayama,M. and<br />
Ohsuzu,F. (2009) Effects of angiotensin on the expression of fibrosis-associated cytokines, growth factors, and<br />
matrix proteins in human lung fibroblasts. Journal of Clinical Pharmacy & Therapeutics, 34, 289-299.<br />
Rat Calvariae Osteoblasts<br />
Orriss,I.R., Key,M.L., Colston,K.W. and Arnett,T.R. (2009) Inhibition of osteoblast function in vitro by<br />
aminobisphosphonates. Journal of Cellular <strong>Bio</strong>chemistry, 106, 109-118.<br />
Swiss Mouse Intraplantar Region<br />
Pareja-Santos,A., Saraiva,T.C., Costa,E.P., Santos,M.F., Zorn,T.T., Souza,V.M.O., Lopes-Ferreira,M. and Lima,C. (2009)<br />
Delayed local inflammatory response induced by Thalassophryne nattereri venom is related to extracellular<br />
matrix degradation. International Journal of Experimental Pathology, 90, 34-43.<br />
Human Dermal Fibroblasts<br />
Park,H.J., Cho,D.H., Kim,H.J., Lee,J.Y., Cho,B.K., Bang,S.I., Song,S.Y., Yamasaki,K., Di Nardo,A. and Gallo,R.L. (2009)<br />
Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37. The Journal<br />
of investigative dermatology, 129, 843-850.
Rat Respiratory Tract<br />
Pauluhn,J. (2009) Subchronic 13-week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects are<br />
determined by Density of Agglomerate Structures, not fibrillar Structures. Toxicological Sciences, doi:<br />
10.1093/toxsci/kfp247.<br />
Tissue Engineered Valve Constructs Seeded With Mesenchymal Stem Cells<br />
Ramaswamy,S., Gottlieb,D., Engelmayr,G.C., Aikawa,E., Schmidt,D.E., Gaitan-Leon,D.M., Sales,V.L., Mayer,J.E. and<br />
Sacks,M.S. (2010) The role of organ level conditioning on the promotion of engineered heart valve tissue<br />
development in-vitro using mesenchymal stem cells. <strong>Bio</strong>materials, 31, 1114-1125.<br />
Murine Lung Tissue<br />
Ryman-Rasmussen,J.P., Tewksbury,E.W., Moss,O.R., Cesta,M.F., Wong,B.A. and Bonner,J.C. (2009) Inhaled multiwalled<br />
carbon nanotubes potentiate airway fibrosis in murine allergic asthma. American Journal of Respiratory Cell<br />
and Molecular <strong>Bio</strong>logy, 40, 349-358.<br />
Dermal Fibroblasts<br />
Saesoo,S., Sramala,I., Soottitantawat,A., Charinpanitkul,T. and Ruktanonchai,U.R. (2009) Enhanced stability and in<br />
vitro bioactivity of surfactant-loaded liposomes containing Asiatic Pennywort extract. Journal of<br />
Microencapsulation, doi: 10.3109/02652040903447686.<br />
Ovine Peripheral Blood Endothelial Progenitor Cells<br />
Sales,V.L., Mettler,B.A., Engelmayr Jr,G.C., Aikawa,E., Bischoff,J., Martin,D.P., Exarhopoulos,A., Moses,M.A.,<br />
Schoen,F.J. and Sacks,M.S. (2009) Endothelial Progenitor Cells as a Sole Source for Ex Vivo Seeding of Tissue-<br />
Engineered Heart Valves. Tissue Engineering Part A, doi: 10.1089/ten.tea.2009.0424.<br />
Human Heart Valves<br />
Schenke-Layland,K., Stock,U.A., Nsair,A., Xie,J., Angelis,E., Fonseca,C.G., Larbig,R., Mahajan,A., Shivkumar,K.,<br />
Fishbein,M.C. and MacLellan, W.R. (2009) Cardiomyopathy is associated with structural remodelling of heart<br />
valve extracellular matrix. European Heart Journal, 30, 2254-2265.<br />
Human Foreskin Fibroblasts<br />
Schenke-Layland,K., Rofail,F., Heydarkhan,S., Gluck,J.M., Ingle,N.P., Angelis,E., Choi,C.H., MacLellan,W.R.,<br />
Beygui,R.E. and Shemin,R.J. (2009) The use of three-dimensional nanostructures to instruct cells to produce<br />
extracellular matrix for regenerative medicine strategies. <strong>Bio</strong>materials, 30, 4665-4675.<br />
Mesenchymal Stem Cells<br />
Schnabel,L.V., Lynch,M.E., van der Meulen,M.C.H., Yeager,A.E., Kornatowski,M.A. and Nixon,A.J. (2009) Mesenchymal<br />
stem cells and insulin-like growth factor-I gene-enhanced mesenchymal stem cells improve structural aspects<br />
of healing in equine flexor digitorum superficialis tendons. Journal of Orthopaedic Research, 27, 1392-1398.<br />
Murine Airways<br />
Schneider,D.J., Lindsay,J.C., Zhou,Y., Molina,J.G. and Blackburn,M.R. (2009) Adenosine and osteopontin contribute to<br />
the development of chronic obstructive pulmonary disease. The FASEB Journal, doi: 10.1096/fj.09-140772.<br />
Anterior Cruciatge Ligament Cell and T-Lymophocytes on Composite Silk Scaffolds<br />
Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S. and Park,J.K. (2009) Increase in cell migration and<br />
angiogenesis in a composite silk scaffold for tissue-engineered ligaments. Journal of Orthopaedic Research,<br />
27, 495-503.
Murine Skin and Lung Tissue<br />
Servettaz,A., Goulvestre,C., Kavian,N., Nicco,C., Guilpain,P., Chereau,C., Vuiblet,V., Guillevin,L., Mouthon,L. and<br />
Weill,B. (2009) Selective Oxidation of DNA Topoisomerase 1 Induces Systemic Sclerosis in the Mouse. The<br />
Journal of Immunology, 182, 5855-5864.<br />
Murine Conjunctival Tissue<br />
Shii,D., Nakagawa,S., Shinomiya,K., Yoshimi,M., Katsuta,O., Oda,T. and Nakamura,M. (2009) Cyclosporin A Eye Drops<br />
Inhibit Fibrosis and Inflammatory Cell Infiltration in Murine Type I Allergic Conjunctivitis without Affecting the<br />
Early-Phase Reaction. Current Eye Research, 34, 426-437.<br />
Smooth Muscle Cells<br />
Shin,J.W., Lee,Y.J., Heo,S.J., Park,S.A., Kim,S.H., Kim,Y.J., Kim,D.H. and Shin,J.W. (2009) Manufacturing of Multi-<br />
Layered Nanofibrous Structures Composed of Polyurethane and Poly (ethylene oxide) as Potential Blood Vessel<br />
Scaffolds. Journal of <strong>Bio</strong>materials Science, Polymer Edition, 20, 5, 757-771.<br />
Rat Myogenic Cells from Large Thigh Muscle<br />
Stern,M.M., Myers,R.L., Hammam,N., Stern,K.A., Eberli,D., Kritchevsky,S.B., Soker,S. and Van Dyke,M. (2009) The<br />
influence of extracellular matrix derived from skeletal muscle tissue on the proliferation and differentiation of<br />
myogenic progenitor cells ex vivo. <strong>Bio</strong>materials, 30, 2393-2399.<br />
Mesenchymal Progenitor Cells (Fibrocytes)<br />
Strieter,R.M., Keeley,E.C., Hughes,M.A., Burdick,M.D. and Mehrad,B. (2009) The role of circulating mesenchymal<br />
progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. Journal of leukocyte biology, 86, 1111-<br />
1118.<br />
Mouse Osteoblastic Cell Line (MC3T3-E1)<br />
Suh,K.S., Choi,E.M., Kwon,M., Chon,S., Oh,S., Woo,J.T., Kim,S.W., Kim,J.W. and Kim,Y.S. (2009) Kaempferol<br />
Attenuates 2-Deoxy-D-ribose-Induced Oxidative Cell Damage in MC3T3-E1 Osteoblastic Cells. <strong>Bio</strong>logical &<br />
Pharmaceutical Bulletin, 32, 746-749.<br />
Rat Pancreatic Tissue<br />
Suzuki,N., Masamune,A., Kikuta,K., Watanabe,T., Satoh,K. and Shimosegawa,T. (2009) Ellagic Acid Inhibits Pancreatic<br />
Fibrosis in Male Wistar Bonn/Kobori Rats. Digestive Diseases and Sciences, 54, 802-810.<br />
Murine Patellar Tendons<br />
Szczodry,M., Zhang,J., Lim,C., Davitt,H.L., Yeager,T., Fu,F.H. and Wang,J.H.C. (2009) Treadmill running exercise<br />
results in the presence of numerous myofibroblasts in mouse patellar tendons. Journal of Orthopaedic<br />
Research, 27, 1373-1378.<br />
Human Embryonic Stem Cells (hESCs)<br />
Toh,W.S., Guo,X-M., Choo,A.B., Lu,K., Lee,E.H. and Cao,T. (2009) Differentiation and Enrichment of Expandable<br />
Chondrogenic Cells from Human Embryonic Stem Cells in Vitro. Journal of Cellular and Molecular Medicine,<br />
doi:10.1111/j.1582-4934.2009.00762.x.<br />
Murine Hepatic Tissue<br />
Tong,Z.Y., Chen,R., Alt,D.S., Kemper,S., Perbal,B. and Brigstock,D.R. (2009) Susceptibility to liver fibrosis in mice<br />
expressing a connective tissue growth factor transgene in hepatocytes. Hepatology, 50, 939-947.
Rat Liver Tissue<br />
Tsai,P.C., Fu,T.W., Chen,Y.M.A., Ko,T.L., Chen,T.H., Shih,Y.H., Hung,S.C. and Fu,Y.S. (2009) The therapeutic<br />
potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis.<br />
Liver Transplantation, 15, 484-495.<br />
Rat Glomeruli and Cultured Mesangial Cells<br />
Urushihara,M., Takamatsu,M., Shimizu,M., Kondo,S., Kinoshita,Y., Suga,K., Kitamura,A., Matsuura,S., Yoshizumi,M.<br />
and Tamaki,T. (2009) ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat<br />
progressive glomerulonephritis. American Journal of Physiology- Renal Physiology, doi:<br />
10.1152/ajprenal.00124.2009.<br />
Primary Human Cardiac Fibroblasts<br />
Venkatachalam,K., Venkatesan,B., Valente,A.J., Melby,P.C., Nandish,S., Reusch,J.E.B., Clark,R.A. and<br />
Chandrasekar,B. (2009) Wisp1, a pro-mitogenic, pro-survival factor, mediates TNF-alpha stimulated cardiac<br />
fibroblast proliferation, but inhibits TNF-alpha-induced cardiomyocyte death. Journal of <strong>Bio</strong>logical Chemistry,<br />
284, 14414-14427.<br />
Murine Diaphragm<br />
Vetrone,S.A., Montecino-Rodriguez,E., Kudryashova,E., Kramerova,I., Hoffman,E.P., Liu,S.D., Miceli,M.C. and<br />
Spencer,M.J. (2009) Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell<br />
subsets and intramuscular TGF-ß. The Journal of Clinical Investigation, 119, 1583-1594.<br />
Human Palmar Fascia Cells<br />
Vi,L., Njarlangattil,A., Wu,Y., Gan,B.S. and O'Gorman,D.B. (2009) Type-1 collagen differentially alters beta-catenin<br />
accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells. BMC Musculoskeletal<br />
Disorders, 10, 72.<br />
Human Palmar Fascia Cells<br />
Vi,L., Feng,L., Zhu,R.D., Wu,Y., Satish,L., Gan,B.S. and O'Gorman,D.B. (2009) Periostin differentially induces<br />
proliferation, contraction and apoptosis of primary Dupuytren's disease and adjacent palmar fascia cells.<br />
Experimental Cell Research, 315, 3574 – 3586.<br />
Human Smooth Muscle Cells<br />
Wang,C., Cen,L., Yin,S., Liu,Q., Liu,W., Cao,Y. and Cui,L. (2010) A small diameter elastic blood vessel wall prepared<br />
under pulsatile conditions from polyglycolic acid mesh and smooth muscle cells differentiated from adiposederived<br />
stem cells. <strong>Bio</strong>materials, 31, 621-630.<br />
Murine Colonic Fibroblast Cells<br />
Wang,H., Zhang,R., Wen,S., McCafferty,D.M., Beck,P.L. and MacNaughton,W.K. (2009) Nitric oxide increases Wntinduced<br />
secreted protein-1 (WISP-1/CCN4) expression and function in colitis. Journal of Molecular Medicine,<br />
87, 435-445.<br />
Murine Calf Muscle<br />
Watanuki,M., Kishimoto,K.N., Kotajima,S., Iwabuchi,S. and Kokubun,S. (2009) Effect of low-intensity pulsed ultrasound<br />
on scaffold-free ectopic bone formation in skeletal muscle. Upsala Journal of Medical Sciences, 114, 242-248.<br />
Rat Stellate Liver Cell Line (HSC-T6)<br />
Weng,T.C., Shen,C.C., Chiu,Y.T., Lin,Y.L., Kuo,C.D. and Huang,Y.T. (2009) Inhibitory effects of armepavine against<br />
hepatic fibrosis in rats. Journal of <strong>Bio</strong>medical Science, 16, 78.
Murine Lung Tissue<br />
Wigenstam,E., Rocksén,D., Ekstrand-Hammarström,B. and Bucht,A. (2009) Treatment with dexamethasone or<br />
liposome-encapsuled vitamin E provides beneficial effects after chemical-induced lung injury. Inhalation<br />
Toxicology, 11, 958-964.<br />
Murine Skin and Lung Tissue<br />
Wu,M., Melichian,D.S., de la Garza,M., Gruner,K., Bhattacharyya,S., Barr,L., Nair,A., Shahrara,S., Sporn,P.H.S. and<br />
Mustoe,T.A. (2009) Essential Roles for Early Growth Response Transcription Factor Egr-1 in Tissue Fibrosis and<br />
Wound Healing. American Journal of Pathology, 175, 1041.<br />
Murine Model of Scleroderma<br />
Wu,M., Melichian,D.S., Chang,E., Warner-Blankenship,M., Ghosh,A.K. and Varga,J. (2009) Rosiglitazone Abrogates<br />
Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated<br />
Receptor-γ. American Journal of Pathology, 174, 519.<br />
Rat Liver Tissue<br />
Yasoshima,M., Sato,Y., Furubo,S., Kizawa,K., Sanzen,T., Ozaki,S., Harada,K. and Nakanuma,Y. (2009) Matrix proteins<br />
of basement membrane of intrahepatic bile ducts are degraded in congenital hepatic fibrosis and Caroli's<br />
disease No conflicts of interest were declared. The Journal of Pathology, 217, 442-451.<br />
Porcine Hind Leg Tibial Osteochondral Explants<br />
Yeow,C.H., Lau,S.T., Lee,P.V.S. and Goh,J.C.H. (2009) Damage and degenerative changes in menisci-covered and<br />
exposed tibial osteochondral regions after simulated landing impact compression-a porcine study. Journal of<br />
Orthopaedic Research, 27, 1100-1108.<br />
Equine Tendon Tissue<br />
Young,N.J., Becker,D.L., Fleck,R.A., Goodship,A.E. and Patterson-Kane,J.C. (2009) Maturational alterations in gap<br />
junction expression and associated collagen synthesis in response to tendon function. Matrix <strong>Bio</strong>logy, 28, 311-<br />
323.<br />
Mouse Embryonic Fibroblast Cell Line (NIH 3T3)<br />
Zhang,W., Rong,J., Wang,Q. and He,X. (2009) The encapsulation and intracellular delivery of trehalose using a<br />
thermally responsive nanocapsule. Nanotechnology, 20, 275101.<br />
Mouse Model of Atopic Dermatitis<br />
Zheng,T., Oh,M., Oh,S., Wu,F., Myers,A. and Zhu,Z. (2009) IL-13 Regulation of Skin Remodeling in a Mouse Model of<br />
Atopic Dermatitis. The Journal of Allergy and Clinical Immunology, 123, 35.<br />
Murine Lung Tissue<br />
Zhou,Y., Mohsenin,A., Morschl,E., Young,H.W.J., Molina,J.G., Ma,W., Sun,C.X., Martinez-Valdez,H. and Blackburn,M.R.<br />
(2009) Enhanced Airway Inflammation and Remodeling in Adenosine Deaminase-Deficient Mice Lacking the A2B<br />
Adenosine Receptor. The Journal of Immunology, 182, 8037-8046.<br />
2008<br />
Mouse Model of Dermal Fibrosis<br />
Akhmetshina,A., Dees,C., Pileckyte,M., Maurer,B., Axmann,R., Jungel,A., Zwerina,J., Gay,S., Schett,G. and Distler,O.<br />
(2008) Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of<br />
dermal fibrosis. The FASEB Journal, 22, 2214-2222.
Scleroderma Fibroblasts<br />
Akhmetshina,A., Dees,C., Pileckyte,M., Szucs,G., Spriewald,B.M., Zwerina,J., Distler,O., Schett,G. and Distler,J.H.<br />
(2008) Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular<br />
matrix in scleroderma fibroblasts. Arthritis Rheum, 58, 2553-2564.<br />
Rabbit Bone Marrow Cells Seeded on Porcine Small Intestine Submucosa<br />
Almarza,A.J., Yang,G., Woo,S.L.Y., Nguyen,T. and Abramowitch,S.D. (2008) Positive Changes in Bone Marrow-Derived<br />
Cells in Response to Culture on an Aligned <strong>Bio</strong>scaffold. Tissue Engineering, 14, 1489-1495.<br />
Human Lung Fibroblasts<br />
Antao-Menezes,A., Turpin,E.A., Bost,P.C., Ryman-Rasmussen,J.P. and Bonner,J.C. (2008) STAT-1 Signaling in Human<br />
Lung Fibroblasts Is Induced by Vanadium Pentoxide through an IFN-beta Autocrine Loop. The Journal of<br />
Immunology, 180, 4200-4207.<br />
Cultured Human Intrahepatic (Myo) Fibroblasts (hIHFs)<br />
Aoudjehane,L., Pissaia,A., Scatton,O., Podevin,P., Massault,P.P., Chouzenoux,S., Soubrane,O., Calmus,Y. and Conti,F.<br />
(2008) Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts<br />
via the STAT-6 pathway. Laboratory Investigation, 88, 973-985.<br />
Human Dermal Fibroblasts<br />
Bhogal, R.K. and Bona, C.A. (2008) Regulatory Effect of Extracellular Signal- Regulated Kinases (ERK) on Type I<br />
Collagen Synthesis in Human Dermal Fibroblasts Stimulated by IL-4 and IL-13. International Reviews of<br />
Immunology, 27, 472 – 496.<br />
Porcine Valvular Interstitial Cells from Various Regions of the Mitral Valve<br />
Blevins,T.L., Peterson,S.B., Lee,E.L., Bailey,A.M., Frederick,J.D., Huynh,T.N., Gupta,V. and Grande-Allen,K. (2008)<br />
Mitral Valvular Interstitial Cells Demonstrate Regional, Adhesional, and Synthetic Heterogeneity. Cells Tissues<br />
Organs, 187, 113-122.<br />
Human Lung Fibroblasts and Mouse Bleomycin Induced Lung Fibrosis<br />
Borie,R., Fabre,A., Prost,F., Marchal-Somme,J., Lebtahi,R., Marchand-Adam,S., Aubier,M., Soler,P. and Crestani,B.<br />
(2008) Activation of somatostatin receptors attenuates pulmonary fibrosis. Thorax, 63, 251-258.<br />
An Alloxan Rabbit Ear Ulcer Model<br />
Breen,A.M., Dockery,P., O'Brien,T. and Pandit,A.S. (2008) The use of therapeutic gene eNOS delivered via a fibrin<br />
scaffold enhances wound healing in a compromised wound model. <strong>Bio</strong>materials, 29, 3143-3151.<br />
Polycarbonate Track-Etched Membranes<br />
Bueno,E.M. and Ruberti,J.W. (2008) Optimizing collagen transport through track-etched nanopores. Journal of<br />
Membrane Science, 321, 250-263.<br />
Human Lung Fibroblasts<br />
Caraci,F., Gili,E., Calafiore,M., Failla,M., La Rosa,C., Crimi,N., Sortino,M.A., Nicoletti,F., Copani,A. and Vancheri,C.<br />
(2008) TGF-β1 targets the GSK-3β/β-catenin pathway via ERK activation in the transition of human lung<br />
fibroblasts into myofibroblasts. Pharmacological Research, 57, 274-282.<br />
Fetal Rat Lung Tissue<br />
Chen,C.M., Chou,H.C., Wang,L.F. and Lang,Y.D. (2008) Experimental Oligohydramnios Decreases Collagen in<br />
Hypoplastic Fetal Rat Lungs. Experimental <strong>Bio</strong>logy and Medicine, 233, 1334-1340.
