Infantile Hemangioma - CHU Sainte-Justine - SAAC

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Inpatient or Outpatient?• Inpatient hospitalization suggested for thefollowing• Infants < 8 weeks of gestationally corrected age• any age infant with inadequate social support,• any age infant with comorbid conditions affecting thecardiovascular system, the respiratory system (e.g. airwayhemangiomas, etc.• Outpatient initiation with monitoring can beconsidered for the following:• Infants/toddlers over 8 weeks of age with adequatesocial support and without significant comorbidities
Monitoring – All Patients• The peak effect of oral propranolol on HR and BP is 1 to 3hours after administration.• Patients should be monitored with HR and BP measurementat baseline and at 1 and 2 hours after receiving the initial dose• Repeat with significant dose increase (>0.5 mg/kg/day),including at least 1 set of measurements after the target dosehas been achieved.• If HR and BP are abnormal child should be monitored untilthe vitals normalize.• Dose response is usually most dramatic after the first dose;• no need to repeat for same dose unless very young or hascomorbid conditions affecting CV or resp. systems• HR easier to accurately obtain than BP.
Page 1 and 2: Infantile Hemangiomas:Approach and
Page 3 and 4: Overview• Which hemangiomas need
Page 5 and 6: How do we decidewhich hemangiomasto
Page 7 and 8: Risk of Segmentals• Segmental hem
Page 9 and 10: Residual skin changes inuntreated h
Page 11 and 12: Very Early Growth:Birth 1 year 2yea
Page 13 and 14: Very Early Growth:Study usingparent
Page 15 and 16: Timing of Initiation of Treatment~1
Page 17 and 18: Reevaluationat age 3 to 4 years•
Page 19 and 20: Propranolol as RxLéauté-Labrèze
Page 21 and 22: Results of Systematic Review• Res
Page 23: Propranolol ConsensusGuidelinesDrol
Page 27 and 28: Caveat• This information is based
Page 29 and 30: What about TopicalBeta-Blockers?
Page 31 and 32: Topical Beta-Blockers:Experience in

Infantile Hemangioma - CHU Sainte-Justine - SAAC

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