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186User Guide for Thresholds and ClassificationsReferencesUnited Nations 2007. The Globally Harmonized System of Classification and Labelling of Chemicals (GHS),2nd revised edition. United Nations, Geneva.January 2012 EPA0109
187User Guide for Thresholds and ClassificationsAppendix 12A: Acceptable test methods for eye corrosion orirritancy12A.1 IntroductionMost of the guidelines mentioned in this appendix are found in compilations from the organisation issuingthem. The guidelines listed below are not exclusive. If data have been generated using other validinternational guidelines, then the results from those tests may also be applicable.The main references to international guidelines referred to in this appendix are as follows.European Commission (EC) guidelines:European Commission 1996. Classification, Packaging and Labelling of Dangerous Substances in theEuropean Union. Part 2 – Testing Methods. http://ecb.jrc.it/testing-methods Retrieved 14 August 2007.Organisation for Economic Co-operation and Development (OECD) guidelines:OECD 1993. OECD Guidelines for the Testing of Chemicals. Organisation for Economic Co-operationand Development, Paris, with regular updates.http://www.oecd.org/document/40/0,3343,en_2649_34377_37051368_1_1_1_1,00.html Retrieved 14August 2007.United States Environmental Protection Agency (USEPA) Office of Prevention, Pesticides and ToxicSubstances (OPPTS) guidelines:USEPA 2007. Harmonized Test Guidelines. United States Environmental Protection Agency.http://www.epa.gov/opptsfrs/home/guidelin.htm Retrieved 14 August 2007.12A.2 Eye corrosion or irritancy test guidelinesThe guidelines in Table 12A.1 are primarily relevant to substances that are, or solely contain, chemicalsubstances. However, the Hazardous Substances and New Organisms Act 1996 also covers biopesticidesthat include micro-organisms. More specialised test methods may be required to adequately characterise thepotential effects of biopesticides in mammals.For testing microbial biopesticides, see the USEPA website for specific tests.USEPA 2007. OPPTS Harmonized Test Guidelines: Series 885 Microbial Pesticide Test Guidelines –Final Guidelines. Office of Prevention, Pesticides and Toxic Substances, United States EnvironmentalProtection Agency.http://www.epa.gov/opptsfrs/publications/OPPTS_Harmonized/885_Microbial_Pesticide_Test_Guidelines/Series Retrieved 14 August 2007.See also Table 12A.1.January 2012 EPA0109
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