Rabbit Digitorum Extensor Tendon<br />
Chen,C.H., Liu,H.W., Tsai,C.L., Yu,C.M. and Lin,I. (2008) Photoencapsulation of Bone Morphogenetic Protein-2 and<br />
Periosteal Progenitor Cells Improve Tendon Graft Healing in a Bone Tunnel. The American Journal of Sports<br />
Medicine, 36, 461-473.<br />
Murine Osteoblastic MC3T3-E1 Cells<br />
Choi,E.M. and Kim,Y.H. (2008) Hesperetin attenuates the highly reducing sugar-triggered inhibition of osteoblast<br />
differentiation. Cell <strong>Bio</strong>logy and Toxicology, 24, 225-231.<br />
Bone Marrow Derived Mesenchymal Stem Cells (MSCs)<br />
Choi,K.M., Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S. and Park,J.K. (2008) Effect of ascorbic acid on bone<br />
marrow-derived mesenchymal stem cell proliferation and differentiation. Journal of <strong>Bio</strong>science and<br />
<strong>Bio</strong>engineering, 105, 586-594.<br />
Rabbit Autologous Cells from Vaginal <strong>Bio</strong>psy<br />
De Philippo,R.E., Bishop,C.E., Freitas Filho,L., Yoo,J.J. and Atala,A. (2008) Tissue Engineering a Complete Vaginal<br />
Replacement From a Small <strong>Bio</strong>psy of Autologous Tissue. Transplantation, 86, 208-214.<br />
Human Fibroblasts from Systemic Sclerotic Patients<br />
Distler,J.H.W., Akhmetshina,A., Schett,G. and Distler,O. (2008) Monocyte chemoattractant proteins in the<br />
pathogenesis of systemic sclerosis. Rheumatology, 48, 98-103.<br />
Atherosclerotic Lesions in Apo-E-Deficient Mice<br />
Do,G.M., Kwon,E.Y., Kim,H.J., Jeon,S.M., Ha,T.Y., Park,T. and Choi,M.S. (2008) Long-term effects of resveratrol<br />
supplementation on suppression of atherogenic lesion formation and cholesterol synthesis in apo E-deficient<br />
mice. <strong>Bio</strong>chemical and <strong>Bio</strong>physical Research Communications, 374, 55-59.<br />
Rat Lung Tissue<br />
Elgrabli,D., bella-Gallart,S., Robidel,F., Rogerieux,F., Boczkowski,J. and Lacroix,G. (2008) Induction of apoptosis and<br />
absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes.<br />
Toxicology, 253, 131-136.<br />
Murine Lung Tissue<br />
Fabre,A., Marchal-Somme,J., Marchand-Adam,S., Quesnel,C., Borie,R., Dehoux,M., Ruffie,C., Callebert,J., Launay,J.M.<br />
and Henin,D. (2008) Modulation of bleomycin induced lung fibrosis by serotonin receptor antagonists in mice.<br />
European Respiratory Journal, doi:10.1183/09031936-00126907.<br />
Murine Lung Tissue<br />
Failla,M., Genovese,T., Mazzon,E., Fruciano,M., Fagone,E., Gili,E., Barera,A., La Rosa,C., Conte,E., Crimi,N.,<br />
Cuzzocrea, S. and Vaneheri, C. (2008) 16, 16-Dimethyl Prostaglandin E2 Efficacy on Prevention and Protection<br />
from Bleomycin-induced Lung Injury and Fibrosis. American Journal of Respiratory Cell and Molecular <strong>Bio</strong>logy,<br />
doi:10.1165/rcmb.2007-04380C.<br />
Mesenchymal Stem Cells<br />
Fan,H., Liu,H., Toh,S.L. and Goh,J.C.H. (2008) Enhanced differentiation of mesenchymal stem cells co-cultured with<br />
ligament fibroblasts on gelatin/silk fibroin hybrid scaffold. <strong>Bio</strong>materials, 29, 1017-1027.<br />
Mesenchymal Stem Cells and Silk Scaffold<br />
Fan,H., Liu,H., Wong,E.J.W., Toh,S.L. and Goh,J.C.H. (2008) In vivo study of anterior cruciate ligament regeneration<br />
using mesenchymal stem cells and silk scaffold. <strong>Bio</strong>materials, 29, 3324-3337.
Murine Intestinal Myofibroblasts<br />
Fichtner-Feigl,S., Young,C.A., Kitani,A., Geissler,E.K., Schlitt,H.J. and Strober,W. (2008) IL-13 Signaling via IL-13Ra2<br />
Induces Major Downstream Fibrogenic Factors Mediating Fibrosis in Chronic TNBS Colitis. Gastroenterology,<br />
135, 2003-2013.e7.<br />
Bone Marrow Samples<br />
Freyman, T. (2008) Decellularized bone marrow extracellular matrix. US Patent 7326571.<br />
Cartilage Tissue<br />
Furukawa,K.S., Imura,K., Tateishi,T. and Ushida,T. (2008) Scaffold-free cartilage by rotational culture for tissue<br />
engineering. Journal of <strong>Bio</strong>technology, 133, 134-145.<br />
Collagen Based Scaffolds<br />
Garcia,Y., Wilkins,B., Collighan,R.J., Griffin,M. and Pandit,A. (2008) Towards development of a dermal rudiment for<br />
enhanced wound healing response. <strong>Bio</strong>materials, 29, 857-868.<br />
Hepatic Stellate Cells<br />
Gardi,C., Arezzini,B., Monaco,B., De Montis,M.G., Vecchio,D. and Comporti,M. (2008) F 2-isoprostane receptors on<br />
hepatic stellate cells. Laboratory Investigation, 88, 124-131.<br />
ECM Model of Fibroblast Monolayer and Endothelial Cell-Coated Beads<br />
Ghajar,C.M., Chen,X., Harris,J.W., Suresh,V., Hughes,C.C.W., Jeon,N.L., Putnam,A.J. and George,S.C. (2008) The<br />
Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis. <strong>Bio</strong>physical Journal, 94, 1930-1941.<br />
Human Carotid Plaques<br />
Gonçalves, I., Ares, M.P.S., Moberg, A., Moses, J., To, F., Montan, J., Pedro, L.M., Dias, N., e Fernandes, J.F.,<br />
Fredrikson, G.N., Nilsson, J., Jovinge, S. and Bengtsson, E. (2008) Elastin- and Collagen-Rich Human Carotid<br />
Plaques Have Increased Levels of the Cysteine Protease Inhibitor Cystatin C. Journal of Vascular Research, 45,<br />
395 – 401.<br />
Murine Intestinal Tissue<br />
Grassl,G.A., Valdez,Y., Bergstrom,K.S.B., Vallance,B.A. and Finlay,B.B. (2008) Chronic Enteric Salmonella Infection in<br />
Mice Leads to Severe and Persistent Intestinal Fibrosis. Gastroenterology, 134,768-780.e2.<br />
293 T-Rex Cell Line<br />
Greenspan,D., Zhang,Y. and GE,G. (2008) Method and composition for treating a fibrotic disorder. WIPO Patent<br />
Application WO/2008/024767.<br />
Porcine Valvular Interstitial Cells from Distinct Regions of Mitral Valve<br />
Gupta,V., Werdenberg,J.A., Mendez,J.S. and Jane Grande-Allen,K. (2008) Influence of strain on proteoglycan synthesis<br />
by valvular interstitial cells in three-dimensional culture. Acta <strong>Bio</strong>materialia, 4, 88-96.<br />
Porcine Valvular Interstitial Cells from Valve Leaflet and Chordae<br />
Gupta,V., Werdenberg,J.A., Lawrence,B.D., Mendez,J.S., Stephens,E.H. and Grande-Allen,K.J. (2008) Reversible<br />
Secretion of Glycosaminoglycans and Proteoglycans by Cyclically Stretched Valvular Cells in 3D Culture. Annals<br />
of <strong>Bio</strong>medical Engineering, 36, 1092-1103.
Demineralized Bone Matrix<br />
Han,B., Yang,Z. and Nimni,M. (2008) Effects of gamma irradiation on osteoinduction associated with demineralized<br />
bone matrix. Journal of Orthopaedic Research, 26, 75-82.<br />
Murine Lung Tissue<br />
Hardie,W.D., Davidson,C., Ikegami,M., Leikauf,G.D., Le Cras,T.D., Prestridge,A., Whitsett,J.A. and Korfhagen,T.R.<br />
(2008) EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-α-induced pulmonary<br />
fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294, L1217-L1225.<br />
Rabbit Fibrocartilaginous Tissues<br />
Hashem,G., Zhang,Q., Hayami,T., Chen,J., Wang,W. and Kapila,S. (2008) Relaxin and β-estradiol modulate targeted<br />
matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss. Arthritis<br />
Research and Therapy, 8, R98.<br />
Murine Lung Tissue<br />
Hashimoto,S., Amaya,F., Matsuyama,H., Ueno,H., Kikuchi,S., Tanaka,M., Watanabe,Y., Ebina,M., Ishizaka,A. and<br />
Tsukita,S. (2008) Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal<br />
bleomycin. American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L566-L574.<br />
Human Annulus Fibrosus (HAF) Cells<br />
Helen,W. and Gough,J.E. (2008) Cell viability, proliferation and extracellular matrix production of human annulus<br />
fibrosus cells cultured within PDLLA/<strong>Bio</strong>glass® composite foam scaffolds in vitro. Acta <strong>Bio</strong>materialia, 4, 230-<br />
243.<br />
Murine Lung Tissue<br />
Hirata,H., Arima,M., Fukushima,Y., Ishii,Y., Tokuhisa,T. and Fukuda,T. (2008) Effects of Th2 pulmonary inflammation<br />
in mice with bleomycin-induced pulmonary fibrosis. Respirology, 13, 788-798.<br />
Murine Liver Tissue<br />
Hisamori,S., Tabata,C., Kadokawa,Y., Okoshi,K., Tabata,R., Mori,A., Nagayama,S., Watanabe,G., Kubo,H. and Sakai,Y.<br />
(2008) All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through<br />
modulating cytokine production. Liver International, 28, 1217-1225.<br />
Rat Mesenchymal Stem Cells and Porcine Aortic Valve Leaflets.<br />
Hong,H., Dong,G.N., Shi,W.J., Chen,S., Guo,C. and Hu,P. (2008) Fabrication of <strong>Bio</strong>matrix/Polymer Hybrid Scaffold for<br />
Heart Valve Tissue Engineering in Vitro. ASAIO Journal, 54, 627-632.<br />
Murine Dorsum<br />
Hong,H.J., Jin,S.E., Park,J.S., Ahn,W.S. and Kim,C.K. (2008) Accelerated wound healing by smad3 antisense<br />
oligonucleotides-impregnated chitosan/alginate polyelectrolyte complex. <strong>Bio</strong>materials, 29, 4831-4837.<br />
Mouse Model of Scleroderma<br />
Hoyles,R.K., Khan,K., Shiwen,X., Howat,S.L., Lindahl,G.E., Leoni,P., du Bois,R.M., Wells,A.U., Black,C.M. and<br />
Abraham,D.J. (2008) Fibroblast-Specific Perturbation of Transforming Growth Factor Signaling Provides Insight<br />
Into Potential Pathogenic Mechanisms of Scleroderma-Associated Lung Fibrosis. Arthritis & Rheumatism, 58,<br />
1175-1188.
Mouse Cardiac Fibroblasts<br />
Hu,C., Dandapat,A., Sun,L., Khan,J.A., Liu,Y., Hermonat,P.L. and Mehta,J.L. (2008) Regulation of TGF β1-mediated<br />
Collagen Formation by LOX-1: Studies Based on Forced Overexpression of TGF β1 in Wild-Type and LOX-1<br />
Knock-Out Mouse Cardiac Fibroblasts. Journal of <strong>Bio</strong>logical Chemistry, 283, 10226-10231.<br />
Human Cartilage Culture and a Rabbit Model of Osteoarthritis<br />
Huh,J.E., Baek,Y.H., Ryu,S.R., Lee,J.D., Choi,D.Y. and Park,D.S. (2008) Efficacy and mechanism of action of KHBJ-9B,<br />
a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model<br />
of collagenase-induced osteoarthritis. International Immunopharmacology, 9, 230-240.<br />
Osteoblasts In Vitro and Calvarial Osteoblasts In Vivo<br />
Idris,A.I., Rojas,J., Greig,I.R., van’t Hof,R.J. and Ralston,S.H. (2008) Aminobisphosphonates Cause Osteoblast<br />
Apoptosis and Inhibit Bone Nodule Formation In Vitro. Calcified Tissue International, 82, 191-201.<br />
Murine Cardiac Tissue<br />
Inagaki,K., Koyanagi,T., Berry,N.C., Sun,L. and Mochly-Rosen,D. (2008) Pharmacological Inhibition of ε-Protein Kinase C<br />
Attenuates Cardiac Fibrosis and Dysfunction in Hypertension-Induced Heart Failure. Hypertension, 51, 1565.<br />
Human Periodontal Ligament Cell Line (HPL)<br />
Inubushi,T., Tanaka,E., Rego,E.B., Kitagawa,M., Kawazoe,A., Ohta,A., Okada,H., Koolstra,J.H., Miyauchi,M. and<br />
Takata,T. (2008) Effects of Ultrasound on the proliferation and differentiation of Cementoblast lineage Cells.<br />
Journal of Periodontology, 79, 1-2.<br />
Primary Hepatic Stellate Cells from Wild Type and Sept 4-/-Mice<br />
Iwaisako,K., Hatano,E., Taura,K., Nakajima,A., Tada,M., Seo,S., Tamaki,N., Sato,F., Ikai,I. and Uemoto,S. (2008) Loss<br />
of Sept4 exacerbates liver fibrosis through the dysregulation of hepatic stellate cells. Journal of Hepatology,<br />
49, 768-778.<br />
Murine Lung Tissue<br />
Kakizaki,T., Kohno,M., Watanabe,M., Tajima,A., Izumi,Y., Miyasho,T., Tasaka,S., Fukunaga,K., Maruyama,I. and<br />
Ishizaka,A. (2008) Exacerbation of Bleomycin-Induced Injury and Fibrosis by Pneumonectomy in the Residual<br />
Lung of Mice. Journal of Surgical Research, doi:10.1016/j.jss.2008.06.021.<br />
Rat Renal Tissue and Cultured Mesangial Cells<br />
Kang,Y.S., Ko,G.J., Lee,M.H., Song,H.K., Han,S.Y., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2008) Effect of<br />
eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats.<br />
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfn448.<br />
Murine Skin<br />
Kanno,Y., Kaneiwa,A., Minamida,M., Kanno,M., Tomogane,K., Takeuchi,K., Okada,K., Ueshima,S., Matsuo,O. and<br />
Matsuno,H. (2008) The Absence of uPAR Is Associated with the Progression of Dermal Fibrosis. Journal of<br />
Investigative Dermatology, doi:10.1038/jid.2008.157.<br />
Human Gingival Fibroblasts<br />
Kim,J.Y., Park,S.H., Cho,K.S., Kim,H.J., Lee,C.K., Park,K.K., Choi,S.H. and Chung,W.Y. (2008) Mechanism of<br />
Azithromycin Treatment on Gingival Overgrowth. Journal of Dental Research, 87, 1075.
Mouse Primary and NIH/3T3 Fibroblasts<br />
Kitowska,K., Zakrzewicz,D., Königshoff,M., Chrobak,I., Grimminger,F., Seeger,W., Bulau,P. and Eickelberg,O. (2008)<br />
Functional role and species-specific contribution of arginases in pulmonary fibrosis. American Journal of<br />
Physiology- Lung Cellular and Molecular Physiology, 294, L34-L45.<br />
Rat Renal Tissue and Cultured Mesangial Cells<br />
Ko,G.J., Kang,Y.S., Han,S.Y., Lee,M.H., Song,H.K., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2008) Pioglitazone<br />
attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Nephrology<br />
Dialysis Transplantation, 23, 2750-2760.<br />
Lung Epithelial Cells<br />
Königshoff,M., Balsara,N., Pfaff,E.M., Kramer,M., Chrobak,I., Seeger,W. and Eickelberg,O. (2008) Functional Wnt<br />
Signaling Is Increased in Idiopathic Pulmonary Fibrosis. PLoS ONE, 3 (5) e2142.doi:1371/journal.pone.0002142.<br />
Rat Bone Marrow-Derived Mesenchymal Stromal Cells (BMSCs)<br />
Kwon,D.S., Gao,X., Liu,Y.B., Dulchavsky,D.S., Danyluk,A.L., Bansal,M., Chopp,M., McIntosh,K., Arbab,A.S. and<br />
Dulchavsky,S.A. (2008) Treatment with bone marrow-derived stromal cells accelerates wound healing in<br />
diabetic rats. International Wound Journal, 5, 453-463.<br />
Mouse Osteoblastic MC3T3-E1 Cell Line<br />
Lee,K.H. and Choi,E.M. (2008) Myricetin, a naturally occurring flavonoid, prevents 2-deoxy-d-ribose induced<br />
dysfunction and oxidative damage in osteoblastic MC3T3-E1 cells. European Journal of Pharmacology, 591, 1-<br />
6.<br />
Murine Lung Tissue<br />
Lee,K.S., Park,S.J., Kim,S.R., Min,K.H., Lee,K.Y., Choe,Y.H., Hong,S.H., Lee,Y.R., Kim,J.S. and Hong,S.J. (2008)<br />
Inhibition of VEGF blocks TGF-β1 production through a PI3K/Akt signalling pathway. European Respiratory<br />
Journal, 31, 523-531.<br />
Murine Tissue<br />
Lee,S.J., Van Dyke,M., Atala,A. and Yoo,J.J. (2008) Host Cell Mobilization for In Situ Tissue Regeneration.<br />
Rejuvenation Research, 11, 747-756.<br />
Murine Lung Tissue<br />
Le Saux,O., Teeters,K., Miyasato,S., Choi,J., Nakamatsu,G., Richardson,J.A., Starcher,B., Davis,E.C., Tam,E.K. and<br />
Jourdan-Le Saux,C. (2008) The role of caveolin-1 in pulmonary matrix remodeling and mechanical properties.<br />
American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L1007-L1017.<br />
Renal Tissue of Zucker Diabetic Fatty Rats<br />
Li,Y., Qi,Y., Kim,M.S., Xu,K.Z., Huang,T.H., Rong,X., Murray,M. and Yamahara,J. (2008) Increased renal collagen crosslinking<br />
and lipid accumulation in nephropathy of Zucker diabetic fatty rats. Diabetes Metab Res Rev., 24, 498-<br />
506.<br />
Cardiac Fibroblasts<br />
Lijnen,P., Petrov,V., van Pelt,J. and Fagard,R. (2008) Inhibition of Superoxide Dismutase Induces Collagen Production<br />
in Cardiac Fibroblasts. American Journal of Hypertension, 21, 1129-1136.
Human Lung Tissue from Patients with Idiopathic Pulmonary Fibrosis and Human Fibroblasts<br />
Lin,L., Zhou,Z., Zheng,L., Alber,S., Watkins,S., Ray,P., Kaminski,N., Zhang,Y. and Morse,D. (2008) Cross Talk between<br />
Id1 and Its Interactive Protein Dril1 Mediate Fibroblast Responses to Transforming Growth Factor-β in<br />
Pulmonary Fibrosis. American Journal of Pathology, 173, 337-346.<br />
Rat Hepatic Stellate Cell Line (HSC-T6)<br />
Lin,Y.L., Wu,C.F. and Huang,Y.T. (2008) Effects of rhubarb on migration of rat hepatic stellate cells. Journal of<br />
Gastroenterology and Hepatology, doi:10.1111/j.1440-1746.2008.05573.x.<br />
Osteoblasts<br />
Liu,H., Yazici,H., Ergun,C., Webster,T.J. and Bermek,H. (2008) An in vitro evaluation of the Ca/P ratio for the<br />
cytocompatibility of nano-to-micron particulate calcium phosphates for bone regeneration. Acta <strong>Bio</strong>materialia,<br />
4, 1472-1479.<br />
Normal Human Bronchial Epithelial Cells<br />
Malavia,N.K., Mih,J.D., Raub,C.B., Dinh,B.T., George,S.C., Tirumurugaan,K.G., Kang,B.N., Panettieri,R.A., Foster,D.N.<br />
and Walseth,T.F. (2008) IL-13 induces a bronchial epithelial phenotype that is profibrotic. Respiratory<br />
Research, 9, 27.<br />
Leiomyoma and Myometrial Cells<br />
Malik,M., Webb,J. and Catherino,W.H. (2008) Retinoic acid treatment of human leiomyoma cells transformed the cell<br />
phenotype to one strongly resembling myometrial cells. Clinical Endocrinology, 69, 462-470.<br />
Rat Cardiomyocytes<br />
Mancuso,P., Rahman,A., Hershey,S.D., Dandu,L., Nibbelink,K.A. and Simpson,R.U. (2008) 1, 25-Dihydroxyvitamin-D3<br />
Treatment Reduces Cardiac Hypertrophy and Left Ventricular Diameter in Spontaneously Hypertensive Heart<br />
Failure-prone (cp/+) Rats Independent of Changes in Serum Leptin. Journal of Cardiovascular Pharmacology,<br />
51, 559-564.<br />
Murine Model of Plexiform Neurofibroma<br />
McDaniel,A.S. (2008) The role of PAK1 in the cellular and molecular components of plexiform neurofibromas.<br />
http://hdl.handle.net/1805/1696<br />
Human Lung Fibroblasts and Myofibroblasts<br />
Milam,J.E., Keshamouni,V.G., Phan,S.H., Hu,B., Gangireddy,S.R., Hogaboam,C.M., Standiford,T.J., Thannickal,V.J.<br />
and Reddy,R.C. (2008) PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycininduced<br />
pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294,<br />
L891-L901.<br />
Human Retinal Pigment Epithelial (ARPE-19) Cell Line<br />
Morales,S.A., Mareninov,S., Wadehra,M., Zhang,L., Goodglick,L., Braun,J. and Gordon,L.K. (2008) Epithelial Membrane<br />
Protein 2 (EMP2) Controls Collagen Gel Contraction in ARPE-19 Cells by Modulating FAK Activation.<br />
Investigative Ophthalmology & Visual Science, doi:10:1167/iovs.07-1598.<br />
Murine Lung Tissue<br />
Mozaffarian,A., Brewer,A.W., Trueblood,E.S., Luzina,I.G., Todd,N.W., Atamas,S.P. and Arnett,H.A. (2008) Mechanisms<br />
of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis. The Journal of Immunology, 181, 7243.
