ACE C18-AR and C18-PFP - Hplc.eu
ACE C18-AR and C18-PFP - Hplc.eu
ACE C18-AR and C18-PFP - Hplc.eu
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®<strong>ACE</strong>HPLC / UHPLC ColumnsAromatic Functionality – Engineering New Stationary Phases14Phases with aromatic functionality include phenyl <strong>and</strong>pentafluorophenyl (<strong>PFP</strong>) based lig<strong>and</strong>s−−AdvantagesAromatic functionality potentially offer unique interactions withanalytes (c.f. <strong>C18</strong>) giving alternative selectivityProvides enhanced retention of polar compounds− Many aromatic functionality-based phases can be used in 100%aqueous eluents−−DisadvantagesPhenyl / <strong>PFP</strong> phases may suffer phase bleedBatch-to-batch reproducibility & robustness may be weak
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