ACE C18-AR and C18-PFP - Hplc.eu

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®ACEHPLC / UHPLC ColumnsSummary: Unwanted Selectivity Changes44Pressure induced k and changes may be seen forany manufacturer phases under UHPLC conditionsChanges in selectivity and retention may be significantwith ionised analytes and large MW analytes a , but theimpact on neutral molecules is typically smallerCurrent discussions / theory focus on changes inanalyte molar volume as the principle cause forchanges in k and observedSuccessful HPLC ↔ UHPLC possible...the analyst justneeds to be vigilanta Fallas et al. / J. Chromatogr. A 1209 (2008) 195–205
®ACEHPLC / UHPLC Columns45Connections : Losses in N and A sPeak Dispersion
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ACE C18-AR and C18-PFP - Hplc.eu

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