Human IPF/UIP Fibroblasts<br />
Murray,L.A., Argentieri,R.L., Farrell,F.X., Bracht,M., Sheng,H., Whitaker,B., Beck,H., Tsui,P., Cochlin,K. and<br />
Evanoff,H.L. (2008) Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2.<br />
International Journal of <strong>Bio</strong>chemistry and Cell <strong>Bio</strong>logy, 40, 2174-2182.<br />
Human Lung Fibroblasts<br />
Murray,L.A., Hackett,T.L., Warner,S.M., Shaheen,F., Argentieri,R.L., Dudas,P., Farrell,F.X. and Knight,D.A. (2008)<br />
BMP-7 Does Not Protect against Bleomycin-Induced Lung or Skin Fibrosis. PLoS ONE, 3,e4039.<br />
Bovine Articular Cartilage<br />
Natoli,R.M., Scott,C.C. and Athanasiou,K.A. (2008) Temporal Effects of Impact on Articular Cartilage Cell Death, Gene<br />
Expression, Matrix <strong>Bio</strong>chemistry, and <strong>Bio</strong>mechanics. Annals of <strong>Bio</strong>medical Engineering, 36, 780-792.<br />
Murine Model of Liver Cirrhosis<br />
Nishibe,Y., Kaneko,H., Suzuki,H., Abe,T., Matsuura,Y. and Takaku,H. (2008) Baculovirus-mediated interferon alleviates<br />
dimethylnitrosamine-induced liver cirrhosis symptoms in a murine model. Gene Therapy, 15, 990-997.<br />
Horse Superficial Digital Flexor Tendon<br />
Nixon,A.J., Dahlgren,L.A., Haupt,J.L., Yeager,A.E. and Ward,D.L. (2008) Effect of adipose-derived nucleated cell<br />
fractions on tendon repair in horses with collagenase-induced tendinitis. American Journal of Veterinary<br />
Research, 69, 928-937.<br />
Rat Mesenchymal Stem Cells<br />
Ocarino,N.M., Boeloni,J.N., Goes,A.M., Silva,J.F., Marubayashi,U. and Serakides,R. (2008) Osteogenic differentiation of<br />
mesenchymal stem cells from osteopenic rats subjected to physical activity with and without nitric oxide<br />
synthase inhibition. Nitric Oxide, 19,320-325.<br />
Murine Intestinal Tissue<br />
Okoshi,K., Kubo,H., Nagayama,S., Tabata,C., Kadokawa,Y., Hisamori,S., Yonenaga,Y., Fujimoto,A., Mori,A. and<br />
Onodera,H. (2008) All-trans-Retinoic Acid Attenuates Radiation-Induced Intestinal Fibrosis in Mice. Journal of<br />
Surgical Research, 150, 53-59.<br />
Normal Human Lung Fibroblast (NHLF) Cells<br />
Pandey, A., Scarborough, R. M., and Venkatraman, M. S. (2008) Compositions and methods for inhibiting TGF-β. US<br />
Patent 7314939.<br />
Human Dermal Fibroblasts<br />
Park,H.J., Cho,D.H., Kim,H.J., Lee,J.Y., Cho,B.K., Bang,S.I., Song,S.Y., Yamasaki,K., Di Nardo,A. and Gallo,R.L. (2008)<br />
Collagen Synthesis Is Suppressed in Dermal Fibroblasts by the Human Antimicrobial Peptide LL-37. Journal of<br />
Investigative Dermatology, doi:10.1038/jid.2008.320.<br />
Rabbit Mesenchymal Cells<br />
Park,K.H. and Na,K. (2008) Effect of growth factors on chondrogenic differentiation of rabbit mesenchymal cells<br />
embedded in injectable hydrogels. Journal of <strong>Bio</strong>science and <strong>Bio</strong>engineering, 106, 74-79.<br />
Human Mesenchymal Stem Cells<br />
Richardson,S.M., Hughes,N., Hunt,J.A., Freemont,A.J. and Hoyland,J.A. (2008) Human mesenchymal stem cell<br />
differentiation to NP-like cells in chitosan-glycerophosphate hydrogels. <strong>Bio</strong>materials, 29, 85-93.
Normal Human Lung Fibroblast (NHLF) Cells<br />
Scarborough, R. M., Pandey, A., and Mehrotra, M. (2008) Compositions and method for inhibiting TGF-β. US Patent<br />
7361669.<br />
Lacrimal Gland Extra Cellular Matrix from Healthy (BALB/C) and Diseased (NOD) Mice<br />
Schenke-Layland,K., Xie,J., Angelis,E., Starcher,B., Wu,K., Riemann,I., MacLellan,W.R. and Hamm-Alvarez,S.F. (2008)<br />
Increased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of<br />
Sjögren's syndrome. Matrix <strong>Bio</strong>logy, 27, 53-66.<br />
Human Anterior Cruciate Ligament Cell and T-Lymphocyte Cultures<br />
Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S. and Park,J.K. (2008) Increase in cell migration and<br />
angiogenesis in a composite silk scaffold for tissue-engineered ligaments. Journal of Orthopaedic Research:<br />
doi:1002/jor.20752.<br />
Mouse Model of Dermal Fibrosis<br />
Shibusawa,Y., Negishi,I., Tabata,Y. and Ishikawa,O. (2008) Mouse model of dermal fibrosis induced by one-time<br />
injection of bleomycin-poly (L-lactic acid) microspheres. Rheumatology, 47, 454-457.<br />
Several Tumor Cell Lines<br />
Shimazaki,M. and Kudo,A. (2008) Impaired capsule formation of tumors in periostin-null mice. <strong>Bio</strong>chemical and<br />
<strong>Bio</strong>physical Research Communications, 367, 736-742.<br />
Murine Lung Tissue<br />
Shofer,S., Badea,C., Qi,Y., Potts,E., Foster,W.M. and Johnson,G.A. (2008) A micro-CT analysis of murine lung<br />
recruitment in bleomycin-induced lung injury. Journal of Applied Physiology, 105, 669-677.<br />
Murine Lung Tissue<br />
Shvedova,A.A., Kisin,E., Murray,A.R., Johnson,V.J., Gorelik,O., Arepalli,S., Hubbs,A.F., Mercer,R.R., Keohavong,P. and<br />
Sussman,N. (2008) Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation,<br />
fibrosis, oxidative stress, and mutagenesis. American Journal of Physiology- Lung Cellular and Molecular<br />
Physiology, 295, L552-L565.<br />
Human Fibroblast Cultures from Healthy Patients and Patients with Systemic Sclerosis (SSC)<br />
Skhirtladze,C., Distler,O., Dees,C., Akhmetshina,A., Busch,N., Venalis,P., Zwerina,J., Spriewald,B., Pileckyte,M. and<br />
Schett,G. (2008) Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis.<br />
Arthritis and Rheumatism, 58, 1475-1484.<br />
Cultured Mesangial Cells<br />
Song,H.K., Lee,M.H., Kim,B.K., Park,Y.G., Ko,G.J., Kang,Y.S., Han,J.Y., Han,S.Y., Han,K.H. and Kim,H.K. (2008)<br />
Visfatin: A New Player in Mesangial Cell Physiology and Diabetic Nephropathy. American Journal of Physiology-<br />
Renal Physiology, doi:10:1152/ajprenal.90231.2008.<br />
Osteoblasts<br />
Souza,D.M., Andrade,A.L., Fabris,J.D., Valério,P., Góes,A.M., Leite,M.F. and Domingues,R.Z. (2008) Synthesis and in<br />
vitro evaluation of toxicity of silica-coated magnetite nanoparticles. Journal of Non-Crystalline Solids, 354,<br />
4894-4897.
Primary Cultures of Dermal Papilla Cells, Dermal Sheath Cells and Interfollicular Dermal Fibroblasts from<br />
Female Temporo-Occipital Scalp<br />
Stevenson,S., Taylor,A.H., Meskiri,A., Sharpe,D.T. and Thornton,M.J. (2008) Differing responses of human follicular<br />
and nonfollicular scalp cells in an in vitro wound healing assay: Effects of estrogen on vascular endothelial<br />
growth factor secretion. Wound Repair and Regeneration, 16, 243-253.<br />
Dermis Extracellular Matrix<br />
Sun,W.Q. and Leung,P. (2008) Calorimetric study of extracellular tissue matrix degradation and instability after gamma<br />
irradiation. Acta <strong>Bio</strong>materialia, 4, 817-826.<br />
Rat Pancreatic Stellate Cells and Rat Pancreatic Acinar Cells<br />
Tahara,J., Shimizu,K. and Shiratori,K. (2008) Engulfment of Necrotic Acinar Cells by Pancreatic Stellate Cells Inhibits<br />
Pancreatic Fibrogenesis. Pancreas, 37, 69-74.<br />
Murine Lung Tissue<br />
Tourdot,S., Mathie,S., Hussell,T., Edwards,L., Wang,H., Openshaw,P.J.M., Schwarze,J. and Lloyd,C.M. (2008)<br />
Respiratory syncytial virus infection provokes airway remodelling in allergen-exposed mice in absence of prior<br />
allergen sensitization. Clinical & Experimental Allergy, 38, 1016-1024.<br />
Murine Cardiac Tissue from Transgenic Mice<br />
Ueno,M., Suzuki,J., Zenimaru,Y., Takahashi,S., Koizumi,T., Noriki,S., Yamaguchi,O., Otsu,K., Shen,W.J. and<br />
Kraemer,F.B. (2008) Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and<br />
fibrosis in streptozotocin diabetic mice. American Journal of Physiology- Endocrinology and Metabolism, 294,<br />
E1109-E1118.<br />
Murine Lung Tissue<br />
Walters, D.M. and Kleeberger, S.R. (2008) Mouse Models of Bleomycin-Induced Pulmonary Fibrosis. Current Protocols in<br />
Pharmacology, doi: 10.1002/0471141755.ph0546s40.<br />
Murine Lung Tissue<br />
Wang,C., Abe,S., Matsuda,K., Yu,C., Li,Y., Usuki,J., Azuma,A. and Kudoh,S. (2008) Effects of Gefitinib on Radiationinduced<br />
Lung Injury in Mice. Journal of Nippon Medical School, 75, 96-105.<br />
Human Primary Lung Fibroblasts and Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis<br />
Xia,H., Diebold,D., Nho,R., Perlman,D., Kleidon,J., Kahm,J., Avdulov,S., Peterson,M., Nerva,J. and Bitterman,P.<br />
(2008) Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with<br />
idiopathic pulmonary fibrosis. Journal of Experimental Medicine, doi:10.1084/jem.20080001.<br />
Murine Lung Tissue<br />
Yamauchi,E., Shoji,S., Nishihara,M., Shimoda,T. and Nishima,S. (2008) Contribution of Lung Fibroblast Migration in the<br />
Fibrotic Process of Airway Remodelling in Asthma. Allergology International, 57, 73-78.<br />
Canine Chondrocytes<br />
Yanez,J.A., Remsberg,C.M., Vega-Villa,K.R., Miranda,N.D., Navas,J., Ohgami,Y., McCormick,D., Hughes,K., Temple,C.<br />
and Martinez,S.A. (2008) Pharmacological Evaluation of Glyco-Flex® III and its Constituents on Canine<br />
Chondrocytes. Journal of Medical Sciences, 8, 98-101.<br />
Murine Lung Tissue<br />
Zheng,T., Liu,W., Oh,S.Y., Zhu,Z., Hu,B., Homer,R.J., Cohn,L., Grusby,M.J. and Elias,J.A. (2008) IL-13 Receptor α2<br />
Selectively Inhibits IL-13-Induced Responses in the Murine Lung. The Journal of Immunology, 180, 522-529.
Skin<br />
Zheng,T., Oh,M.H., Oh,S.Y., Schroeder,J.T., Glick,A.B. and Zhu,Z. (2008) Transgenic Expression of Interleukin-13 in<br />
the Skin Induces a Pruritic Dermatitis and Skin Remodeling. Journal of Investigative Dermatology,<br />
doi:10.1038/jid.2008.295.<br />
2007<br />
Dermal Fibroblasts<br />
Ahlfors,J.E.W. and Billiar,K.L. (2007) <strong>Bio</strong>mechanical and biochemical characteristics of a human fibroblast-produced<br />
and remodeled matrix. <strong>Bio</strong>materials, 28, 2183-2191.<br />
Murine Vascular and Pulmonary Cells<br />
Ambalavanan,N., LI,P., Bulger,A., Murphy-Ullrich,J., Oparil,S. and Chen,Y.F. (2007) Endothelin-1 Mediates Hypoxia-<br />
Induced Increases in Vascular Collagen in the Newborn Mouse Lung. Pediatr Res, 61, 559-564.<br />
Human Uterine Leiomyomas<br />
Britten,J.L., Malik,M., Payson,M., Norian,J., Joseph,D. and Catherino,W.H. (2007) All-trans retinoic acid regulates<br />
collagen synthesis in human uterine leiomyomas. Fertility and Sterility, 88, 218.<br />
Equine Tendon-Derived Fibrillar Collagen Constructs<br />
Butler,L.M., Metson-Scott,T., Felix,J., Abhyankar,A., Rainger,G.E., Farndale,R.W., Watson,S.P. and Nash,G.B. (2007)<br />
Sequential adhesion of platelets and leukocytes from flowing whole blood onto a collagen-coated surface:<br />
Requirement for a GpVI-binding site in collagen. Thromb Haemost, 97, 814-821.<br />
Rat Lung Tissue<br />
Chen,C.M., Wang,L.F., Chou,H.C., Lang,Y.D. and Lai,Y.P. (2007) Up-regulation of Connective Tissue Growth Factor in<br />
Hyperoxia-Induced Lung Fibrosis. Pediatric Research, 62, 128 – 133.<br />
Murine Osteoblastic MC3T3-E1 Cell Line<br />
Choi,E.M. (2007) Modulatory effects of luteolin on osteoblastic function and inflammatory mediators in osteoblastic<br />
MC3T3-E1 cells. Cell <strong>Bio</strong>logy International, 31, 870-877.<br />
Murine Osteoblastic MC3T3-E1 Cell Line<br />
Choi,E.M. (2007) Apigenin increases osteoblastic differentiation and inhibits tumor necrosis factor-α-induced<br />
production of interleukin-6 and nitric oxide in osteoblastic MC3T3-E1 cells. Pharmazie, 62, 216-220.<br />
Human Mesenchymal Stem Cells<br />
Choi,K.M., Yoon,H.H., Seo,Y.K., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S., Kim,Y.J. and Park,J.K. (2007) Effect of<br />
essential and nonessential amino acid compositions on the in vitro behavior of human mesenchymal stem cells.<br />
Korean Journal of Chemical Engineering, 24, 1058-1063.<br />
Murine Cardiac Fibroblasts<br />
Colston,J.T., de la Rosa,S.D., Koehler,M., Gonzales,K., Mestril,R., Freeman,G.L., Bailey,S.R. and Chandrasekar,B.<br />
(2007) Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor. American Journal of<br />
Physiology- Heart and Circulatory Physiology, 293, H1839.<br />
Rat Hepatic Stellate Cells<br />
Comporti,M., Signorini,C., Arezzini,B., Vecchio,D., Monaco,B. and Gardi,C. (2007) F2-isoprostanes are not just markers<br />
of oxidative stress. Free Radical <strong>Bio</strong>logy and Medicine, 44, 247-256.
Mouse Lung Tissue<br />
Denis,O., van den Brûle,S., Heymans,J., Havaux,X., Rochard,C., Huaux,F. and Huygen,K. (2007) Chronic intranasal<br />
administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyperreactivity<br />
and remodelling. Immunology, 122, 268-278.<br />
Human Colonic Myofibroblasts<br />
Di Sabatino,A., Pender,S.L.F., Jackson,C.L., Prothero,J.D., Gordon,J.N., Picariello,L., Rovedatti,L., Docena,G.,<br />
Monteleone,G. and Rampton,D.S. (2007) Functional Modulation of Crohn’s Disease Myofibroblasts by Anti-Tumor<br />
Necrosis Factor Antibodies. Gastroenterology, 133, 137-149.<br />
Human Dermal Fibroblasts<br />
Digel,I., Kurulgan,E., Linder,P., Kayser,P., Porst,D., Braem,G.J., Zerlin,K., Artmann,G.M. and Artmann,A.T. (2007)<br />
Decrease in extracellular collagen crosslinking after NMR magnetic field application in skin fibroblasts. Medical<br />
and <strong>Bio</strong>logical Engineering and Computing, 45, 91-97.<br />
Murine Muscle Samples<br />
DuBay,D.A., Choi,W., Urbanchek,M.G., Wang,X., Adamson,B., Dennis,R.G., Kuzon Jr,W.M. and Franz,M.G. (2007)<br />
Incisional Herniation Induces Decreased Abdominal Wall Compliance via Oblique Muscle Atrophy and Fibrosis.<br />
Ann Surg, 245, 140-146.<br />
Murine Kidney Samples<br />
El Chaar,M., Chen,J., Seshan,S.V., Jha,S., Richardson,I., Ledbetter,S.R., Vaughan Jr,E.D., Poppas,D.P. and Felsen,D.<br />
(2007) Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral<br />
obstruction. American Journal of Physiology- Renal Physiology, 292, F1291-F1301.<br />
Murine Lung Tissue<br />
Faress,J.A., Nethery,D.E., Kern,E.F.O., Eisenberg,R., Jacono,F.J., Allen,C.L. and Kern,J.A. (2007) Bleomycin Induced<br />
Pulmonary Fibrosis is Attenuated by a Monoclonal Antibody Targeting HER2. Journal of Applied Physiology,<br />
103, 2077-2083.<br />
Murine Colon Samples<br />
Fichtner-Feigl,S., Fuss,I.J., Young,C.A., Watanabe,T., Geissler,E.K., Schlitt,H.J., Kitani,A. and Strober,W. (2007)<br />
Induction of IL-13 Triggers TGF-beta1-Dependent Tissue Fibrosis in Chronic 2, 4, 6-Trinitrobenzene Sulfonic<br />
Acid Colitis. The Journal of Immunology, 178, 5859.<br />
Leporine Mesenchymal Stem Cells<br />
Hannouche,D., Terai,H., Fuchs,J.R., Terada,S., Zand,S., Nasseri,B.A., Petite,H., Sedel,L. and Vacanti,J.P. (2007)<br />
Engineering of implantable cartilaginous structures from bone marrow-derived mesenchymal stem cells. Tissue<br />
Eng. 13, 87-99.<br />
Human Embryonic Stem Cells (hESCs) – Cell Lines H9 and BG01V<br />
Hoben,G.M., Koay,E.J. and Athanasiou,K.A. (2007) Fibrochondrogenesis in Two Embryonic Stem Cell Lines: Effects of<br />
Differentiation Timelines. Stem Cells, 26, 422- 430.<br />
Murine Liver Tissues<br />
Hsu,Y.C., Chiu,Y.T., Cheng,C.C., Wu,C.F., Lin,Y.L. and Huang,Y.T. (2007) Antifibrotic effects of tetrandrine on hepatic<br />
stellate cells and rats with liver fibrosis. Journal of Gastroenterology and Hepatology, 22, 99-111.
