Infantile Hemangioma - CHU Sainte-Justine - SAAC

More documents

Recommendations

Info

Beta-blockers for <strong>Infantile</strong><strong>Hemangioma</strong>s: 4 years later• More than 240 articles published• Systematic Review 41 case series with≥ 10 patients: Total of 1264 patients• 28% received prior Rx, most commonlyoral prednisolone• Propranolol initiated mean age of 6.6 mos,mean dose of 2.1 mg/kg/day• Mean duration Rx 6.4 months
Results of Systematic Review• Response rate was 98% (range 82 – 100%)• Response rates ~ comparable irrespectiveof anatomic sites e.g. periorbital, airway, etc.• Rebound growth in 17%• AE rate ~ 3 to 5%, with sleep changes andacrocyanosis being most common• Serious AEs rareMarqueling et al. Poster Soc Ped Dermatol July 2012
Page 1 and 2: Infantile Hemangiomas:Approach and
Page 3 and 4: Overview• Which hemangiomas need
Page 5 and 6: How do we decidewhich hemangiomasto
Page 7 and 8: Risk of Segmentals• Segmental hem
Page 9 and 10: Residual skin changes inuntreated h
Page 11 and 12: Very Early Growth:Birth 1 year 2yea
Page 13 and 14: Very Early Growth:Study usingparent
Page 15 and 16: Timing of Initiation of Treatment~1
Page 17 and 18: Reevaluationat age 3 to 4 years•
Page 19: Propranolol as RxLéauté-Labrèze
Page 23 and 24: Propranolol ConsensusGuidelinesDrol
Page 25 and 26: Monitoring - All Patients• The pe
Page 27 and 28: Caveat• This information is based
Page 29 and 30: What about TopicalBeta-Blockers?
Page 31 and 32: Topical Beta-Blockers:Experience in

Infantile Hemangioma - CHU Sainte-Justine - SAAC

Create successful ePaper yourself

Delete template?

Save as template?