Chapter 2 - University of British Columbia
Chapter 2 - University of British Columbia
Chapter 2 - University of British Columbia
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51. Tonon G, Wong KK, Maulik G, Brennan C, Feng B, Zhang Y, Khatry DB, Protopopov A,<br />
You MJ, Aguirre AJ et al: High-resolution genomic pr<strong>of</strong>iles <strong>of</strong> human lung cancer.<br />
Proc Natl Acad Sci U S A 2005, 102(27):9625-9630.<br />
52. Lockwood WW, Chari R, Coe BP, Girard L, Macaulay C, Lam S, Gazdar AF, Minna JD,<br />
Lam WL: DNA amplification is a ubiquitous mechanism <strong>of</strong> oncogene activation in<br />
lung and other cancers. Oncogene 2008, 27(33):4615-4624.<br />
53. Cavenee WK: Loss <strong>of</strong> heterozygosity in stages <strong>of</strong> malignancy. Clin Chem 1989,<br />
35(7 Suppl):B48-52.<br />
54. Bepler G, Garcia-Blanco MA: Three tumor-suppressor regions on chromosome 11p<br />
identified by high-resolution deletion mapping in human non-small-cell lung<br />
cancer. Proc Natl Acad Sci U S A 1994, 91(12):5513-5517.<br />
55. Fong KM, Zimmerman PV, Smith PJ: Microsatellite instability and other molecular<br />
abnormalities in non-small cell lung cancer. Cancer Res 1995, 55(1):28-30.<br />
56. Merlo A, Gabrielson E, Askin F, Sidransky D: Frequent loss <strong>of</strong> chromosome 9 in<br />
human primary non-small cell lung cancer. Cancer Res 1994, 54(3):640-642.<br />
57. Merlo A, Gabrielson E, Mabry M, Vollmer R, Baylin SB, Sidransky D: Homozygous<br />
deletion on chromosome 9p and loss <strong>of</strong> heterozygosity on 9q, 6p, and 6q in<br />
primary human small cell lung cancer. Cancer Res 1994, 54(9):2322-2326.<br />
58. Sundaresan V, Heppell-Parton A, Coleman N, Miozzo M, Sozzi G, Ball R, Cary N,<br />
Hasleton P, Fowler W, Rabbitts P: Somatic genetic changes in lung cancer and<br />
precancerous lesions. Ann Oncol 1995, 6 Suppl 1:27-31; discussion 31-22.<br />
59. Huang J, Wei W, Chen J, Zhang J, Liu G, Di X, Mei R, Ishikawa S, Aburatani H, Jones<br />
KW et al: CARAT: a novel method for allelic detection <strong>of</strong> DNA copy number<br />
changes using high density oligonucleotide arrays. BMC Bioinformatics 2006, 7:83.<br />
60. Yamamoto G, Nannya Y, Kato M, Sanada M, Levine RL, Kawamata N, Hangaishi A,<br />
Kurokawa M, Chiba S, Gilliland DG et al: Highly sensitive method for genomewide<br />
detection <strong>of</strong> allelic composition in nonpaired, primary tumor specimens by use <strong>of</strong><br />
affymetrix single-nucleotide-polymorphism genotyping microarrays. Am J Hum<br />
Genet 2007, 81(1):114-126.<br />
61. LaFramboise T, Weir BA, Zhao X, Beroukhim R, Li C, Harrington D, Sellers WR,<br />
Meyerson M: Allele-specific amplification in cancer revealed by SNP array<br />
analysis. PLoS Comput Biol 2005, 1(6):e65.<br />
62. Li C, Beroukhim R, Weir BA, Winckler W, Garraway LA, Sellers WR, Meyerson M: Major<br />
copy proportion analysis <strong>of</strong> tumor samples using SNP arrays. BMC Bioinformatics<br />
2008, 9:204.<br />
63. Lin M, Wei LJ, Sellers WR, Lieberfarb M, Wong WH, Li C: dChipSNP: significance<br />
curve and clustering <strong>of</strong> SNP-array-based loss-<strong>of</strong>-heterozygosity data.<br />
Bioinformatics 2004, 20(8):1233-1240.<br />
64. Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C,<br />
Greulich H, Muzny DM, Morgan MB et al: Somatic mutations affect key pathways in<br />
lung adenocarcinoma. Nature 2008, 455(7216):1069-1075.<br />
65. Suda K, Tomizawa K, Mitsudomi T: Biological and clinical significance <strong>of</strong> KRAS<br />
mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation.<br />
Cancer Metastasis Rev 2010.<br />
66. Feinberg AP: Phenotypic plasticity and the epigenetics <strong>of</strong> human disease. Nature<br />
2007, 447(7143):433-440.<br />
67. Feinberg AP, Gehrke CW, Kuo KC, Ehrlich M: Reduced genomic 5-methylcytosine<br />
content in human colonic neoplasia. Cancer Res 1988, 48(5):1159-1161.<br />
68. Feinberg AP, Tycko B: The history <strong>of</strong> cancer epigenetics. Nat Rev Cancer 2004,<br />
4(2):143-153.<br />
69. Lo PK, Sukumar S: Epigenomics and breast cancer. Pharmacogenomics 2008,<br />
9(12):1879-1902.<br />
70. Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716. Drugs<br />
R D 2003, 4(3):179-184.<br />
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