Human Primary Keloid Fibroblast Culture Supernatant<br />
Hsu,Y.C., Hsiao,M., Chien,Y.W. and Lee,W.R. (2007) Exogenous nitric oxide stimulated collagen type I expression and<br />
TGF-β1 production in keloid fibroblasts by a cGMP-dependent manner. Nitric Oxide, 16, 258-265.<br />
Murine Pulmonary Lysates, Macrophage Cell Line RAW 264.7 and Human Normal Lung Fibroblast MRC-5 Cell<br />
Line<br />
Hsu,Y.C., Wang,L.F. and Chien,Y.W. (2007) Nitric oxide in the pathogenesis of diffuse pulmonary fibrosis. Free Radical<br />
<strong>Bio</strong>logy and Medicine, 42, 599-607.<br />
Human Primary Fibroblast Culture and Murine Dermal Tissue Samples<br />
Huber,L.C., Distler,J.H., Moritz,F., Hemmatazad,H., Hauser,T., Michel,B.A., Gay,R.E., Matucci-Cerinic,M., Gay,S. and<br />
Distler,O. (2007) Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of<br />
bleomycin-induced skin fibrosis. Arthritis Rheum, 56, 2755-2764.<br />
Murine Bladder Tissue<br />
Imamura,M., Kanematsu,A., Yamamoto,S., Kimura,Y., Kanatani,I., Ito,N., Tabata,Y. and Ogawa,O. (2007) Basic<br />
fibroblast growth factor modulates proliferation and collagen expression in urinary bladder smooth muscle<br />
cells. American Journal of Physiology- Renal Physiology, 293, F1007-F1017.<br />
Dog Cardiovascular Tissue<br />
Jugdutt,B.I., Idikio,H. and Uwiera,R.R.E. (2007) Angiotensin receptor blockade and angiotensin-converting-enzyme<br />
inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing<br />
after reperfused ST-elevation myocardial infarction. Molecular and Cellular <strong>Bio</strong>chemistry, 303, 27-38.<br />
Murine Lung Tissue<br />
Kai,Y., Yoneyama,H., Koyama,J., Hamada,K., Kimura,H. and Matsushima,K. (2007) Treatment with chondroitinase ABC<br />
alleviates bleomycin-induced pulmonary fibrosis. Medical Molecular Morphology, 40, 128-140.<br />
Murine Pancreatic Stellate Cells<br />
Kaku,T., Oono,T., Zhao,H., Gibo,J., Kawabe,K., Ito,T. and Takayanagi,R. (2007) IS-741 Attenuates Local Migration of<br />
Monocytes and Subsequent Pancreatic Fibrosis in Experimental Chronic Pancreatitis Induced by Dibutyltin<br />
Dichloride in Rats. Pancreas, 34, 299-309.<br />
Murine Lung Homogenates<br />
Kang,H.R., Lee,C.G., Homer,R.J. and Elias,J.A. (2007) Semaphorin 7A plays a critical role in TGF-β1-induced pulmonary<br />
fibrosis. J. Exp. Med., 204, 1083.<br />
Murine Lung Tissue<br />
Kang,H.R., Cho,S.J., Lee,C.G., Homer,R.J. and Elias,J.A. (2007) TGF-beta 1 stimulates pulmonary fibrosis and<br />
inflammation via a bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. Journal<br />
of <strong>Bio</strong>logical Chemistry, 282, 7723-7732.<br />
Murine Lung Tissue<br />
Kanno,Y., Kuroki,A., Okada,K., Tomogane,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2007) α2-Antiplasmin is involved<br />
in the production of transforming growth factor β1 and fibrosis. Journal of Thrombosis and Haemostasis, 5,<br />
2266-2273.<br />
Human Stem Cells<br />
Kim,S.G., Jeon,C.H., Suh,H., Choe,J.Y. and Shin,I.H. (2007) P-glycoprotein expression in extracellular matrix formation<br />
of chondrogenic differentiation of human adult stem cells. Cell <strong>Bio</strong>logy International, 31, 1042-1048.
Human Myocardial Samples<br />
Klotz,S., Danser,A.H., Foronjy,R.F., Oz,M.C., Wang,J., Mancini,D., D'Armiento,J. and Burkhoff,D. (2007) The Impact of<br />
Angiotensin-Converting Enzyme Inhibitor Therapy on the Extracellular Collagen Matrix During Left Ventricular<br />
Assist Device Support in Patients With End-Stage Heart Failure. Journal of the American College of Cardiology,<br />
49, 1166.<br />
Murine Lung Tissue<br />
Kohan, M., Bader,R., Puxeddu,I., Levi-Schaffer,F., Breuer,R. and Berkman,N. (2007) Enhanced osteopontin expression<br />
in a murine model of allergen-induced airway remodelling. Clinical & Experimental Allergy, 37, 1444-1454.<br />
Ovine Mesenchymal Progenitor Cells<br />
Kunisaki,S.M., Fuchs,J.R., Steigman,S.A. and Fauza,D.O. (2007) A comparative analysis of cartilage engineered from<br />
different perinatal mesenchymal progenitor cells. Tissue Eng. 13, 2633 – 2644.<br />
Human Fibroblast Cell Lines<br />
Lareu,R.R., Arsianti,I., Subramhanya,H.K., Yanxian,P., Raghunath,M. (2007) In vitro enhancement of collagen matrix<br />
formation and crosslinking for applications in tissue engineering; a preliminary study. Tissue Eng. 13, 385-391.<br />
Murine Cementoblastic Cell Line, OCCM-30<br />
La-Bona,D.A., Tanaka,E., Inubushi,T., Oka,H., Ohta,A., Okada,H., Miyauchi,M., Takata,T. and Tanne,K. (2007)<br />
Cementoblast response to low-and high-intensity ultrasound. Archives of Oral <strong>Bio</strong>logy, 53, 318-323.<br />
Ovine Bone Marrow Mesenchymal Cells<br />
Luo,Z.J. and Seedhom,B.B. (2007) Light and low-frequency pulsatile hydrostatic pressure enhances extracellular matrix<br />
formation by bone marrow mesenchymal cells: an in-vitro study with special reference to cartilage repair.<br />
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 221, 499-<br />
507.<br />
Murine Lung Tissue<br />
Maret,M., Ruffie,C., Periquet,B., Campo,A.M., Menevret,M., Phelep,A., Dziewiszek,K., Druilhe,A. and Pretolani,M.<br />
(2007) Liposomal Retinoic Acids Modulate Asthma Manifestations in Mice. Journal of Nutrition, 137, 2730 –<br />
2736.<br />
Murine Dermal <strong>Bio</strong>psies<br />
Matsushita,T., Fujimoto,M., Hasegawa,M., Matsushita,Y., Komura,K., Ogawa,F., Watanabe,R., Takehara,K. and Sato,S.<br />
(2007) BAFF Antagonist Attenuates the Development of Skin Fibrosis in Tight-Skin Mice. Journal of Investigative<br />
Dermatology, 127, 2772-2780.<br />
Murine Lung Tissue<br />
Mishra,A., Wang,M., Schlotman,J., Nikolaidis,N.M., DeBrosse,C.W., Karow,M.L. and Rothenberg,M.E. (2007) Resistinlike<br />
molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine<br />
lung. American Journal of Physiology- Lung Cellular and Molecular Physiology, 293, L305.<br />
Murine Lung Homogenates<br />
Misson,P., Brombacher,F., Delos,M., Lison,D. and Huaux,F. (2007) Type 2 immune response associated with silicosis is<br />
not instrumental in the development of the disease. American Journal of Physiology- Lung Cellular and<br />
Molecular Physiology, 292, L107-L113.
Murine Bronchoalveolar Lavage Fluid<br />
Morschl,E., Volmer,J.B., Molina,J.G., Lee,J.J., Ochkur,S.I. and Blackburn,M.R. (2007) A3 Adenosine Receptors<br />
Modulate Eosinophil Function In Bleomycin-Induced Lung Injury. The Journal of Allergy and Clinical<br />
Immunology, 119, 218.<br />
Murine Fibroblast NIH3T3 Cell Line<br />
Nishi,Y., Sano,H., Kawashima,T., Okada,T., Kuroda,T., Kikkawa,K., Kawashima,S., Tanabe,M., Goto,T. and<br />
Matsuzawa,Y. (2007) Role of Galectin-3 in Human Pulmonary Fibrosis. Allergology International, 1, 57-65.<br />
Murine Lung Tissue<br />
Niu,N., Le Goff,M.K., Li,F., Rahman,M., Homer,R.J. and Cohn,L. (2007) A Novel Pathway That Regulates Inflammatory<br />
Disease in the Respiratory Tract. The Journal of Immunology, 178, 3846.<br />
Murine Pancreatic Stellate Cells<br />
Nomiyama,Y., Tashiro,M., Yamaguchi,T., Watanabe,S., Taguchi,M., Asaumi,H., Nakamura,H. and Otsuki,M. (2007) High<br />
Glucose Activates Rat Pancreatic Stellate Cells Through Protein Kinase C and p38 Mitogen-Activated Protein<br />
Kinase Pathway. Pancreas, 34, 364-372.<br />
Human Epithelial Cells<br />
Ornatowski,W., Poschet,J.F., Perkett,E., Taylor-Cousar,J.L. and Deretic,V. (2007) Elevated furin levels in human cystic<br />
fibrosis cells result in hypersusceptibility to exotoxin A induced cytotoxicity. Journal of Clinical Investigation,<br />
117, 3489.<br />
Murine Primary Osteoblasts<br />
Orriss,I.R., Utting,J.C., Brandao-Burch,A., Colston,K., Grubb,B.R., Burnstock,G. and Arnett,T.R. (2007) Extracellular<br />
Nucleotides Block Bone Mineralization in Vitro: Evidence for Dual Inhibitory Mechanisms Involving Both P2Y2<br />
Receptors and Pyrophosphate. Endocrinology, 148, 4208.<br />
Murine Pulmonary Tissue<br />
Pena,A.M., Fabre,A., Débarre,D., Marchal-Somme,J., Crestani,B., Martin,J.L., Beaurepaire,E. and Schanne-Klein,M.C.<br />
(2007) Three-dimensional investigation and scoring of extracellular matrix remodeling during lung fibrosis using<br />
multiphoton microscopy. Microsc.Res.Tech. 70, 162 – 170.<br />
Murine Lung Tissue<br />
Pilling,D., Roife,D., Wang,M., Ronkainen,S.D., Crawford,J.R., Travis,E.L. and Gomer,R.H. (2007) Reduction of<br />
Bleomycin-Induced Pulmonary Fibrosis by Serum Amyloid P. The Journal of Immunology, 179, 4035.<br />
Human Primary Fetal and Postnatal Dermal Fibroblasts<br />
Rolfe,K., Grobbelaar,A.O. and Linge,C. (2007) Is TGF-B1 signalling active in fetuses? Journal of Plastic, Reconstructive<br />
& Aesthetic Surgery, 60, S11.<br />
Human Fetal and Postnatal Fibroblasts<br />
Rolfe,K.J., Richardson,J., Vigor,C., Irvine,L.M., Grobbelaar,A.O. and Linge,C. (2007) A Role for TGF-bold italic beta 1-<br />
Induced Cellular Responses during Wound Healing of the Non-Scarring Early Human Fetus? Journal of<br />
Investigative Dermatology, 127, 2656-2667.
Ovine Blood-Derived Endothelial Progenitor Cells<br />
Sales,V.L., Engelmayr Jr,G.C., Johnson Jr,J.A., Gao,J., Wang,Y., Sacks,M.S. and Mayer Jr,J.E. (2007) Protein<br />
Precoating of Elastomeric Tissue-Engineering Scaffolds Increased Cellularity, Enhanced Extracellular Matrix<br />
Protein Production, and Differentially Regulated the Phenotypes of Circulating Endothelial Progenitor Cells.<br />
Circulation, 116, 155-163.<br />
Rat Choloangiocytes<br />
Sato,Y., Harada,K., Ozaki,S., Furubo,S., Kizawa,K., Sanzen,T., Yasoshima,M., Ikeda,H., Sasaki,M. and Nakanuma,Y.<br />
(2007) Cholangiocytes with Mesenchymal Features Contribute to Progressive Hepatic Fibrosis of the Polycystic<br />
Kidney Rat. American Journal of Pathology, 171, 1859 – 1871.<br />
Equine Flexor Digitorum Superficialis Tendon (SDFT) Explants<br />
Schnabel,L.V., Mohammed,H.O., Miller,B.J., McDermott,W.G., Jacobson,M.S., Santangelo,K.S. and Fortier,L.A. (2007)<br />
Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons.<br />
J Orthop Res, 25, 230-240.<br />
Murine Lung Tissue<br />
Shvedova,A.A., Kisin,E.R., Murray,A.R., Gorelik,O., Arepalli,S., Castranova,V., Young,S.H., Gao,F., Tyurina,Y.Y.,<br />
Oury,T.D. and Kagan,V.E. (2007) Vitamin E deficiency enhances pulmonary inflammatory response and<br />
oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice. Toxicology and Applied<br />
Pharmacology, 221, 339-348.<br />
Murine Lung Homogenate<br />
Swain,S.D., Han,S., Harmsen,A., Shampeny,K. and Harmsen,A.G. (2007) Pulmonary Hypertension Can Be a Sequela of<br />
Prior Pneumocystis Pneumonia. American Journal of Pathology, 171, 790-799.<br />
Murine Sponge Implants<br />
Tkalcević,V.I., Cuzić,S., Brajsa,K., Mildner,B., Bokulić,A., Situm,K., Perović,D., Glojnarić,I. and Parnham,M.J. (2007)<br />
Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of<br />
egr-1 expression. European Journal of Pharmacology, 570, 212-221.<br />
Murine Lung Homogenate<br />
Vittal,R., Zhang,H., Han,M.L.K., Moore,B.B., Horowitz,J.C. and Thannickal,V.J. (2007) Effects of the Protein Kinase<br />
Inhibitor, Imatinib Mesylate, on Epithelial/Mesenchymal Phenotypes: Implications for Treatment of Fibrotic<br />
Diseases. Journal of Pharmacology and Experimental Therapeutics, 321, 35-44.<br />
Murine Lung Tissue<br />
Wallach-Dayan,S.B., Golan-Gerstl,R. and Breuer,R. (2007) Evasion of myofibroblasts from immune surveillance: A<br />
mechanism for tissue fibrosis. Proceedings of the National Academy of Sciences, 104, 20460.<br />
Leporine Chondrocyte<br />
Xie,J.U.N., Han,Z., Kim,S.O.O.H., Kim,Y.H.A. and Takehisa Matsuda,P.D. (2007) Mechanical Loading-Dependence of<br />
mRNA Expressions of Extracellular Matrices of Chondrocytes Inoculated into Elastomeric Microporous Poly (Llactide-co-e-caprolactone)<br />
Scaffold. Tissue Engineering, 13, 29-40.<br />
Bovine Decellularised Vocal Fold Lamina and Human Vocal Fold Fibroblast Primary Culture<br />
Xu,C.C., Chan,R.W. and Tirunagari,N. (2007) A <strong>Bio</strong>degradable, Acellular Xenogeneic Scaffold for Regeneration of the<br />
Vocal Fold Lamina Propria. Tissue Engineering, 13, 551-566.
Murine Dermal <strong>Bio</strong>psy<br />
Yamamoto,T., Yokozeki,H. and Nishioka,K. (2007) Fas-and FasL-deficient mice are resistant to the induction of<br />
bleomycin-induced scleroderma. Archives of Dermatological Research, 298, 465-468.<br />
Murine Dermal Tissue<br />
Yoshioka,T., Imura,K., Hikita,I., Hirasawa,T., Sakata,T., Matsutani,T., Horikawa,T. and Arimura,A. (2007) Impact of Tcell<br />
receptor V haplotypes on the development of dermatitis in DS-Nh mice: synergistic production of<br />
interleukin-13 caused by staphylococcal enterotoxin C and peptide glycans from Staphylococcus aureus.<br />
Immunology, 121, 51-61.<br />
2006<br />
Murine Pacreatic Stellate Cells<br />
Asaumi,H., Watanabe,S., Taguchi,M., Tashiro,M., Nagashio,Y., Nomiyama,Y., Nakamura,H. and Otsuki,M. (2006) Green<br />
tea polyphenol (-)-epigallocatechin-3-gallate inhibits ethanol-induced activation of pancreatic stellate cells.<br />
European Journal of Clinical Investigation, 36, 113-122.<br />
Leporine cartilage and Chondrocyte Explants<br />
Baek,Y.H., Huh,J.E., Lee,J.D., Choi,D.Y. and Park,D.S. (2006) Effect of Aralia cordata Extracts on Cartilage Protection<br />
and Apoptosis Inhibition. <strong>Bio</strong>logical & Pharmaceutical Bulletin, 29, 1423-1430.<br />
Porcine Aortic Valves<br />
Balachandran,K., Konduri,S., Sucosky,P., Jo,H. and Yoganathan,A.P. (2006) An Ex Vivo Study of the <strong>Bio</strong>logical<br />
Properties of Porcine Aortic Valves in Response to Circumferential Cyclic Stretch. Annals of <strong>Bio</strong>medical<br />
Engineering, 34, 1655-1665.<br />
Human Articular Chondrocytes<br />
Banu,N., Tsuchiya,T. and Sawada,R. (2006) Effects of a biodegradable polymer synthesized with inorganic tin on the<br />
chondrogenesis of human articular chondrocytes. J <strong>Bio</strong>med Mater Res A. 77, 84-89.<br />
Murine Collagen Deposition on Polypropylene Tapes<br />
Bogusiewicz,M., Wrobel,A., Jankiewicz,K., Adamiak,A., Skorupski,P., Tomaszewski,J. and Rechberger,T. (2006)<br />
Collagen deposition around polypropylene tapes implanted in the rectus fascia of female rats. European<br />
Journal of Obstetrics & Gynecology and Reproductive <strong>Bio</strong>logy, 124, 106-109.<br />
Human Ventricular Tissue Samples<br />
Bruggink,A.H., van Oosterhout,M.F.M., de Jonge,N., Ivangh,B., van Kuik,J., Voorbij,R.H.A.M., Cleutjens,J.P.M.,<br />
Gmelig-Meyling,F.H.J. and de Weger,R.A. (2006) Reverse Remodeling of the Myocardial Extracellular Matrix<br />
After Prolonged Left Ventricular Assist Device Support Follows a Biphasic Pattern. Journal of Heart and Lung<br />
Transplantation, 25, 1091-1098.<br />
Human Dermal Fibroblasts<br />
Chan,E.S.L., Fernandez,P., Merchant,A.A., Montesinos,M.C., Trzaska,S., Desai,A., Tung,C.F., Khoa,D.N., Pillinger,M.H.<br />
and Reiss,A.B. (2006) Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal<br />
fibroblasts and in a murine model of scleroderma. Arthritis & Rheumatism, 54, 2632-2642.<br />
Murine Lung Samples<br />
Cho,S.J., Kang,M.J., Homer,R.J., Kang,H.R., Zhang,X., Lee,P.J., Elias,J.A. and Lee,C.G. (2006) Role of Early Growth<br />
Response-1 (Egr-1) in Interleukin-13-induced Inflammation and Remodeling. Journal of <strong>Bio</strong>logical Chemistry,<br />
281, 8161.
Leporine Articular Cartilage<br />
Cho,Y.J., Huh,J.E., Kim,D.Y., Kim,N.J., Lee,J.D., Baek,Y.H., Cho,E.M., Yang,H.R., Choi,D.Y. and Park,D.S. (2006)<br />
Effect of Betula platyphylla var. japonica on Proteoglycan Release, Type II Collagen Degradation, and Matrix<br />
Metalloproteinase Expression in Rabbit Articular Cartilage Explants. <strong>Bio</strong>logical & Pharmaceutical Bulletin, 29,<br />
1408-1413.<br />
Murine Hepatic Stellate Cells HSC-T6 and Liver Samples<br />
Chong,L.W., Hsu,Y.C., Chiu,Y.T., Yang,K.C. and Huang,Y.T. (2006) Anti-Fibrotic Effects of Thalidomide on Hepatic<br />
Stellate Cells and Dimethylnitrosamine-Intoxicated Rats. Journal of <strong>Bio</strong>medical Science, 13, 403-418.<br />
Murine Liver Tissue<br />
Chou,W-Y., Lu,C-n., Lee,T-h., Wu,C-l., Hung,K-s., Concejero,A.M., Jawan,B. and Wang,C-h. (2006) Electroporative<br />
interleukin-10 gene transfer ameliorates carbon tetrachlo-ride-induced murine liver fibrosis by MMP and TIMP<br />
modulation. Acta Pharmacologica Sinica 27, 469-476.<br />
Murine Bronchial Lavages<br />
Chunn,J.L., Mohsenin,A., Young,H.W.J., Lee,C.G., Elias,J.A., Kellems,R.E. and Blackburn,M.R. (2006) Partially<br />
adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations.<br />
American Journal of Physiology- Lung Cellular and Molecular Physiology, 290, 579-587.<br />
Human Dermal Fibroblasts<br />
Distler,J.H., Jüngel,A., Caretto,D., Schulze-Horsel,U., Kowal-Bielecka,O., Gay,R.E., Michel,B.A., Müller-Ladner,U.,<br />
Kalden,J.R., Gay,S. and Distler,O. (2006) Monocyte chemoattractant protein 1 released from<br />
glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T<br />
cells. Arthritis Rheum, 54, 214-225.<br />
Human Dermal Fibroblasts<br />
Distler,J.H., Jüngel,A., Huber,L.C., Schulze-Horsel,U., Zwerina,J., Gay,R.E., Michel,B.A., Hauser,T., Schett,G. and<br />
Gay,S. (2006) Imatinib mesylate reduces production of extracellular matrix and prevents development of<br />
experimental dermal fibrosis. Arthritis Rheum, 56, 311-322.<br />
Murine Abdominal Wall Samples<br />
DuBay,D.A., Wang,X., Adamson,B., Kuzon,W.M., Dennis,R.G. and Franz,M.G. (2006) Mesh incisional herniorrhaphy<br />
increases abdominal wall elastic properties: A mechanism for decreased hernia recurrences in comparison with<br />
suture repair. Surgery, 140, 14-24.<br />
Human Normal and Keloid Fibroblasts<br />
Duong,H.S., Zhang,Q.Z., Le,A.D., Kelly,A.P., Kamdar,R. and Messadi,D.V. (2006) Elevated prolidase activity in keloids:<br />
correlation with type I collagen turnover. Br J Dermatol 154, 820-828.<br />
Ovine Bone Marrow-Derived Mesenchymal Stem Cells<br />
Engelmayr Jr,G.C., Sales,V.L., Mayer Jr,J.E. and Sacks,M.S. (2006) Cyclic flexure and laminar flow synergistically<br />
accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications for engineered heart<br />
valve tissues. <strong>Bio</strong>materials, 27, 6083-6095.<br />
Murine Lung Samples<br />
Fichtner-Feigl,S., Strober,W., Kawakami,K., Puri,R.K. and Kitani,A. (2006) IL-13 signaling through the IL-13α2 receptor<br />
is involved in induction of TGF-β production and fibrosis. Nature Medicine, 12, 99-106.
