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User Guide to Thresholds and Classification - Environmental ...

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357<strong>User</strong> <strong>Guide</strong> for <strong>Thresholds</strong> <strong>and</strong> <strong>Classification</strong>sLangenberg JH, Peijnenburg WJGM, Rorije E 1996. On the usefulness <strong>and</strong> reliability of existing QSBRs forrisk assessment <strong>and</strong> priority setting. SAR <strong>and</strong> QSAR in <strong>Environmental</strong> Research 5: 1–16.Lipnick, RL 1986. Charles Ernest Over<strong>to</strong>n: Narcosis studies <strong>and</strong> a contribution <strong>to</strong> general pharmacology.Trends in Pharmacological Science 7: 161–164.Lipnick RL 1989a. Hans Horst Meyer <strong>and</strong> the lipoid theory of narcosis. Trends in Pharmacological Sciences10(7): 265–269; Erratum: 1990. 11(1): 44.Lipnick, RL 1989b. Narcosis, electrophile, <strong>and</strong> proelectrophile <strong>to</strong>xicity mechanisms. Application of SAR <strong>and</strong>QSAR. <strong>Environmental</strong> Toxicology <strong>and</strong> Chemistry 8: 1–12.Lipnick RL 1990. Narcosis: fundamental <strong>and</strong> baseline <strong>to</strong>xicity mechanism for non-electrolyte organicchemicals. In: Karcher W, Devillers, J (eds) Practical Applications of Quantitative Structure-ActivityRelationships (QSAR) in <strong>Environmental</strong> Chemistry <strong>and</strong> Toxicology. Kluwer Academic Publishers, Dordrecht,The Netherl<strong>and</strong>s, pp 129–144.Lipnick RL (ed.) 1991a. Charles Ernest Over<strong>to</strong>n: Studies of Narcosis <strong>and</strong> a Contribution <strong>to</strong> GeneralPharmacology. Chapman <strong>and</strong> Hall, London, <strong>and</strong> Wood Library-Museum of Anaesthesiology.Lipnick RL 1991b. Outliers: their origin <strong>and</strong> use in the classification of molecular mechanisms of <strong>to</strong>xicity.Science of the Total Environment 109/110: 131–153.Lipnick RL 1995. Structure-Activity Relationships. In: R<strong>and</strong>, GR (ed.) Fundamentals of Aquatic Toxicology,2nd edition. Taylor & Francis, London, pp 609–655.Loonen, H, Lindgren, F, Hansen, B, Karcher, W, Niemela, J, Hiromatsu, K, Takatsuki, M, Peijnenburg, W,Rorije, E, Struijs, J 1999. Prediction of biodegradability from chemical structure: modeling of readybiodegradation test data. <strong>Environmental</strong> Toxicology <strong>and</strong> Chemistry 18: 1763–1768.Meylan, WM, Howard, PH 1995. A<strong>to</strong>m/fragment contribution methods for estimating octanol-water partitioncoefficients. Journal of Pharmaceutical Sciences, 84: 83.OECD 1998. Detailed Review Paper on Aquatic Toxicity Testing for Industrial Chemicals <strong>and</strong> Pesticides PartI, Guidance Document No. 11. http://www.olis.oecd.org/olis/1998doc.nsf/LinkTo/env-mc-chem(98)19-part1<strong>and</strong> Part II Annexes http://www.olis.oecd.org/olis/1998doc.nsf/LinkTo/env-mc-chem(98)19-part2OECD 1999. <strong>Guide</strong>lines for Testing of Chemicals. Organisation for Economic Co-operation <strong>and</strong>Development, Paris.http://www.oecd.org/document/40/0,3343,en_2649_34377_37051368_1_1_1_1,00.html.OECD 2000. Aquatic Toxicity Testing of Difficult Substances <strong>and</strong> Mixtures, Guidance Document No. 23.Organisation for Economic Co-operation <strong>and</strong> Development, Parishttp://www.olis.oecd.org/olis/2000doc.nsf/LinkTo/env-jm-mono(2000)6 Retrieved 17 Oc<strong>to</strong>ber 2007.January 2012 EPA0109

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