ACE C18-AR and C18-PFP - Hplc.eu
ACE C18-AR and C18-PFP - Hplc.eu
ACE C18-AR and C18-PFP - Hplc.eu
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®<strong>ACE</strong>HPLC / UHPLC Columns<strong>ACE</strong> ® <strong>C18</strong>-<strong>PFP</strong>: Multi-Mode Separation Mechanism20Combining the character of <strong>C18</strong>+<strong>PFP</strong> into a single individualphase harnesses the best of both phases for unique selectivitySeparationmechanismTypical<strong>C18</strong>Typical<strong>PFP</strong><strong>ACE</strong> ®<strong>C18</strong>-<strong>PFP</strong>Hydrophobicity ++++ + / ++ ++++- Interaction - +++ +++Dipole - Dipole - ++++ ++++Hydrogen Bonding - +++ +++Shape Selectivity ++ +++ ++++The predominance of each retention mechanism will bedictated by the analyte’s physicochemical properties, itsstructure <strong>and</strong> the chromatographic conditions appliedMulti-Mode Interactions Offer the Chromatographer More