Murine Bronchoalveolar Lavage Fluid<br />
Fujimoto, H., Gabazza, E. C., Taguchi, O., Nishii, Y., Nakahara, H., Bruno, N. E., Alessandro-Gabazza, C. N., Kasper,<br />
M., Yano, Y., and Nagashima, M. (2006) Thrombin-Activatable Fibrinolysis Inhibitor Deficiency Attenuates<br />
Bleomycin-Induced Lung Fibrosis. American Journal of Pathology 168, 1086-1096.<br />
Porcine Aortic Smooth Muscle Cells<br />
Gavish,L., Perez,L. and Gertz,S.D. (2006) Low-level laser irradiation modulates matrix metalloproteinase activity and<br />
gene expression in porcine aortic smooth muscle cells. Lasers Surg Med., 38, 779-786.<br />
Porcine Bone Marrow Stromal Cells<br />
Goh,J.C.H., Te Tay,P.D. and Sl Toh,P.D. (2006) Characterization of a Novel Polymeric Scaffold for Potential Application<br />
in Tendon/Ligament Tissue Engineering. Tissue Engineering, 12, 91-99.<br />
Murine Mesangial and Proximal Tubular Cell Culture Supernatants<br />
Han,K.H., Kang,Y.S., Han,S.Y., Jee,Y.H., Lee,M.H., Han,J.Y., Kim,H.K., Kim,Y.S. and Cha,D.R. (2006) Spironolactone<br />
ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats. Kidney<br />
International, 70, 111-120.<br />
Human Kidney-2 Cell Culture Supernatants<br />
Han,S.Y., Jee,Y.H., Han,K.H., Kang,Y.S., Kim,H.K., Han,J.Y., Kim,Y.S. and Cha,D.R. (2006) An imbalance between<br />
matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development<br />
of early diabetic nephropathy. Nephrology Dialysis Transplantation, 21, 2406.<br />
Human Keratinocyte and Fibroblast Artificial Dermis<br />
Harrison,C.A., Gossiel,F., Layton,C.M., Bullock,A.J., Johnson,T., Ubrey Blumsohn,P.D. and Sheila Macneil,P.D. (2006)<br />
Use of an in Vitro Model of Tissue-Engineered Skin to Investigate the Mechanism of Skin Graft Contraction.<br />
Tissue Engineering, 12, 3119-3113.<br />
Leporine Temporomandibular Joint Disc Fibrocartilage, Knee Meniscus Fibrocartilage, Knee Articular<br />
Cartilage and Pubic Symphysis<br />
Hashem,G., Zhang,Q., Hayami,T., Chen,J., Wang,W. and Kapila,S. (2006) Relaxin and β-estradiol modulate targeted<br />
matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss. Arthritis Res<br />
Ther., 8, R98.<br />
Equine Superficial Digital Flexor Tendon in Explant Culture<br />
Haupt,JL., Donnelly,BP. and Nixon,AJ. (2006) Effects of platelet-derived growth factor-BB on the metabolic function<br />
and morphologic features of equine tendon in explants culture. Am J Vet Res, 67, 1595-1600.<br />
Human Osteoblast-Like SaOS-2 Cell Line<br />
Huh,J.E., Yang,H.R., Park,D.S., Choi,D.Y., Baek,Y.H., Cho,E.M., Cho,Y.J., Kang-Il,K., Kim,D.Y. and Lee,J.D. (2006)<br />
Puerariae radix promotes differentiation and mineralization in human osteoblast-like SaOS-2 cells. J<br />
Ethnopharmacol, 104, 345-350.<br />
Murine Pulmonary Myofibroblasts<br />
Izumi,N., Mizuguchi,S., Inagaki,Y., Saika,S., Kawada,N., Nakajima,Y., Inoue,K., Suehiro,S., Friedman,S.L. and Ikeda,K.<br />
(2006) BMP-7 opposes TGF-β1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.<br />
American Journal of Physiology- Lung Cellular and Molecular Physiology, 290, 120-126.
Murine Lung Homogenates<br />
Jacono,F.J., Peng,Y.J., Nethery,D., Faress,J.A., Lee,Z., Kern,J.A. and Prabhakar,N.R. (2006) Acute lung injury<br />
augments hypoxic ventilatory response in the absence of systemic hypoxemia. Journal of Applied Physiology,<br />
101, 1795.<br />
Human Gingival Fibroblasts<br />
Kato,T., Okahashi,N., Ohno,T., Inaba,H., Kawai,S. and Amano,A. (2006) Effect of phenytoin on collagen accumulation<br />
by human gingival fibroblasts exposed to TNF-ain vitro. Oral Diseases, 12, 156-162.<br />
Human Alveolar Epithelial (A549) and Akata Cell Lines<br />
Keating,D.T., Sadlier,D.M., Patricelli,A., Smith,S.M., Walls,D., Egan,J.J. and Doran,P.P. (2006) Microarray identifies<br />
ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells. Respiratory Research, 7,<br />
114.<br />
Murine Kidneys<br />
Kellner,D., Chen,J., Richardson,I., Seshan,S.V., EL Chaar,M., Vaughan Jr,E.D., Poppas,D. and Felsen,D. (2006)<br />
Angiotensin receptor blockade decreases fibrosis and fibroblast expression in a rat model of unilateral ureteral<br />
obstruction. J Urol, 176, 806-812.<br />
Murine Kidney Cortex<br />
Kushibiki,T., Nagata-Nakajima,N., Sugai,M., Shimizu,A. and Tabata,Y. (2006) Enhanced anti-fibrotic activity of plasmid<br />
DNA expressing small interference RNA for TGF-beta type II receptor for a mouse model of obstructive<br />
nephropathy by cationized gelatin prepared from different amine compounds. J Control Release, 110, 610-<br />
617.<br />
Murine Tracheal Homogenates<br />
Lama,V.N., Harada,H., Badri,L.N., Flint,A., Hogaboam,C.M., McKenzie,A., Martinez,F.J., Toews,G.B., Moore,B.B. and<br />
Pinsky,D.J. (2006) Obligatory Role for Interleukin-13 in Obstructive Lesion Development in Airway Allografts.<br />
American Journal of Pathology, 169, 47.<br />
Human ER-Positive Breast Cancer MCF-7 Cell Line and Murine Osteoblast-Like MC3T3-E1 Cell Line<br />
Lee,K.H. and Choi,E.M. (2006) Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on<br />
the function of osteoblastic MC3T3-E1 cells. Phytother.Res, 20, 952-960.<br />
Murine Osteoblast-Like MC3T3-E1 Cell Line<br />
Lee,K.H. and Choi,E.M. (2006) Rubus coreanus Miq. Extract Promotes Osteoblast Differentiation and Inhibits Bone-<br />
Resorbing Mediators in MC3T3-E1 Cells. The American Journal of Chinese Medicine, 34, 643-654.<br />
Murine Lung Homogenate<br />
Lee,K.S., Park,S.J., Kim,S.R., Min,K.H., Jin,S.M., Lee,H.K. and Lee,Y.C. (2006) Modulation of Airway Remodeling and<br />
Airway Inflammation by Peroxisome Proliferator-Activated Receptor γ in a Murine Model of Toluene<br />
Diisocyanate-Induced Asthma. The Journal of Immunology, 177, 5248.<br />
Murine Liver Tissue<br />
Lee,T.H., Jawan,B., Chou,W.Y., Lu,C.N., Wu,C.L., Kuo,H.M., Concejero,A.M. and Wang,C.H. (2006) alpha-Melanocytestimulating<br />
hormone gene therapy reverses carbon tetrachloride induced liver fibrosis in mice. J Gene Med, 8,<br />
764-772.
Human Dermal Fibroblasts<br />
Lee,J.H., Roh,M.R. and Lee,K.H. (2006) Effects of Infrared Radiation on Skin Photo-Aging and Pigmentation. Yonsei<br />
Med J., 47, 485-490.<br />
Murine Bone Marrow Stromal Cells and Osteoblasts<br />
Leivo,J., Meretoja,V., Vippola,M., Levanen,E., Vallittu,P. and Mantyla,T.A. (2006) Sol-gel derived aluminosilicate<br />
coatings on alumina as substrate for osteoblasts. Acta <strong>Bio</strong>mater. 2, 659-668.<br />
Human Skin Fibroblasts<br />
Li,B., Chen,J. and James,H.C.W. (2006) RGD peptide-conjugated poly (dimethylsiloxane) promotes adhesion,<br />
proliferation, and collagen secretion of human fibroblasts. Mater Res, 79, 989-998.<br />
Murine Cardiac Fibroblasts<br />
Lijnen,P., Papparella,I., Petrov,V., Semplicini,A. and Fagard,R. (2006) Angiotensin II-stimulated collagen production in<br />
cardiac fibroblasts is mediated by reactive oxygen species. J Hypertens, 24, 757-766.<br />
Murine Hepatocytes and Hepatic Stellate Cells<br />
Lin,Y.L., Wu,C.H., Luo,M.H., Huang,Y.J., Wang,C.N., Shiao,M.S. and Huang,Y.T. (2006) In vitro protective effects of<br />
salvianolic acid B on primary hepatocytes and hepatic stellate cells. Journal of Ethnopharmacology, 105, 215-<br />
222.<br />
Murine Lung Tissue<br />
Liu,H., Liu,L., Fletcher,B.S. and Visner,G.A. (2006) Sleeping Beauty-based gene therapy with indoleamine 2, 3dioxygenase<br />
inhibits lung allograft fibrosis. The FASEB Journal, 20, 2384.<br />
Murine Lung Tissue<br />
Lopez,E., del Pozo,V., Miguel,T., Sastre,B., Seoane,C., Civantos,E., Llanes,E., Baeza,M.L., Palomino,P. and Cardaba,B.<br />
(2006) Inhibition of Chronic Airway Inflammation and Remodeling by Galectin-3 Gene Therapy in a Murine<br />
Model 1. The Journal of Immunology, 176, 1943-1950.<br />
Murine Lung Tissue<br />
Ma,B., Blackburn,M.R., Lee,C.G., Homer,R.J., Liu,W., Flavell,R.A., Boyden,L., Lifton,R.P., Sun,C.X. and Young,H.W.<br />
(2006) Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis.<br />
Journal of Clinical Investigation, 116, 1274-1283.<br />
Human Dermal Fibroblast Primary and CRL-2127 Cell Cultures<br />
Makareeva,E., Cabral,W.A., Marini,J.C. and Leikin,S. (2006) Molecular Mechanism of Alpha 1(I)-Osteogenesis<br />
Imperfecta/Ehlers-Danlos Syndrome: Unfolding of an N-Anchor Domain at the N-Terminal End of the Type I<br />
Collagen Triple Helix. Journal of <strong>Bio</strong>logical Chemistry, 281, 6463.<br />
Murine Lung Tissue<br />
Manoury,B., Nenan,S., Guenon,I., Boichot,E., Planquois,J.M., Bertrand,C.P. and Lagente,V. (2006) Macrophage<br />
metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice. J Inflamm<br />
(Lond), 3, 2.<br />
Murine Dermal Tissue<br />
McFarlin,K., Gao,X., Liu,Y.B., Dulchavsky,D.S., Kwon,D., Arbab,A.S., Bansal,M., Li,Y., Chopp,M. and Dulchavsky,S.A.<br />
(2006) Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat. Wound Repair<br />
and Regeneration, 14, 471-478.
Leporine Bone Marrow-Derived Mesenchymal Stem Cells<br />
Medrado,G.C.B., Machado,C.B., Valerio,P., Sanches,M.D. and Goes,A.M. (2006) The effect of a chitosan-gelatin matrix<br />
and dexamethasone on the behavior of rabbit mesenchymal stem cells. <strong>Bio</strong>medical Materials, 1, 155-161.<br />
Murine Rectal Tissue<br />
Motomura,Y., Khan,W.I., El-Sharkawy,R.T., Verma-Gandhu,M., Verdu,E.F., Gauldie,J. and Collins,S.M. (2006) Induction<br />
of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1. Gut, 55,<br />
662-670.<br />
Human Lung Fibroblastic Cell Line TIG-3-20<br />
Nagano, J., Iyonaga, K., Kawamura, K., Yamashita, A., Ichiyasu, H., Okamoto, T., Suga, M., Sasaki, Y., and Kohrogi, H.<br />
(2006) Use of tacrolimus, a potent antifibrotic agent, in bleomycin-induced lung fibrosis. European Respiratory<br />
Journal, 27, 460-469.<br />
Murine Osteoblast-Like MC3T3-E1 Cell Line<br />
Narita,Y., Nomura,J., Ohta,S., Inoh,Y., Suzuki,K.M., Araki,Y., Okada,S., Matsumoto,I., Isohama,Y. and Abe,K. (2006)<br />
Royal Jelly Stimulates Bone Formation: Physiologic and Nutrigenomic Studies with Mice and Cell Lines.<br />
<strong>Bio</strong>science, <strong>Bio</strong>technology, and <strong>Bio</strong>chemistry, 70, 2508-2514.<br />
Murine Lung Tissue<br />
Oikonomou,N., Harokopos,V., Zalevsky,J., Valavanis,C., Kotanidou,A., Szymkowski,D.E., Kollias,G. and Aidinis,V.<br />
(2006) Soluble TNF Mediates the Transition from Pulmonary Inflammation to Fibrosis. PLoS ONE, 1, e108.<br />
Murine Osteoblast Primay Cultures<br />
Oktar,F.N., Valério,P., Goller,G., Agathopoulos,S., Goes,A.M. and Leite,M.F. (2006) <strong>Bio</strong>compatibility of the Outer<br />
Prismatic and the Inner Nacreous Layers of Four Different Molluscs. Key Engineering Materials, 309, 449.<br />
Human Ligament Fibroblasts Primary Culture<br />
Park,S.A., Kim,I.A., Lee,Y.J., Shin,J.W., Kim,C.R., Kim,J.K., Yang,Y.I. and Shin,J.W. (2006) <strong>Bio</strong>logical Responses of<br />
Ligament Fibroblasts and Gene Expression Profiling on Micropatterned Silicone Substrates Subjected to<br />
Mechanical Stimuli. Journal of <strong>Bio</strong>science and <strong>Bio</strong>engineering, 102, 402-412.<br />
Murine Hepatic Stellate Cells<br />
Patella,S., Phillips,D.J., Tchongue,J., de Kretser,D.M. and Sievert,W. (2006) Follistatin attenuates early liver fibrosis:<br />
effects on hepatic stellate cell activation and hepatocyte apoptosis. American Journal of Physiology-<br />
Gastrointestinal and Liver Physiology, 290, 137-144.<br />
Human Fibroblast HFL-1 and Epithelial A549 Cell Line Co-Cultures<br />
Phillips,R.J., Blatt,L.M. and Ozes,O.N. (2006) Pirfenidone and Interferon Gamma-1b Inhibit the Profibrotic Effects of<br />
Osteopontin. Chest, 130, 229S.<br />
Murine Lung Tissue<br />
Polte,T., Foell,J., Werner,C., Hoymann,H.G., Braun,A., Burdach,S., Mittler,R.S. and Hansen,G. (2006) CD137-mediated<br />
immunotherapy for allergic asthma. Journal of Clinical Investigation, 116, 1025-1036.<br />
Human Mesenchymal Populations and Articular Chondrocytes<br />
Pound,J.C., Green,D.W., Chaudhuri,J.B., Mann,S., Roach,H.I. and Oreffo,R.O.C. (2006) Strategies to Promote<br />
Chondrogenesis and Osteogenesis from Human Bone Marrow Cells and Articular Chondrocytes Encapsulated in<br />
Polysaccharide Templates. Tissue Engineerig, 12, 2789-2799.
Murine Cardiac Tissue<br />
Reyes,M., Steinhelper,M.E., Alvarez,J.A., Escobedo,D., Pearce,J., Valvano,J.W., Pollock,B.H., Wei,C.L., Kottam,A. and<br />
Altman,D. (2006) Impact of physiological variables and genetic background on myocardial frequency-resistivity<br />
relations in the intact beating murine heart. American Journal of Physiology- Heart and Circulatory Physiology,<br />
291, H1659.<br />
Murine Fibroblast and Macrophage Co-Cultures<br />
Saika, S., Ikeda, K., Yamanaka, O., Flanders, K. C., Okada, Y., Miyamoto, T., Kitano, A., Ooshima, A., Nakajima, Y.,<br />
and Ohnishi, Y. (2006) Loss of Tumor Necrosis Factor α Potentiates Transforming Growth Factor β-mediated<br />
Pathogenic Tissue Response During Wound Healing. American Journal of Pathology 168, 1848-1860.<br />
Ovine Blood-Derived Endothelial Progenitor Cells<br />
Sales,V.L., Engelmayr Jr,G.C., Mettler,B.A., Johnson Jr,J.A., Sacks,M.S. and Mayer Jr,J.E. (2006) Transforming Growth<br />
Factor-β1 Modulates Extracellular Matrix Production, Proliferation, and Apoptosis of Endothelial Progenitor<br />
Cells in Tissue-Engineering Scaffolds. Circulation, 114, 1193-1199.<br />
Murine Liver Tissue<br />
Sato,Y., Harada,K., Furubo,S., Kizawa,K., Sanzen,T., Yasoshima,M., Ozaki,S., Isse,K., Sasaki,M. and Nakanuma,Y.<br />
(2006) Inhibition of Intrahepatic Bile Duct Dilation of the Polycystic Kidney Rat with a Novel Tyrosine Kinase<br />
Inhibitor Gefitinib. American Journal of Pathology, 169, 1238.<br />
Porcine Cardiac Valve Leaflets<br />
Schenke-Layland, K., Madershahian, N., Riemann, I., Starcher, B., Halbhuber, K. J., Konig, K., and Stock, U. A. Impact<br />
of Cryopreservation on Extracellular Matrix Structures of Heart Valve Leaflets. The Annals of Thoracic Surgery<br />
81, 918-926.<br />
Human Primary Fibroblast Cultures from Scleroderma Patients<br />
Sherriff-Tadano,R., Ohta,A., Morito,F., Mitamura,M., Haruta,Y., Koarada,S., Tada,Y., Nagasawa,K. and Ozaki,I. (2006)<br />
Antifibrotic effects of hepatocyte growth factor on scleroderma fibroblasts and analysis of its mechanism.<br />
Modern Rheumatology, 16, 364-371.<br />
Murine Lung Tissue<br />
Shim,Y.M., Zhu,Z., Zheng,T., Lee,C.G., Homer,R.J., Ma,B. and Elias,J.A. (2006) Role of 5-Lipoxygenase in IL-13-<br />
Induced Pulmonary Inflammation and Remodeling. The Journal of Immunology, 177, 1918.<br />
Porcine Heart Valves<br />
Stock,U.A., Degenkolbe,I., Attmann,T., Schenke-Layland,K., Freitag,S. and Lutter,G. (2006) Prevention of devicerelated<br />
tissue damage during percutaneous deployment of tissue-engineered heart valves. The Journal of<br />
Thoracic and Cardiovascular Surgery, 131, 1323-1330.<br />
Murine Lung Tissue and Bronchoalveolar Lavage Fluid<br />
Sun,C.X., Zhong,H., Mohsenin,A., Morschl,E., Chunn,J.L., Molina,J.G., Belardinelli,L., Zeng,D. and Blackburn,M.R.<br />
(2006) Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury.<br />
Journal of Clinical Investigation, 116, 2173-2182.<br />
Human Tendon Fibroblasts<br />
Talwalkar,S.C., Evans,C.E., Trail,I.A. and McGrouther,D.A. (2006) Does Anatomical Location of a Tendon (Hand or<br />
Forearm) Influences Fibroblast Function in the Presence of Physical Forces. Journal of Bone and Joint Surgery –<br />
British Volume 88-B Supp. III:411.
