User Guide to Thresholds and Classification - Environmental ...

129User Guide for Thresholds and Classifications(SIDs)Searchable physics information notices (SPIN)Syracuse Research Corporation (SRC) environmentalfate database (BIOLOG, BIODEG, CHEMFATE,DATALOG)SRC PhysProphttp://www.scitation.aip.org/spinwebhttp://www.syrres.com/esc/efdb.htmhttp://www.syrres.com/esc/default1.htmNote: These URLs may not be the only routes to the information.9.6. DefinitionsThe following terms and definitions are particularly relevant to chapters 9–17 about toxicity.Termacute toxicityDefinitionAdverse effects occurring following the oral or dermal administration of a singledose of a substance, or multiple doses given within 24 hours, or an inhalationexposure of four hours.See United Nations (2007).aspirationATEbwcarcinogenThe entry of a liquid or solid chemical product directly through the oral or nasalcavity, or indirectly from vomiting, into the trachea and lower respiratory system.Aspiration toxicity includes severe acute effects such as chemical pneumonia,varying degrees of pulmonary injury or death following aspiration.acute toxicity estimatesbodyweightA chemical substance or mixture of chemical substances that induce cancer orincrease its incidence. Substances that have induced benign and malignanttumours in well-performed experimental studies on animals are considered tobe presumed or suspected human carcinogens unless there is strong evidencethat the mechanism of tumour formation is not relevant for humans.See United Nations (2007).conjunctival oedemaconjunctival rednesscorneal opacitydataA chemically induced swelling around the eye.See IUPAC (2007).A chemically induced redness around the eye.When the cornea becomes cloudy because of scar tissue, an injury, orinfection.Values that are directly measured, calculated, or estimated for any of themeasures given.See the Hazardous Substances (Minimum Degrees of Hazard) Regulations2001.January 2012 EPA0109