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128User Guide for Thresholds and ClassificationsEuropean Agency for Safety and Health at Workoccupational exposure limitsUnited States (US) National Institute for OccupationalSafety and Health (NIOSH) /Immediately Dangerous toLife and Health (IDLH)US NIOSH occupational health guidelinesUS NIOSH Occupational Safety & HealthAdministration (OSHA) Permissible Exposure Limits(PELs)http://europe.osha.eu.int/good_practice/risks/ds/oelhttp://www.cdc.gov/niosh/idlh/intridl4.htmlhttp://www.cdc.gov/niosh/81-123.htmlhttp://www.cdc.gov/niosh/pel88/npelname.htmlNote: These URLs may not be the only routes to the information.Table 9.20: Information sources for toxicity – material safety data sheets (MSDS)Information sourceMSDS hyper-glossaryCheminfo MSDSSIRI (Safety Information Resources Inc) MSDSURLhttp://www.ilpi.com/msds/ref/index.htmlhttp://intox.org/databank/documents/chemical/lactacid/cie794.htmhttp://hazard.com/msds/index.phpNote: These URLs may not be the only routes to the information.Table 9.21: Information sources – physico-chemical propertiesInformation sourceBeilstein handbookBiodegradation and bioaccumulation database onexisting chemicals, Japan (METI)ChemFinderChemical Evaluation Search and Retrieval System(CESARS)Hazardous Substances Data Bank (HSDB)ISHOWInternational Uniform Chemical Information Database(IUCLID) (part of European Chemical SubstancesInformation System (ESIS))International Union of Pure and Applied Chemistry(IUPAC) solubility data seriesMerck IndexOrganisation for Economic Co-operation andDevelopment (OECD) screening information data setsURLhttp://www.beilstein-online.de/frameset.htmhttp://www.safe.nite.go.jp/english/db.htmlhttp://chemfinder.cambridgesoft.comhttp://www.ccohs.ca/products/databases/cesars.htmlhttp://toxnet.nlm.nih.govhttp://www.nisc.com/cishttp://echa.europa.eu/http://www.iupac.org/publications/sdshttp://library.dialog.com/bluesheets/html/bl0304.htmlhttp://cs3-hq.oecd.org/scripts/hpvJanuary 2012 EPA0109
129User Guide for Thresholds and Classifications(SIDs)Searchable physics information notices (SPIN)Syracuse Research Corporation (SRC) environmentalfate database (BIOLOG, BIODEG, CHEMFATE,DATALOG)SRC PhysProphttp://www.scitation.aip.org/spinwebhttp://www.syrres.com/esc/efdb.htmhttp://www.syrres.com/esc/default1.htmNote: These URLs may not be the only routes to the information.9.6. DefinitionsThe following terms and definitions are particularly relevant to chapters 9–17 about toxicity.Termacute toxicityDefinitionAdverse effects occurring following the oral or dermal administration of a singledose of a substance, or multiple doses given within 24 hours, or an inhalationexposure of four hours.See United Nations (2007).aspirationATEbwcarcinogenThe entry of a liquid or solid chemical product directly through the oral or nasalcavity, or indirectly from vomiting, into the trachea and lower respiratory system.Aspiration toxicity includes severe acute effects such as chemical pneumonia,varying degrees of pulmonary injury or death following aspiration.acute toxicity estimatesbodyweightA chemical substance or mixture of chemical substances that induce cancer orincrease its incidence. Substances that have induced benign and malignanttumours in well-performed experimental studies on animals are considered tobe presumed or suspected human carcinogens unless there is strong evidencethat the mechanism of tumour formation is not relevant for humans.See United Nations (2007).conjunctival oedemaconjunctival rednesscorneal opacitydataA chemically induced swelling around the eye.See IUPAC (2007).A chemically induced redness around the eye.When the cornea becomes cloudy because of scar tissue, an injury, orinfection.Values that are directly measured, calculated, or estimated for any of themeasures given.See the Hazardous Substances (Minimum Degrees of Hazard) Regulations2001.January 2012 EPA0109
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