Murine Lung Homogenate<br />
Volmer,J.B., Thompson,L.F. and Blackburn,M.R. (2006) Ecto-5'-Nucleotidase (CD73)-Mediated Adenosine Production Is<br />
Tissue Protective in a Model of Bleomycin-Induced Lung Injury. The Journal of Immunology, 176, 4449-4458.<br />
Murine Liver Tissue<br />
Wang,C.H., Lee,T.H., Lu,C.N., Chou,W.Y., Hung,K.S., Concejero,A.M. and Jawan,B. (2006) Electroporative alpha-MSH<br />
gene transfer attenuates thioacetamide-induced murine hepatic fibrosis by MMP and TIMP modulation. Gene<br />
Therapy, 13, 1000-1009.<br />
Bovine Annulus Fibrosus Primary Cell Culture<br />
Wilda,H. and Gough,J.E. (2006) In vitro studies of annulus fibrosus disc cell attachment, differentiation and matrix<br />
production on PDLLA/45S5 <strong>Bio</strong>glass composite films. <strong>Bio</strong>materials, 27, 5220-5229.<br />
Murine Dermal <strong>Bio</strong>psy<br />
Wu,G.L.D.M. and Varga,J. (2006) Increased Bleomycin-Induced Skin Fibrosis in Mice Lacking the Th1-Specific<br />
Transcription Factor T-bet. Pathobiology, 73, 224-237.<br />
Murine Dermal Tissue<br />
Yasuoka,H., Jukic,D.M., Zhou,Z., Choi,A.M. and Feghali-Bostwick,C.A. (2006) Insulin-like growth factor binding protein<br />
5 induces skin fibrosis: A novel murine model for dermal fibrosis. Arthritis Rheum, 54, 3001-3010.<br />
2005<br />
Murine Lung Explant<br />
Aono,Y., Nishioka,Y., Inayama,M., Ugai,M., Kishi,J., Uehara,H., Izumi,K. and Sone,S. (2005) Imatinib as a Novel<br />
Antifibrotic Agent in Bleomycin-induced Pulmonary Fibrosis in Mice. American Journal of Respiratory and<br />
Critical Care Medicine, 171, 1279.<br />
Murine Lung Explants<br />
Azuma,A., Li,Y.J., Abe,S., Usuki,J., Matsuda,K., Henmi,S., Miyauchi,Y., Ueda,K., Izawa,A. and Sone,S. (2005)<br />
Interferon-β Inhibits Bleomycin-Induced Lung Fibrosis by Decreasing Transforming Growth Factor-β and<br />
Thrombospondin. American Journal of Respiratory Cell and Molecular <strong>Bio</strong>logy, 32, 93-98.<br />
Murine Lung Explants<br />
Barbarin,V., Xing,Z., Delos,M., Lison,D. and Huaux,F. (2005) Pulmonary overexpression of IL-10 augments lung fibrosis<br />
and Th2 responses induced by silica particles. American Journal of Physiology- Lung Cellular and Molecular<br />
Physiology, 288, 841-848.<br />
Murine Lung Explants<br />
Beamer,C.A. and Holian,A. (2005) Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis<br />
following silica exposure. American Journal of Physiology- Lung Cellular and Molecular Physiology, 289, 186-<br />
195.<br />
Murine Lung Homogenates<br />
Burdick,M.D., Murray,L.A., Keane,M.P., Xue,Y.Y., Zisman,D.A., Belperio,J.A. and Strieter,R.M. (2005) CXCL11<br />
Attenuates Bleomycin-induced Pulmonary Fibrosis via Inhibition of Vascular Remodeling. American Journal of<br />
Respiratory and Critical Care Medicine, 171, 261.
Human Fibroblasts<br />
Cabral,W.A., Makareeva,E., Colige,A., Letocha,A.D., Ty,J.M., Yeowell,H.N., Pals,G., Leikin,S. and Marini,J.C. (2005)<br />
Mutations Near Amino End of alpha 1(I) Collagen Cause Combined Osteogenesis Imperfecta/Ehlers-Danlos<br />
Syndrome by Interference with N-propeptide Processing. Journal of <strong>Bio</strong>logical Chemistry, 280, 19259-19269.<br />
Human to Mouse Cardiac Allografts<br />
Campbell,L.G., Ramachandran,S., Liu,W., Shipley,J.M., Itohara,S., Rogers,J.G., Moazami,N., Senior,R.M. and<br />
Jaramillo,A. (2005) Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the<br />
pathogenesis of cardiac allograft rejection. Am J Transplant, 5, 517-528.<br />
Human Dental Pulp Cells<br />
Chan,C.P., Lan,W.H., Chang,M.C., Chen,Y.J., Lan,W.C., Chang,H.H. and Jeng,J.H. (2005) Effects of TGF-βs on the<br />
growth, collagen synthesis and collagen lattice contraction of human dental pulp fibroblasts in vitro. Archives<br />
of Oral <strong>Bio</strong>logy, 50, 469-479.<br />
Murine Lung Homogenate<br />
Chen,Q., Rabach,L., Noble,P., Zheng,T., Lee,C.G., Homer,R.J. and Elias,J.A. (2005) IL-11 Receptor a in the<br />
Pathogenesis of IL-13-Induced Inflammation and Remodeling 1. The Journal of Immunology, 174, 2305-2313.<br />
Human Periodontal Fibroblasts<br />
Chen,Y.J., Jeng,J.H., Jane Yao,C.C., Chen,M.H., Hou,L.T. and Lan,W.H. (2005) Long-term effect of pulsed Nd: YAG<br />
laser irradiation on cultured human periodontal fibroblasts. Lasers in Surgery and Medicine, 36, 225-233.<br />
Murine Osteoblastic MC3T3-E1 Cell Line<br />
Choi,E.M. (2005) The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells.<br />
<strong>Bio</strong>chem Pharmacol, 70, 363-368.<br />
Murine Lung Homogenates<br />
Chunn,J.L., Molina,J.G., Mi,T., Xia,Y., Kellems,R.E. and Blackburn,M.R. (2005) Adenosine-Dependent Pulmonary<br />
Fibrosis in Adenosine Deaminase-Deficient Mice 1. The Journal of Immunology, 175, 1937-1946.<br />
Murine Hepatic Stellate Cells<br />
Comporti,M., Arezzini,B., Signorini,C., Sgherri,C., Monaco,B. and Gardi,C. (2005) F2-isoprostanes stimulate collagen<br />
synthesis in activated hepatic stellate cells: a link with liver fibrosis?’ Laboratory Investigation, 85, 1381-1391.<br />
Equine Tendons<br />
Dahlgren,L., Mohammed,H. and Nixon,A. (2005) Temporal expression of growth factors and matrix molecules in healing<br />
tendon lesions. Journal of Orthopaedic Research, 23, 84-92.<br />
Murine Thrombi<br />
Deatrick,K.B., Eliason,J.L., Lynch,E.M., Moore,A.J., Dewyer,N.A., Varma,M.R., Pearce,C.G., Upchurch,G.R.,<br />
Wakefield,T.W. and Henke,P.K. (2005) Vein wall remodeling after deep vein thrombosis involves matrix<br />
metalloproteinases and late fibrosis in a mouse model. J Vasc Surg, 42, 140-148.<br />
Murine Abdominal Wall Samples<br />
DuBay,D.A., Wang,X., Adamson,B., Kuzon,W.M., Dennis,R.G. and FRANZ,M.G. (2005) Progressive fascial wound failure<br />
impairs subsequent abdominal wall repairs: A new animal model of incisional hernia formation. Surgery, 137,<br />
463-471.
Simian Renal Fibroblasts (NRK-49F)<br />
El Chaar,M., Attia,E., Chen,J., Hannafin,J., Poppas,D.P. and Felsen,D. (2005) Cyclooxygenase-2 Inhibitor Decreases<br />
Extracellular Matrix Synthesis in Stretched Renal Fibroblasts. Nephron Exp Nephrol, 100, 150-155.<br />
Ovine Vascular Smooth Muscle Cells<br />
Engelmayr,G.C., Mayer,J.E., Rabkin,E., Sacks,M.S., Schoen,F.J. and Sutherland,F.W.H. (2005) The independent role of<br />
cyclic flexure in the early in vitro development of an engineered heart valve tissue. <strong>Bio</strong>materials, 26, 175-187.<br />
Murine Colon Homogenate<br />
Fichtner-Feigl,S., Fuss,I.J., Preiss,J.C., Strober,W. and Kitani,A. (2005) Treatment of murine Th1-and Th2-mediated<br />
inflammatory bowel disease with NF-κB decoy oligonucleotides. Journal of Clinical Investigation, 115, 3057-<br />
3071.<br />
Ovine Mesenchymal Progenitor Cells and Fetal Chondrocytes<br />
Fuchs, J. R., Hannouche, D., Terada, S., Zand, S., Vacanti, J. P., and Fauza, D. O. (2005) Cartilage Engineering from<br />
Ovine Umbilical Cord Blood Mesenchymal Progenitor Cells. Stem Cells 23, 958-964.<br />
Murine Fibroblasts and Mesenchymal Stem Cells<br />
Ge,Z., Goh,J.C.H. and Lee,E.H. (2005) Selection of Cell Source for Ligament Tissue Engineering. Cell Transplantation,<br />
14, 573-583.<br />
Murine Lung <strong>Bio</strong>psies<br />
Genovese,T., Cuzzocrea,S., Di Paola,R., Failla,M., Mazzon,E., Sortino,M.A., Frasca,G., Gili,E., Crimi,N. and Caputi,A.P.<br />
(2005) Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung<br />
injury. Respir Res, 6, 58.<br />
Porcine Anterior Cruciate Ligaments<br />
Harrison,R.D. (2005) Effect of Extraction Protocols and Epidermal Growth Factor on the Cellular Repopulaton of<br />
Decellularized Anterior Cruciate Ligament Allografts. <strong>Bio</strong>med Mater Res A,75, 841-854.<br />
Murine Hepatic Stellate cells (HSC-T6) and Liver Samples<br />
Hsu,Y.C., Lin,Y.L., Chiu,Y.T., Shiao,M.S., Lee,C.Y. and Huang,Y.T. (2005) Antifibrotic effects of Salvia miltiorrhiza on<br />
dimethylnitrosamine-intoxicated rats. Journal of <strong>Bio</strong>medical Science, 12, 185-195.<br />
Rat Left Ventricle<br />
Iwata,K., Sawa,Y., Kitagawa-Sakakida,S., Kawaguchi,N., Matsuura,N., Nakamura,T. and Matsuda,H. (2005) Gene<br />
transfection of hepatocyte growth factor attenuates the progression of cardiac remodeling in the<br />
hypertrophied heart. The Journal of Thoracic and Cardiovascular Surgery, 130, 719-725.<br />
Human Gingival Fibroblasts<br />
Kato,T., Okahashi,N., Kawai,S., Kato,T., Inaba,H., Morisaki,I. and Amano,A. (2005) Impaired Degradation of Matrix<br />
Collagen in Human Gingival Fibroblasts by the Antiepileptic Drug Phenytoin. J Periodontol, 76, 941-950.<br />
Human Periodontal Ligament Cell Cultures<br />
Kawase,T., Okuda,K., Saito,Y. and Yoshie,H. (2005) In vitro evidence that the biological effects of platelet-rich plasma<br />
on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-beta or<br />
platelet-derived growth factor. J Periodontol, 76, 760-767.
Cadaveric Human Lumbar Intervertebral Discs<br />
Keshari,K.R., Lotz,J.C., Kurhanewicz,J. and Majumdar,S. (2005) Correlation of HR-MAS Spectroscopy Derived<br />
Metabolite Concentrations With Collagen and Proteoglycan Levels and Thompson Grade in the Degenerative<br />
Disc. Spine, 30, 2683-2688.<br />
Human Myocardial Samples<br />
Klotz, S., Foronjy, R. F., Dickstein, M. L., Gu, A., Garrelds, I. M., Jan Danser, A. H., Oz, M. C., D'Armiento, J., and<br />
Burkhoff, D. (2005) Mechanical Unloading During Left Ventricular Assist Device Support Increases Left<br />
Ventricular Collagen Cross-Linking and Myocardial Stiffness. Circulation 112, 364-374.<br />
Porcine Aortic Valves in Culture<br />
Konduri,S., Xing,Y., Warnock,J.N., He,Z. and Yoganathan,A.P. (2005) Normal Physiological Conditions Maintain the<br />
<strong>Bio</strong>logical Characteristics of Porcine Aortic Heart Valves: An Ex Vivo Organ Culture Study. Annals of <strong>Bio</strong>medical<br />
Engineering, 33, 1158-1166.<br />
Murine Kidney Cortex<br />
Kushibiki,T., Nagata-Nakajima,N., Sugai,M., Shimizu,A. and Tabata,Y. (2005) Delivery of plasmid DNA expressing small<br />
interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis. J<br />
Control Release, 105, 318-331.<br />
Murine Dermal Fibroblasts<br />
Lateef,H., Aslam,M.N., Stevens,M.J. and Varani,J. (2005) Pretreatment of diabetic rats with lipoic acid improves<br />
healing of subsequently-induced abrasion wounds. Archives of Dermatological Research, 297, 75-83.<br />
Murine Granulomas<br />
Layland,L.E., Wagner,H. and Prazeres da Costa,C. (2005) Lack of antigen-specific Th1 response alters granuloma<br />
formation and composition in Schistosoma mansoni-infected MyD88-/-mice. Eur.J.Immunol, 35, 3248-3257.<br />
Human Ligament Fibroblasts<br />
Lee,C.H., Shin,H.J., Cho,I.H., Kang,Y.M., Kim,I.A., Park,K.D. and Shin,J.W. (2005) Nanofiber alignment and direction<br />
of mechanical strain affect the ECM production of human ACL fibroblast. <strong>Bio</strong>materials, 26, 1261-1270.<br />
Murine Osteoblast-Like MC3T3-E1 Cell Line<br />
Lee,K.H. and Choi,E.M. (2005) <strong>Bio</strong>chanin A Stimulates Osteoblastic Differentiation and Inhibits Hydrogen Peroxide-<br />
Induced Production of Inflammatory Mediators in MC3T3-E1 Cells. <strong>Bio</strong>logical & Pharmaceutical Bulletin, 28,<br />
1948-1953.<br />
Murine Lung Tissue Supernatant<br />
Liu,H., Drew,P., Gaugler,A.C., Cheng,Y. and Visner,G.A. (2005) Pirfenidone inhibits lung allograft fibrosis through Larginine-arginase<br />
pathway. Am J Transplant, 5, 1256-1263.<br />
Murine Dermal <strong>Bio</strong>psies<br />
Matsushita,M., Yamamoto,T. and Nishioka,K. (2005) Plasminogen activator inhibitor-1 is elevated, but not essential, in<br />
the development of bleomycin-induced murine scleroderma. Clinical and Experimental Immunology, 139, 429-<br />
438.<br />
Human Venous Myofibroblasts<br />
Mol,A., van Lieshout,M.I., Dam-de Veen,C.G., Neuenschwander,S., Hoerstrup,S.P., Baaijens,F.P. and Bouten,C.V.C.<br />
(2005) Fibrin as a cell carrier in cardiovascular tissue engineering applications. <strong>Bio</strong>materials, 26, 3113-3121.
Murine Lung Homogenate<br />
Moore,B.B., Ballinger,M.N., White,E.S., Green,M.E., Herrygers,A.B., Wilke,C.A., Toews,G.B. and Peters-Golden,M.<br />
(2005) Bleomycin-Induced E Prostanoid Receptor Changes Alter Fibroblast Responses to Prostaglandin E2 1. The<br />
Journal of Immunology, 174, 5644-5649.<br />
Cricetine Left Ventricles<br />
Nakamura,T., Matsumoto,K., Mizuno,S., Sawa,Y., Matsuda,H. and Nakamura,T. (2005) Hepatocyte growth factor<br />
prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts. American Journal of<br />
Physiology- Heart and Circulatory Physiology, 288, 2131-2139.<br />
Human Lung Fibroblast Culture Supernatants<br />
Nakoman,C., Resmi,H., Ay,O., Acikel,U., Atabey,N. and Güner,G. (2005) Effects of basic fibroblast factor (bFGF) on<br />
MMP-2, TIMP-2, and type-I collagen levels in human lung carcinoma fibroblasts. <strong>Bio</strong>chimie, 87, 343-351.<br />
Leporine Temporomandibular Joint Discs<br />
Naqvi,T., Duong,T.T., Hashem,G., Shiga,M., Zhang,Q. and Kapila,S. (2005) Relaxin's induction of metalloproteinases is<br />
associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants.<br />
Arthritis Res Ther, 7, R1-11.<br />
Murine Lung Homogenate<br />
Nethery,D.E., Moore,B.B., Minowada,G., Carroll,J., Faress,J.A. and Kern,J.A. (2005) Expression of mutant human<br />
epidermal receptor 3 attenuates lung fibrosis and improves survival in mice. Journal of Applied Physiology, 99,<br />
298-307.<br />
Human Atheromatous Plaques<br />
Penz, S., Reininger, A. J., Brandl, R., Goyal, P., Rabie, T., Bernlochner, I., Rother, E., Goetz, C., Engelmann, B., and<br />
Smethurst, P. A. (2005) Human atheromatous plaques stimulate thrombus formation by activating platelet<br />
glycoprotein VI. The FASEB Journal 19, 898-909. 2005.<br />
Porcine Chordae Tendineae<br />
Ritchie, J., Warnock, J. N., and Yoganathan, A. P. (2005) Structural Characterization of the Chordae Tendineae in<br />
Native Porcine Mitral Valves. The Annals of Thoracic Surgery 80, 189-197.<br />
Murine Osteoblast Primary Cultures<br />
Sampaio,B.V., Göller,G., Oktar,F.N., Val rio,P., Goes,A.M. and Leite,M.F. (2005) <strong>Bio</strong>compatibility Evaluation of Three<br />
Different Titanium-Hydroxyapatite Composites. Key Eng.Mater, 284, 639-642.<br />
Murine Dermal <strong>Bio</strong>psies<br />
Santiago,B., Gutierrez-Cañas,I., Dotor,J., Palao,G., Lasarte,J.J., Ruiz,J., Prieto,J., Borrbs-Cuesta,F., Pablos,J.L. and<br />
<strong>Bio</strong>tech,D. (2005) Topical Application of a Peptide Inhibitor of Transforming Growth Factor-bold beta 1<br />
Ameliorates Bleomycin-Induced Skin Fibrosis. Journal of Investigative Dermatology, 125, 450-455.<br />
Murine Osteoblast Primary Cultures<br />
Schainberg,APM., Özyeğin,LS., Kursuoğlu,P., Valério,P., Goes,AM. and Leite,MF. (2005) <strong>Bio</strong>compatibility evaluation of<br />
Zeolite compared to bone HA, calcium phosphate (Ca2PO4) and Eugenol Paste. Key Engineering Materials 284-<br />
286, 561-564.<br />
Murine Lung Tissue<br />
Strieter,R.M., Keane,M.P., Burdick,M.D., Sakkour,A., Murray,L.A. and Belperio,J.A. (2005) The role of CXCR2/CXCR2<br />
ligands in acute lung injury. Curr.Drug Targets Inflamm.Allergy, 4, 299-303.
Human Hepatic Stellate LI90 Cell Line<br />
Sugimoto,R., Enjoji,M., Nakamuta,M., Ohta,S., Kohjima,M., Fukushima,M., Kuniyoshi,M., Arimura,E., Morizono,S. and<br />
Kotoh,K. (2005) Effect of IL-4 and IL-13 on collagen production in cultured LI90 human hepatic stellate cells.<br />
Liver International, 25, 420-428.<br />
Ovine Fetal and Adult Chondrocytes<br />
Terada,S., Fuchs,J.R., Yoshimoto,H., Fauza,D.O. and Vacanti,J.P. (2005) In Vitro Cartilage Regeneration From<br />
Proliferated Adult Elastic Chondrocytes. Annals of Plastic Surgery, 55, 196-201.<br />
Ovine Chondrocytes<br />
Terada,S., Yoshimoto,H., Fuchs,J.R., Sato,M., Pomerantseva,I., Selig,M.K., Hannouche,D. and Vacanti,J.P. (2005)<br />
Hydrogel optimization for cultured elastic chondrocytes seeded onto a polyglycolic acid scaffold.<br />
J.<strong>Bio</strong>med.Mater.Res.75A, 907-916.<br />
Murine Osteoblast Primary Culture<br />
Valério,P., Guimarbes,M.H.R., Pereira,M.M., Leite,M.F. and Goes,A.M. (2005) Primary osteoblast cell response to solgel<br />
derived bioactive glass foams. Journal of Materials Science: Materials in Medicine, 16, 851-856.<br />
Human Fibroblast Primary Culture<br />
Vancheri,C., Gili,E., Failla,M., Mastruzzo,C., Salinaro,E.T., LoFurno,D., Pistorio,M.P., La Rosa,C., Caruso,M. and<br />
Crimi,N. (2005) Bradykinin differentiates human lung fibroblasts to a myofibroblast phenotype via the B2<br />
receptor. The Journal of Allergy and Clinical Immunology, 116, 1242-1248.<br />
Murine Lung Homogenate<br />
Vittal, R., Horowitz, J. C., Moore, B. B., Zhang, H., Martinez, F. J., Toews, G. B., Standiford, T. J., and Thannickal, V.<br />
J. (2005) Modulation of Prosurvival Signaling in Fibroblasts by a Protein Kinase Inhibitor Protects against<br />
Fibrotic Tissue Injury. American Journal of Pathology 166, 367-375.<br />
Canine Arterial Tissue<br />
Yamaguchi-Okada,M., Nishizawa,S., Koide,M. and Nonaka,Y. (2005) <strong>Bio</strong>mechanical and phenotypic changes in the<br />
vasospastic canine basilar artery after subarachnoid hemorrhage. Journal of Applied Physiology, 99, 2045-<br />
2052.<br />
Murine Pancreatic Tissue<br />
Yoo,B.M., Yeo,M., Oh,T.Y., Choi,J.H., Kim,W.W., Kim,J.H., Cho,S.W., Kim,S.J. and Hahm,K.B. (2005) Amelioration of<br />
pancreatic fibrosis in mice with defective TGF-beta signaling. Pancreas, 30, e71-e79.<br />
Murine Pancreatic Tissue<br />
Yoo,B.M., Oh,T.Y., Kim,Y.B., Yeo,M., Lee,J.S., Surh,Y.J., Ahn,B.O., Kim,W.H., Sohn,S. and Kim,J.H. (2005) Novel<br />
Antioxidant Ameliorates the Fibrosis and Inflammation of Cerulein-Induced Chronic Pancreatitis in a Mouse<br />
Model. Pancreatology, 5, 165-176.<br />
Murine Hepatic Stellate Cells<br />
Zhou,Y-j., Yin,D-m., Chen,H-s., Shi,J-h., Sha,B-x. and Wang,X. (2005) Inhibitory effects of idoxifene on hepatic fibrosis<br />
in rats. Acta Pharmacologia Sinica, 26, 581-586.
2004<br />
Murine Lung Homogenate<br />
Barbarin, V., Arras, M., Misson, P., Delos, M., McGarry, B., Phan, S. H., Lison, D., and Huaux, F. (2004)<br />
Characterization of the Effect of Interleukin-10 on Silica-Induced Lung Fibrosis in Mice. American Journal of<br />
Respiratory Cell and Molecular <strong>Bio</strong>logy 31, 78-85. 299.<br />
Murine Lung Homogenates<br />
Belperio,J.A., Dy,M., Murray,L., Burdick,M.D., Xue,Y.Y., Strieter,R.M. and Keane,M.P. (2004) The Role of the Th2 CC<br />
Chemokine Ligand CCL17 in Pulmonary Fibrosis 1. The Journal of Immunology, 173, 4692-4698.<br />
Human Lung Tissue Samples and Murine Lung Homogenates<br />
Berman,J.S., Serlin,D., Li,X., Whitley,G., Hayes,J., Rishikof,D.C., Ricupero,D.A., Liaw,L., Goetschkes,M. and<br />
O'Regan,A.W. (2004) Altered bleomycin-induced lung fibrosis in osteopontin-deficient mice. American Journal<br />
of Physiology- Lung Cellular and Molecular Physiology, 286, 1311-1318.<br />
Murine Mammary Carcinoma MCa Cell Line<br />
Casarsa,C., Mischis,M.T. and Sava,G. (2004) TGFbeta1 regulation and collagen-release-independent connective tissue<br />
re-modelling by the ruthenium complex NAMI-A in solid tumours. Journal of Inorganic <strong>Bio</strong>chemistry, 98, 1648-<br />
1654.<br />
Murine Lung Samples<br />
Cho,J. (2004) ISS inhibits expression of MMP-9 and MMP-2 in a mouse model of airway remodeling. The Journal of<br />
Allergy and Clinical Immunology, 113, 92.<br />
Human Patellar Tendon Fibroblasts<br />
Cilli,F., Khan,M., Fu,F. and Wang,J.H. (2004) Prostaglandin E2 affects proliferation and collagen synthesis by human<br />
patellar tendon fibroblasts. Clin J Sport Med, 14, 232-236.<br />
Human Pediatric Aortic Cells<br />
Fu,P., Sodian,R., Luders,C., Lemke,T., Kraemer,L., Hubler,M., Weng,Y., Hoerstrup,S.P., Meyer,R. and Hetzer,R. (2004)<br />
Effects of basic fibroblast growth factor and transforming growth factor-beta on maturation of human pediatric<br />
aortic cell culture for tissue engineering of cardiovascular structures. ASAIO J, 50, 9-14.<br />
Murine Bronchoalveolar Lavage Fluid<br />
Hattori, N., Mizuno, S., Yoshida, Y., Chin, K., Mishima, M., Sisson, T. H., Simon, R. H., Nakamura, T., and Miyake, M.<br />
(2004) The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-<br />
Dependent Mechanism. American Journal of Pathology, 164, 1091-1098.<br />
Murine Lung Samples<br />
Honda,K., Marquillies,P., Capron,M. and Dombrowicz,D. (2004) Peroxisome proliferator-activated receptor γ is<br />
expressed in airways and inhibits features of airway remodeling in a mouse asthma model. The Journal of<br />
Allergy and Clinical Immunology, 113, 882-888.<br />
Murine Liver Tissues<br />
Hsu,Y.C., Chiu,Y.T., Lee,C.Y., Lin,Y.L. and Huang,Y.T. (2004) Increases in fibrosis-related gene transcripts in livers of<br />
dimethylnitrosamine-intoxicated rats. Journal of <strong>Bio</strong>medical Science, 11, 408-417.
Murine Periodontal Ligament Cells<br />
Inoue,M., LeGeros,R.Z., Hoffman,C., Diamond,K., Rosenberg,P.A. and Craig,R.G. (2004) Effect of enamel matrix<br />
proteins on the phenotype expression of periodontal ligament cells cultured on dental materials. Journal of<br />
<strong>Bio</strong>medical Materials Research, 69, 172-179.<br />
Murine Osteoblast-like (MC3T3-E1) and Odontoblast-like (MDPC23) Cell Lines<br />
Inoue,M., LeGeros,R.Z., Inoue,M., Tsujigiwa,H., Nagatsuka,H., Yamamoto,T. and Nagai,N. (2004) In vitro response of<br />
osteoblast-like and odontoblast-like cells to unsubstituted and substituted apatites. Journal of <strong>Bio</strong>medical<br />
Materials Research, 70, 585-593.<br />
Murine Lung Homogenates<br />
Kolodsick,J.E., Toews,G.B., Jakubzick,C., Hogaboam,C., Moore,T.A., McKenzie,A., Wilke,C.A., Chrisman,C.J. and<br />
Moore,B.B. (2004) Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-<br />
Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts 1. The Journal of Immunology, 172,<br />
4068-4076.<br />
Murine Hepatic Stellate Cells and Liver Tissue and Human Hepatic Stellate (TWNT-4) Cell Line<br />
Kotoh,K., Nakamuta,M., Kohjima,M., Fukushima,M., Morizono,S., Kobayashi,N., Enjoji,M. and Nawata,H. (2004) Arg-<br />
Gly-Asp (RGD) peptide ameliorates carbon tetrachloride-induced liver fibrosis via inhibition of collagen<br />
production and acceleration of collagenase activity. Int J Mol Med, 14, 1049-1053.<br />
Human Fibroblast (NHDF) Cell Line<br />
Koya-Miyata,S., Okamoto,I., Ushio,S., Iwaki,K., Ikeda,M. and Kurimoto,M. (2004) Identification of a Collagen<br />
Production-promoting Factor from an Extract of Royal Jelly and Its Possible Mechanism. <strong>Bio</strong>science,<br />
<strong>Bio</strong>technology, and <strong>Bio</strong>chemistry, 68, 767-773.<br />
Human Dermal <strong>Bio</strong>psy<br />
Lateef, H., Stevens, M. J., and Varani, J. (2004) All-trans-Retinoic Acid Suppresses Matrix Metalloproteinase Activity<br />
and Increases Collagen Synthesis in Diabetic Human Skin in Organ Culture. American Journal of Pathology 165,<br />
167-174.<br />
Human and Murine Bone Marrow Stromal Fibroblasts<br />
Lawson,M.A., Barralet,J.E., Wang,L., Shelton,R.M. and Triffitt,J.T. (2004) Adhesion and Growth of Bone Marrow<br />
Stromal Cells on Modified Alginate Hydrogels. Tissue Engineering, 10, 1480-1491.<br />
Murine Lung Homogenates<br />
Lee,C.G., Link,H., Baluk,P., Homer,R.J., Chapoval,S., Bhandari,V., Kang,M.J., Cohn,L., Kim,Y.K. and McDonald,D.M.<br />
(2004) Vascular endothelial growth factor (VEGF) induces remodeling and enhances T H 2-mediated<br />
sensitization and inflammation in the lung. Nature Medicine, 10, 1095-1103.<br />
Leporine Chondrocytes<br />
Lee,J. and Son,Y. (2004) TGF-beta Stimulates Conversion of Fibrocartilage Phenotype of Costal Chondrocytes. Tissue<br />
Eng.Reg.Med, 1, 171-177.<br />
Human Embryonic Kidney (HEK-293, 293-EBNA and 293-T) Cell Lines and Human Fibrosarcoma (HT-1080)<br />
Cell Line<br />
Leitinger,B., Steplewski,A. and Fertala,A. (2004) The D2 period of collagen II contains a specific binding site for the<br />
human discoidin domain receptor, DDR2. J Mol <strong>Bio</strong>l, 344, 993-1003.
Human Cardiac Left Ventricle Tissue<br />
Liang,H., Müller,J., Weng,Y.G., Wallukat,G., Fu,P., Lin,HS, Bartel,S., Knosalla,C., Pregla,R. and<br />
Hetzer,R.(2004) Changes in myocardial collagen content before and after left ventricular assist device<br />
application in dilated cardiomyopathy. Chinese Medical Journal, 117, 401-407.<br />
Murine Lung Homogenate<br />
Mcmillan,S.J. and Lloyd,C.M. (2004) Prolonged allergen challenge in mice leads to persistent airway remodelling.<br />
Clinical & Experimental Allergy, 34, 497-507.<br />
Human Colonic Tissue<br />
Mimura,T., Bateman,A.C., Lee,R.L., Johnson,P.A., McDonald,P.J., Talbot,I.C., Kamm,M.A., MacDonald,T.T. and<br />
Pender,S.L.F. (2004) Up-Regulation of Collagen and Tissue Inhibitors of Matrix Metalloproteinase in Colonic<br />
Diverticular Disease. Diseases of the Colon & Rectum, 47, 371-379.<br />
Murine Dermal Tissue<br />
Nomura,Y., Taniguchi,M., Miyata,M., Ariyasu,T., Yamauchi,H., Ikeda,M. and Kurimoto,M. (2004) Interferon-gamma<br />
liniment protects hairless mice against ultraviolet irradiation-induced skin damage. <strong>Bio</strong>medical Research, 25,<br />
277-285.<br />
Murine Lung Tissue<br />
Ono, M., Sawa, Y., Mizuno, S., Fukushima, N., Ichikawa, H., Bessho, K., Nakamura, T., and Matsuda, H. (2004)<br />
Hepatocyte Growth Factor Suppresses Vascular Medial Hyperplasia and Matrix Accumulation in Advanced<br />
Pulmonary Hypertension of Rats. Circulation, 110, 2896-2902.<br />
Murine Gingival Fibroblasts<br />
Paik,J.W., Kim,C.S., Cho,K.S., Chai,J.K., Kim,C.K. and Choi,S.H. (2004) Inhibition of cyclosporin A-induced gingival<br />
overgrowth by azithromycin through phagocytosis: an in vivo and in vitro study. J Periodontol, 75, 380-387.<br />
Murine Lung Tissue<br />
Phillips,R.J., Burdick,M.D., Hong,K., Lutz,M.A., Murray,L.A., Xue,Y.Y., Belperio,J.A., Keane,M.P. and Strieter,R.M.<br />
(2004) Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. Journal of Clinical<br />
Investigation, 114, 438-446.<br />
Leporine Bronchoalveolar Lavage Fluid<br />
Schmidt,R., Ruppert,C., Markart,P., Lubke,N., Ermert,L., Weissmann,N., Breithecker,A., Ermert,M., Seeger,W. and<br />
Gunther,A. (2004) Changes in pulmonary surfactant function and composition in bleomycin-induced<br />
pneumonitis and fibrosis. Toxicology and Applied Pharmacology, 195, 218-231.<br />
Ovine, Leporine and Murine Tissue Constructs<br />
Shieh,S.J. and Terada,S. (2004) Tissue engineering auricular reconstruction: in vitro and in vivo studies. <strong>Bio</strong>materials,<br />
25, 1545-1557.<br />
Bovine Collagen<br />
Skilbeck,C.A., Walker,P.G., David,T. and Nash,G.B. (2004) Disturbed flow promotes deposition of leucocytes from<br />
flowing whole blood in a model of a damaged vessel wall. British Journal of Haematology, 126, 418-427.<br />
Human Fibrosarcoma (HT-1080) Cell Line Procollagen<br />
Steplewski,A., Ito,H., Rucker,E., Brittingham,R.J., Alabyeva,T., Gandhi,M., Ko,F.K., Birk,D.E., Jimenez,S.A. and<br />
Fertala,A. (2004) Position of single amino acid substitutions in the collagen triple helix determines their effect<br />
on structure of collagen fibrils. J Struct <strong>Bio</strong>l, 148, 326-337.
Murine Lung Homogenates<br />
Sue,R.D., Belperio,J.A., Burdick,M.D., Murray,L.A., Xue,Y.Y., Dy,M.C., Kwon,J.J., Keane,M.P. and Strieter,R.M. (2004)<br />
CXCR2 Is Critical to Hyperoxia-Induced Lung Injury 1. The Journal of Immunology, 172, 3860-3868.<br />
Human Lymphoblast-like Jurkat D1.1 and E6-1 Cell Lines and Human Primary Fibroblast Lines<br />
Suppl,A., Yurovsky,V.V. and White,B. (2004) Effect of CD154-CD40 interactions on collagen production by fibroblasts.<br />
Arthritis Res. 3A, P062.<br />
Human Dermal Fibroblasts<br />
Suzuki,M., Tanabe,F., Nakamura,S., Motoda,R. and Orita,K. (2004) NK-355, an aminovinyl photosensitizing dye,<br />
enhances collagen production through TGF-β1 upregulation. Journal of Dermatological Science, 34, 56-58.<br />
Murine Brain Tissue<br />
Tang,J., Liu,J., Zhou,C., Alexander,J.S., Nanda,A., Granger,D.N. and Zhang,J.H. (2004) MMP-9 Deficiency Enhances<br />
Collagenase-Induced Intracerebral Hemorrhage and Brain Injury in Mutant Mice. Journal of Cerebral Blood Flow<br />
& Metabolism, 24, 1133-1145.<br />
Murine Osteoblast Primary Culture<br />
Valerio,P., Pereira,M.M., Goes,A.M. and Leite,M.F. (2004) The effect of ionic products from bioactive glass dissolution<br />
on osteoblast proliferation and collagen production. <strong>Bio</strong>materials, 25, 2941-2948.<br />
Murine Thrombi<br />
Varma,M.R., Moaveni,D.M., Dewyer,N.A., Varga,A.J., Deatrick,K.B., Kunkel,S.L., Upchurch Jr,G.R., Wakefield,T.W.<br />
and Henke,P.K. (2004) Deep vein thrombosis resolution is not accelerated with increased neovascularization. J<br />
Vasc Surg, 40, 536-542.<br />
Murine Primary Hepatic Stellate Cell Line<br />
Wada,W., Kuwano,H., Hasegawa,Y. and Kojima,I. (2004) The Dependence of Transforming Growth Factor-β-Induced<br />
Collagen Production on Autocrine Factor Activin A in Hepatic Stellate Cells. Endocrinology, 145, 2753-2759.<br />
Murine Pancreatic Stellate Cells<br />
Watanabe,S., Nagashio,Y., Asaumi,H., Nomiyama,Y., Taguchi,M., Tashiro,M., Kihara,Y., Nakamura,H. and Otsuki,M.<br />
(2004) Pressure activates rat pancreatic stellate cells. American Journal of Physiology- Gastrointestinal and<br />
Liver Physiology, 287, 1175-1181.<br />
Murine Dermal <strong>Bio</strong>psy<br />
Yamamoto,T. and Nishioka,K. (2004) Animal model of sclerotic skin. VI: Evaluation of bleomycin-induced skin sclerosis<br />
in nude mice. Archives of Dermatological Research, 295, 453-456.<br />
Murine Dermal <strong>Bio</strong>psy<br />
Yamamoto,T. and Nishioka,K. (2004) Possible Role of Apoptosis in the Pathogenesis of Bleomycin-Induced Scleroderma.<br />
Journal of Investigative Dermatology, 122, 44-50.<br />
Human Left Ventricle Tissue <strong>Bio</strong>psies<br />
Zhang,J. and Narula,J. (2004) Molecular biology of myocardial recovery. Surg Clin North Am, 84, 223-242.
Human Pulmonary Fibroblasts<br />
Zhang,L., Keane,M.P., Zhu,L.X., Sharma,S., Rozengurt,E., Strieter,R.M., Dubinett,S.M. and Huang,M. (2004)<br />
Interleukin-7 and Transforming Growth Factor-{beta} Play Counter-regulatory Roles in Protein Kinase C-{delta}dependent<br />
Control of Fibroblast Collagen Synthesis in Pulmonary Fibrosis. Journal of <strong>Bio</strong>logical Chemistry,<br />
279, 28315-28319.<br />
2003<br />
Murine Lung Homogenates<br />
Blackburn,M.R., Lee,C.G., Young,H.W.J., Zhu,Z., Chunn,J.L., Kang,M.J., Banerjee,S.K. and Elias,J.A. (2003) Adenosine<br />
mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine<br />
amplification pathway. Journal of Clinical Investigation, 112, 332-344.<br />
Trout Plasma, Endolymph and Otolith Explant<br />
Borelli,G., Guibbolini,M.E., Mayer-Gostan,N., Priouzeau,F., De Pontual,H., Allemand,D., Puverel,S., Tambutte,E. and<br />
Payan,P. (2003) Daily variations of endolymph composition: relationship with the otolith calcification process in<br />
trout. Journal of Experimental <strong>Bio</strong>logy, 206, 2685-2692.<br />
Human Fibroblasts<br />
Cabral,W.A., Mertts,M.V., Makareeva,E., Colige,A., Tekin,M., Pandya,A., Leikin,S. and Marini,J.C. (2003) Type I<br />
Collagen Triplet Duplication Mutation in Lethal Osteogenesis Imperfecta Shifts Register of a Chains throughout<br />
the Helix and Disrupts Incorporation of Mutant Helices into Fibrils and Extracellular Matrix. Journal of<br />
<strong>Bio</strong>logical Chemistry, 278, 10006-10012.<br />
Murine Lung Samples<br />
Chung,MP., Monick,MM., Hamzeh,NY., Butler,NS., Powers,LS. and Hunninghake,GW. (2003) Role of repeated lung injury<br />
and genetic background in bleomycin-induced fibrosis. American Journal of Respiratory Cell and Molecular<br />
<strong>Bio</strong>logy 29, 375-380.<br />
Murine Dermal <strong>Bio</strong>psy<br />
Denton,C.P., Zheng,B., Evans,L.A., Shi-wen,X., Ong,V.H., Fisher,I., Lazaridis,K., Abraham,D.J., Black,C.M. and de<br />
Crombrugghe,B. (2003) Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor<br />
β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice.<br />
Journal of <strong>Bio</strong>logical Chemistry, 278, 25109-25119.<br />
Human Atherosclerotic Plaques<br />
Goncalves, I., Moses, J., Dias, N., Pedro, L. M., Fernandes e Fernandes, Nilsson, J., and Ares, M. P. S. (2003) Changes<br />
Related to Age and Cerebrovascular Symptoms in the Extracellular Matrix of Human Carotid Plaques. Stroke 34,<br />
616-622.<br />
Murine Lung Homogenates<br />
Huaux,F., Liu,T., McGarry,B., Ullenbruch,M., Xing,Z. and Phan,S.H. (2003) Eosinophils and T Lymphocytes Possess<br />
Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis 1. The Journal of Immunology, 171, 5470-5481.<br />
Murine Fibroblasts<br />
Huaux,F., Liu,T., McGarry,B., Ullenbruch,M. and Phan,S.H. (2003) Dual Roles of IL-4 in Lung Injury and Fibrosis 1. The<br />
Journal of Immunology, 170, 2083-2092.
Murine Lung Hydrolysates<br />
Hutson,P.R., Crawford,M.E. and Sorkness,R.L. (2003) Liquid chromatographic determination of hydroxyproline in tissue<br />
samples. Journal of Chromatography B, Analytical Technologies in the <strong>Bio</strong>medical and Life Sciences, 791, 427-<br />
430.<br />
Leporine Chondrocytes<br />
Ibusuki,S., Fujii,Y., Iwamoto,Y. and Matsuda,T. (2003) Tissue-Engineered Cartilage Using an Injectable and in Situ<br />
Gelable Thermoresponsive Gelatin: Fabrication and in Vitro Performance. Tissue Engineering, 9, 371-384.<br />
Murine Osteoblast-like MC3T3-E1 Cell Line<br />
Luppen,C.A., Smith,E., Spevak,L., Boskey,A.L. and Frenkel,B. (2003) Bone morphogenetic protein-2 restores<br />
mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures. J Bone Miner Res, 18,1186-1197.<br />
Murine Osteoblast-like MC3T3-E1 Subclone Cell Line<br />
Luppen,C.A., Leclerc,N., Noh,T., Barski,A., Khokhar,A., Boskey,A.L., Smith,E. and Frenkel,B. (2003) Brief Bone<br />
Morphogenetic Protein 2 Treatment of Glucocorticoid-inhibited MC3T3-E1 Osteoblasts Rescues Commitmentassociated<br />
Cell Cycle and Mineralization without Alteration of Runx2. Journal of <strong>Bio</strong>logical Chemistry, 278,<br />
44995-45003.<br />
Murine Pancreatic Stellate Cells<br />
Ohnishi, N., Miyata, T., Ohnishi, H., Yasuda, H., Tamada, K., Ueda, N., Mashima, H., and Sugano, K. (2003) Activin A is<br />
an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic<br />
fibrosis. Gut 52, 1487-1493.<br />
Porcine, Ovine and Tissue-Engineered Cardiac Valve Leaflets<br />
Schenke-Layland,K., Opitz,F., Gross,M., Döring,C., Halbhuber,K.J., Schirrmeister,F., Wahlers,T. and Stock,U.A. (2003)<br />
Complete dynamic repopulation of decellularized heart valves by application of defined physical signals - an in<br />
vitro study. Cardiovascular Research, 60, 497-509.<br />
Murine Lung Homogenate<br />
Suzuki, H., Aoshiba, K., Yokohori, N., and Nagai, A. (2003) Epidermal Growth Factor Receptor Tyrosine Kinase<br />
Inhibition Augments a Murine Model of Pulmonary Fibrosis 1. Cancer Research 63, 5054-5059.<br />
Murine Thrombi<br />
Thanaporn,P., Myers,D.D., Wrobleski,S.K., Hawley,A.E., Farris,D.M., Wakefield,T.W. and Henke,P.K. (2003) P-selectin<br />
inhibition decreases post-thrombotic vein wall fibrosis in a rat model. Surgery, 134, 365-371.<br />
Murine Osteoblast Primary Culture<br />
Valério,P., Goes,A.M., Pereira,M.M. and Leite,M.F. (2003) Cytological and biochemical evaluation of osteoblast in<br />
contact with ionic products of bioactive ceramics. Key Engineering Materials, 240, 703-706.<br />
Murine Plasma<br />
Vergnes,L., Phan,J., Strauss,M., Tafuri,S. and Reue,K. (2003) Cholesterol and Cholate Components of an Atherogenic<br />
Diet Induce Distinct Stages of Hepatic Inflammatory Gene Expression. Journal of <strong>Bio</strong>logical Chemistry, 278,<br />
42774-42784.<br />
Murine Dermal <strong>Bio</strong>psy<br />
Yamamoto,T. and Nishioka,K. (2003) Role of Monocyte Chemoattractant Protein-1 and its Receptor, CCR-2, in the<br />
Pathogenesis of Bleomycin-Induced Scleroderma. Journal of Investigative Dermatology, 121, 510-516.
Human Lung Fibroblast (8F1024, 8F1608 and 9F0892) Cell Lines<br />
Yurovsky,VV. (2003) Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Enhances Collagen Production by Human<br />
Lung Fibroblasts. American Journal of Respiratory Cell and Molecular <strong>Bio</strong>logy, 28, 225-231.<br />
2002<br />
Murine Lung Homogenates<br />
Blease, K., Schuh, J. M., Jakubzick, C., Lukacs, N. W., Kunkel, S. L., Joshi, B. H., Puri, R. K., Kaplan, M. H., and<br />
Hogaboam, C. M. (2002) Stat6-Deficient Mice Develop Airway Hyperresponsiveness and Peribronchial Fibrosis<br />
during Chronic Fungal Asthma. American Journal of Pathology 160(2), 481-490.<br />
Human Pulmonary Fibrosis Fibroblasts, Normal Fibroblasts, U4A, U3A, and U4A/JAK1 Cell Lines and Murine<br />
Lung Samples<br />
Huang,M., Sharma,S., Zhu,L.X., Keane,M.P., Luo,J., Zhang,L., Burdick,M.D., Lin,Y.Q., Dohadwala,M. and Gardner,B.<br />
(2002) IL-7 inhibits fibroblast TGF-β production and signaling in pulmonary fibrosis. Journal of Clinical<br />
Investigation, 109, 931-937.<br />
Murine Lung Homogenates<br />
Jain,V.V., Kitagaki,K., Businga,T., Hussain,I., George,C., O'Shaughnessy,P. and Kline,J.N. (2002) CpGoligodeoxynucleotides<br />
inhibit airway remodeling in a murine model of chronic asthma. The Journal of Allergy<br />
and Clinical Immunology, 110, 867-872.<br />
Murine Liver Samples<br />
Kitamura,K., Nakamoto,Y., Akiyama,M., Fujii,C., Kondo,T., Kobayashi,K., Kaneko,S. and Mukaida,N. (2002) Pathogenic<br />
Roles of Tumor Necrosis Factor Receptor p55-Mediated Signals in Dimethylnitrosamine-Induced Murine Liver<br />
Fibrosis. Lab Invest, 82, 571-584.<br />
Cultured Neonatal Heart Smooth-Muscle Cells<br />
Langford,S.D., Trent,M.B. and Boor,P.J. (2002) Semicarbazide-sensitive amine oxidase and extracellular matrix<br />
deposition by smooth-muscle cells. Cardiovascular Toxicology, 2, 141-150.<br />
Murine Lung Homogenates<br />
Lanone,S., Zheng,T., Zhu,Z., Liu,W., Lee,C.G., Ma,B., Chen,Q., Homer,R.J., Wang,J. and Rabach,L.A. (2002)<br />
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and-12 in IL-13-induced<br />
inflammation and remodeling. Journal of Clinical Investigation, 110, 463-474.<br />
Murine Cardiac Samples<br />
Li,Y.Y., Kadokami,T., Wang,P., McTiernan,C.F. and Feldman,A.M. (2002) MMP inhibition modulates TNF-a transgenic<br />
mouse phenotype early in the development of heart failure. American Journal of Physiology- Heart and<br />
Circulatory Physiology, 282, 983-989.<br />
Murine Glomerular Mesangial Cells<br />
Routh,R., McCarthy,K. and Welbourne,T. (2002) Troglitazone inhibits glutamine metabolism in rat mesangial cells.<br />
American Journal of Physiology- Endocrinology and Metabolism, 282, 231-238.<br />
Murine Lung Tissue<br />
Schuh,JM., Power,CA., Proudfoot,AE., Kunkel,SL, Lukacs,NW and Hogaboam,CM. (2002) Airway hyperresponsiveness,<br />
but not airway remodeling, is attenuated during chronic pulmonary allergic responses to aspergillus in CCR4-/-<br />
mice. FASEB J. 16, 1313-1315.
Murine Lung Tissue<br />
Suhara, H., Sawa, Y., Fukushima, N., Kagisaki, K., Yokoyama, C., Tanabe, T., Ohtake, S., and Matsuda, H. (2002) Gene<br />
transfer of human prostacyclin synthase into the liver is effective for the treatment of pulmonary hypertension<br />
in rats. The Journal of Thoracic and Cardiovascular Surgery 123, 855-861.<br />
Murine Dermal Tissue<br />
Takeda,U., Utani,A., Wu,J., Adachi,E., Koseki,H., Taniguchi,M., Matsumoto,T., Ohashi,T., Sato,M. and Shinkai,H.<br />
(2002) Targeted Disruption of Dermatopontin Causes Abnormal Collagen Fibrillogenesis. Journal of<br />
Investigative Dermatology, 119, 678-683.<br />
Murine Dermal <strong>Bio</strong>psy<br />
Yamamoto,T. and Nishioka,K. (2002) Analysis of the effect of halofuginone on bleomycin-induced scleroderma.<br />
Rheumatology, 41, 594-596.<br />
2001<br />
Bovine Chondrocytes<br />
Amiel,G.E., Yoo,J.J., Kim,B.S. and Atala,A. (2001) Tissue engineered stents created from chondrocytes. J Urol, 165,<br />
2091-2095.<br />
Human Granulosa Cells<br />
Aston,K.E., Stamouli,A., Thomas,E.J., Vyas,S., Iredale,J.P., Arthur,M.J.P. and Richardson,M.C. (2001) Endocrinology<br />
and paracrinology Effect of gonadotrophin on cell and matrix retention and expression of metalloproteinases<br />
and their inhibitor in cultured human granulosa cells modelling corpus luteum function. Molecular Human<br />
Reproduction, 2, 26-30.<br />
Murine Lung Homogenates<br />
Blease,K., Jakubzick,C., Schuh,J.M., Joshi,B.H., Puri,R.K. and Hogaboam,C.M. (2001) IL-13 Fusion Cytotoxin<br />
Ameliorates Chronic Fungal-Induced Allergic Airway Disease in Mice 1. The Journal of Immunology, 167, 6583-<br />
6592.<br />
Trout and Turbot Endolymph and Otoliths<br />
Borelli,G., Mayer-Gostan,N., De Pontual,H., Boeuf,G. and Payan,P. (2001) <strong>Bio</strong>chemical Relationships Between<br />
Endolymph and Otolith Matrix in the Trout (Oncorhynchus mykiss) and Turbot (Psetta maxima). Calcified<br />
Tissue International, 69, 356-364.<br />
Human Dermal Fibroblasts<br />
Bouma,P., Cabral,W.A., Cole,W.G. and Marini,J.C. (2001) COL5A1 Exon 14 Splice Acceptor Mutation Causes a<br />
Functional Null Allele, Haploinsufficiency of a1 (V) and Abnormal Heterotypic Interstitial Fibrils in Ehlers-Danlos<br />
Syndrome II. Journal of <strong>Bio</strong>logical Chemistry, 276, 13356-13364.<br />
Leporine Lens Epithelial Cells<br />
Ishida,I., Saika,S. and Ohnishi,Y. (2001) Effect of minoxidil on rabbit lens epithelial cell behavior in vitro and in situ.<br />
Graefe's Archive for Clinical and Experimental Ophthalmology, 239, 770-777.<br />
Leporine Lens Epithelial Cells<br />
Ishida,I.K.U. (2001) Experimental study on the efficacy of minoxidil in preventing postoperative capsular opacification.<br />
Journal of the Wakayama Medical Society, 52, 207-215.
Murine Lung Homogenates<br />
Lee,C.G., Homer,R.J., Zhu,Z., Lanone,S., Wang,X., Koteliansky,V., Shipley,J.M., Gotwals,P., Noble,P. and Chen,Q.<br />
(2001) Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth<br />
Factor β1. Journal of Experimental Medicine, 194, 809-822.<br />
Human Left Ventricle Samples<br />
Li, Y. Y., Feng, Y., McTiernan, C. F., Pei, W., Moravec, C. S., Wang, P., Rosenblum, W., Kormos, R. L., and Feldman,<br />
A. M. (2001) Downregulation of Matrix Metalloproteinases and Reduction in Collagen Damage in the Failing<br />
Human Heart After Support With Left Ventricular Assist Devices. Circulation 104, 1147-1152.<br />
Murine Renal Tissue<br />
Mizuno,S., Matsumoto,K. and Nakamura,T. (2001) Hepatocyte growth factor suppresses interstitial fibrosis in a mouse<br />
model of obstructive nephropathy. Kidney International, 59, 1304-1314.<br />
Rat Fetal Lung Fibroblast (RFL-6) Cell Line<br />
Samimi,A. and Last,J.A. (2001) Inhibition of Lysyl Hydroxylase by Malathion and Malaoxon. Toxicology and Applied<br />
Pharmacology, 172, 203-209.<br />
2000<br />
Rat Aortic Smooth Muscle Cells and Pig Auricular Chondrocytes<br />
Brown, AN., Kim, BS., Alsberg,E. And Mooney,DJ.(2000) Combining Chondrocytes and Smooth Muscle Cells to Engineer<br />
Hybrid Soft Tissue Constructs. Tissue Engineering, 6, 297-305.<br />
Human Primary Fibroblast Cultures<br />
Kurasawa,K., Hirose,K., Sano,H., Endo,H., Shinkai,H., Nawata,Y., Takabayashi,K. and Iwamoto,I. (2000) Increased<br />
interleukin-17 production in patients with systemic sclerosis. Arthritis & Rheumatism, 43, 2455-2463.<br />
Murine Cardiac Left Ventricles<br />
Li,Y.Y., Feng,Y.Q., Kadokami,T., McTiernan,C.F., Draviam,R., Watkins,S.C. and Feldman,A.M. (2000) Myocardial<br />
extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be<br />
modulated by anti-tumor necrosis factor alpha therapy. Proceedings of the National Academy of Sciences, 97,<br />
12746.<br />
Murine Renal Tissue<br />
Mizuno,S. (2000) Reciprocal balance of hepatocyte growth factor and transforming growth factor-β 1 in renal fibrosis in<br />
mice. Kidney International, 57, 937.<br />
Murine Lung Homogenate<br />
Tokuda,A., Itakura,M., Onai,N., Kimura,H., Kuriyama,T. and Matsushima,K. (2000) Pivotal Role of CCR1-Positive<br />
Leukocytes in Bleomycin-Induced Lung Fibrosis in Mice 1. The Journal of Immunology, 164, 2745-2751.<br />
1999<br />
Bovine Articular Chondrocyte Cultures<br />
Ioannidis,N., Kurz,B., Hansen,U. and Schünke,M. (1999) Influence of fulvic acid on the collagen secretion of bovine<br />
chondrocytes in vitro. Cell and Tissue Research, 297, 141-147.
Murine Dermis Samples<br />
Jimenez,P.A. and Rampy,M.A. (1999) Keratinocyte Growth Factor-2 Accelerates Wound Healing in Incisional Wounds.<br />
Journal of Surgical Research, 81, 238-242.<br />
Murine Tail Tendon<br />
Kuznetsova,N. and Leikin,S. (1999) Does the Triple Helical Domain of Type I Collagen Encode Molecular Recognition and<br />
Fiber Assembly while Telopeptides Serve as Catalytic Domains? Effect of Proteolytic Cleavage On Fibrillogenesis<br />
And On Collagen-Collagen Interaction In Fibers. Journal of <strong>Bio</strong>logical Chemistry, 274, 36083-36088.<br />
Murine Liver Tissue<br />
Natsume, M. (1999) Attenuated liver fibrosis and depressed serum albumin levels in carbon tetrachloride-treated IL-6deficient<br />
mice. Journal of Leukocyte <strong>Bio</strong>logy 66, 601-608.<br />
Murine Bone Marrow Stromal Cells<br />
Notoya,K., Nagai,H., Oda,T., Gotoh,M., Hoshino,T., Muranishi,H., Taketomi,S., Sohda,T. and Makino,H. (1999)<br />
Enhancement of Osteogenesis In Vitro and In Vivo by a Novel Osteoblast Differentiation Promoting Compound,<br />
TAK-778. Journal of Pharmacology and Experimental Therapeutics, 290, 1054-1064.<br />
Murine Liver Tissue<br />
Shimizu,I., Mizobuchi,Y., Yasuda,M., Shiba,M., Ma,Y.R., Horie,T., Liu,F. and Ito,S. (1999) Inhibitory effect of oestradiol<br />
on activation of rat hepatic stellate cells in vivo and in vitro. Gut, 44, 127-136.<br />
Murine Liver Tissue and Primary cultures of Stellate cells and Hepatocytes<br />
Shimizu,I., Ma,Y.R., Mizobuchi,Y., Liu,F., Miura,T., Nakai,Y., Yasuda,M., Shiba,M., Horie,T. and Amagaya,S. (1999)<br />
Effects of sho-saiko-to, a japanese herbal medicine, on hepatic fibrosis in rats. Hepatology, 29, 149-160.<br />
Murine Liver Homogenate<br />
Yasuda,M., Shimizu,I., Shiba,M. and Ito,S. (1999) Suppressive effects of estradiol on dimethylnitrosamine-induced<br />
fibrosis of the liver in rats. Hepatology, 29, 719-727.<br />
1998<br />
Human Osteoblasts<br />
Andrade,A.L., Valqrio,P., Goes,A.M., Leite,M.F. and Domingues,R.Z. (1998) Behavior of Osteoblasts Cultured on<br />
Collagen Coated <strong>Bio</strong>active Glass. <strong>Bio</strong>materials, 19, 1019 – 1025.<br />
Murine Tail Tendon<br />
Knight,D.P., Nash,L., Hu,X.W., Haffegee,J. and Ho,M.W. (1998) In vitro formation by reverse dialysis of collagen gels<br />
containing highly oriented arrays of fibrils. Journal of <strong>Bio</strong>medical Materials Research, 41, 185-191.<br />
Human Bone Marrow Fibroblastic Cells<br />
Oreffo,R.O., Driessens,F.C., Planell,J.A. and Triffitt,J.T. (1998) Effects of novel calcium phosphate cements on human<br />
bone marrow fibroblastic cells. Tissue Eng, 4, 293-303.<br />
Murine Aortic Explants<br />
Tang,J., O'Callaghan,D., Rouy,S. and Godlewski,G. (1998) Quantitative changes in collagen levels following 830-nm<br />
diode laser welding. Lasers in Surgery and Medicine, 22, 207-211.
1997<br />
Human Amniotic Membrane Samples<br />
Hampson,V., Liu,D., Billett,E. and Kirk,S. (1997) Amniotic membrane collagen content and type distribution in women<br />
with preterm premature rupture of the membranes in pregnancy. BJOG: An International Journal of Obstetrics<br />
& Gynaecology, 104, 1087-1091.<br />
Murine Cardiac Ventricles<br />
Lubec,B., Hjelm,M., Hoeger,H., Gialamas,J. and Lubec,G. (1997) 4-Thiaproline reduces heart lipid peroxidation and<br />
collagen accumulation in the diabetic db/db mouse. Amino Acids, 12, 343-351.<br />
Murine Articular Cartilage<br />
Nakamura,M., Watanabe,J., Ogawa,R. and Kanamura,S. (1997) Immunohistochemical localization of type II and type I<br />
collagens in articular cartilage of the femoral head of dexamethasone-treated rats. The Histochemical<br />
Journal, 29, 645-654.<br />
Addendum (Citations with Undetermined Experimental Model)<br />
Asaumi,H., Watanabe,S., Taguchi,M., Nagashio,Y., Nomiyama,Y., Tashiro,M., Kihara,Y. and Otsuki,M. (2004) Inhibition<br />
of pancreatic stellate cell activation by green tea catechin through anti-oxidative effect. Pancreas, 29, 351.<br />
Heemskerk,J.W., Siljander,P., Vuist,W.M., Breikers,G., Reutelingsperger,C.P., Barnes,M.J., Knight,C.G., Lassila,R. and<br />
Farndale,R.W. (1999) Function of glycoprotein VI and integrin alpha2beta1 in the procoagulant response of<br />
single, collagen-adherent platelets. Thromb Haemost, 81, 782-792.<br />
Hsia-Wei Liu,P.D., Chen,C.H.W.A., Tsai,C.L.I.N., Lin,I.H. and Hsiue,G.H.O. (2007) Heterobifunctional poly(ethylene<br />
glycol)-tethered bone morphogenetic protein-2-stimulated bone marrow mesenchymal stromal cell<br />
differentiation and osteogenesis. Tissue Eng., 13, 1113-1124.<br />
Gomperts,B.N. and Strieter,R.M. (2007) Fibrocytes in Lung Disease. Journal of Leukocyte <strong>Bio</strong>logy, 82, 449.<br />
Ito,H., Steplewski,A., Alabyeva,T. and Fertala,A. (2006) Testing the utility of rationally engineered recombinant<br />
collagen-like proteins for applications in tissue engineering. J.<strong>Bio</strong>med.Mater.Res, 76, 551-560.<br />
Li,Y.Y. and Feldman,A.M. (2001) Matrix metalloproteinases in the progression of heart failure: potential therapeutic<br />
implications. Drugs, 61, 1239-1252.<br />
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